10 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EXO1	Rad2 family nuclease. (699 aa)
	DNA2	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease. (1426 aa)
	TUB1	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	RAD57	Putative DNA-dependent ATPase. (511 aa)
	RAD53	Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. (699 aa)
	AGO1	Ago1p; Belongs to the argonaute family. (917 aa)
	SNZ1	Pyridoxine biosynthesis protein; Belongs to the PdxS/SNZ family. (292 aa)
	RDH54	DNA-dependent ATPase. (796 aa)
	RAD51	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (361 aa)
	RAD52	Recombinase. (564 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNA2	EXO1	A0A1D8PPB3	A0A1D8PMZ2	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease.	Rad2 family nuclease.	0.984
DNA2	RAD51	A0A1D8PPB3	Q59UY8	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.867
DNA2	RAD52	A0A1D8PPB3	Q59NG2	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease.	Recombinase.	0.935
DNA2	RAD53	A0A1D8PPB3	A0A1D8PJZ1	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease.	Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.	0.659
DNA2	RAD57	A0A1D8PPB3	A0A1D8PI62	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease.	Putative DNA-dependent ATPase.	0.864
DNA2	RDH54	A0A1D8PPB3	Q5A5N2	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease.	DNA-dependent ATPase.	0.625
EXO1	DNA2	A0A1D8PMZ2	A0A1D8PPB3	Rad2 family nuclease.	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease.	0.984
EXO1	RAD51	A0A1D8PMZ2	Q59UY8	Rad2 family nuclease.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.991
EXO1	RAD52	A0A1D8PMZ2	Q59NG2	Rad2 family nuclease.	Recombinase.	0.946
EXO1	RAD53	A0A1D8PMZ2	A0A1D8PJZ1	Rad2 family nuclease.	Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.	0.751
EXO1	RAD57	A0A1D8PMZ2	A0A1D8PI62	Rad2 family nuclease.	Putative DNA-dependent ATPase.	0.906
EXO1	RDH54	A0A1D8PMZ2	Q5A5N2	Rad2 family nuclease.	DNA-dependent ATPase.	0.688
RAD51	DNA2	Q59UY8	A0A1D8PPB3	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease.	0.867
RAD51	EXO1	Q59UY8	A0A1D8PMZ2	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Rad2 family nuclease.	0.991
RAD51	RAD52	Q59UY8	Q59NG2	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Recombinase.	0.999
RAD51	RAD53	Q59UY8	A0A1D8PJZ1	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.	0.842
RAD51	RAD57	Q59UY8	A0A1D8PI62	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Putative DNA-dependent ATPase.	0.986
RAD51	RDH54	Q59UY8	Q5A5N2	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DNA-dependent ATPase.	0.972
RAD52	DNA2	Q59NG2	A0A1D8PPB3	Recombinase.	Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease.	0.935
RAD52	EXO1	Q59NG2	A0A1D8PMZ2	Recombinase.	Rad2 family nuclease.	0.946