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| | APQ09991.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa) |
| | APQ10004.1 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa) |
| | minC | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (248 aa) |
| | zipA | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (301 aa) |
| | rlmM | 23S rRNA (cytidine(2498)-2'-O)-methyltransferase RlmM; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (353 aa) |
| | nfuA | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (194 aa) |
| | APQ10431.1 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. (342 aa) |
| | uppP | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (278 aa) |
| | APQ10485.1 | 23S rRNA pseudouridylate synthase B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (349 aa) |
| | deaD | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (564 aa) |
| | APQ10589.1 | Serine-type D-Ala-D-Ala carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (385 aa) |
| | APQ10619.1 | Structural protein MipA; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa) |
| | APQ10702.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa) |
| | rlmE | 23S rRNA (uridine(2552)-2'-O)-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (206 aa) |
| | APQ10798.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa) |
| | APQ10823.1 | RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (437 aa) |
| | APQ10851.1 | C-type cytochrome biogenesis protein CcmI; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa) |
| | APQ10852.1 | Cytochrome c-type biogenesis protein CcmH; Possible subunit of a heme lyase. (150 aa) |
| | APQ10853.1 | Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa) |
| | APQ10854.1 | Cytochrome c-type biogenesis protein; required for the transfer of heme to apocytochrome c; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa) |
| | ccmE | Cytochrome c biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (151 aa) |
| | APQ10856.1 | Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (58 aa) |
| | ccmC | Heme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (248 aa) |
| | APQ10858.1 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (223 aa) |
| | ccmA | Heme ABC transporter ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (201 aa) |
| | APQ10860.1 | Flagellar hook-length control protein FliK; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa) |
| | rlmD | 23S rRNA (uracil(1939)-C(5))-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (453 aa) |
| | APQ10977.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa) |
| | cpoB | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (277 aa) |
| | flhA | Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (699 aa) |
| | flhB | Flagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (382 aa) |
| | APQ11133.1 | Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (258 aa) |
| | fliQ | Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa) |
| | APQ11139.1 | Flagellar hook-length control protein FliK; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa) |
| | fliI | Flagellum-specific ATP synthase FliI; Involved in type III protein export during flagellum assembly; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa) |
| | APQ14432.1 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa) |
| | APQ11183.1 | Flagellar export chaperone FliS; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa) |
| | APQ11195.1 | Flagellar hook-associated protein FlgK; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flagella basal body rod proteins family. (679 aa) |
| | APQ11196.1 | Flagellar rod assembly protein/muramidase FlgJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa) |
| | APQ11207.1 | Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (252 aa) |
| | APQ11209.1 | Flagellar protein FlgN; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa) |
| | APQ11218.1 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa) |
| | APQ11226.1 | Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa) |
| | APQ11312.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | APQ11342.1 | Pilus assembly protein PilZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (352 aa) |
| | APQ11353.1 | Metal-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa) |
| | APQ11357.1 | 23S rRNA pseudouridine(955/2504/2580) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (317 aa) |
| | rne | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1094 aa) |
| | APQ11369.1 | Fe-S metabolism protein SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa) |
| | APQ11453.1 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa) |
| | der | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (495 aa) |
| | bamB | Outer membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (380 aa) |
| | APQ11462.1 | Type IV pilus biogenesis/stability protein PilW; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa) |
| | rlmN | 23S rRNA (adenine(2503)-C(2))-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (379 aa) |
| | APQ11465.1 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa) |
| | hscA | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (619 aa) |
| | hscB | Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (173 aa) |
| | APQ11469.1 | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. (107 aa) |
| | APQ11470.1 | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa) |
| | iscS | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (404 aa) |
| | APQ11474.1 | Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the inositol monophosphatase superfamily. (271 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (340 aa) |
| | nagZ | beta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (325 aa) |
| | APQ11500.1 | Cell division protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (166 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (393 aa) |
| | ftsQ | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (283 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (486 aa) |
| | murG | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (356 aa) |
| | ftsW | Putative lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (400 aa) |
| | murD | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (447 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (455 aa) |
| | murE | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (489 aa) |
| | ftsI | Cell division protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (585 aa) |
| | rsmH | 16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (313 aa) |
| | rsmI | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (281 aa) |
| | APQ11620.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa) |
| | APQ11664.1 | Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa) |
| | rimM | Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (178 aa) |
| | APQ11708.1 | Inner membrane protein YpjD; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa) |
| | APQ11715.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa) |
| | APQ11731.1 | Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (290 aa) |
| | APQ11740.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa) |
| | APQ11741.1 | Pilus assembly protein PilW; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa) |
| | APQ11742.1 | Type IV pilus modification protein PilV; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa) |
| | APQ11743.1 | Type II secretion system protein GspH; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa) |
| | APQ11746.1 | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (319 aa) |
| | bamD | Outer membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (341 aa) |
| | APQ11753.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa) |
| | APQ11754.1 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa) |
| | APQ11755.1 | Type IV pilus modification protein PilV; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa) |
| | APQ11756.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa) |
| | APQ11757.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa) |
| | APQ14454.1 | Type IV pilin; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa) |
| | murJ | Murein biosynthesis integral membrane protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (512 aa) |
| | obgE | GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (403 aa) |
| | APQ11962.1 | Pilus assembly protein PilE; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa) |
| | APQ11964.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa) |
| | APQ11965.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa) |
| | APQ11966.1 | Type IV pilus modification protein PilV; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa) |
| | APQ11967.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa) |
| | APQ12008.1 | D-alanyl-D-alanine endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (303 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (337 aa) |
| | rlmB | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (249 aa) |
| | rsgA | Ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (340 aa) |
| | mpl | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (451 aa) |
| | uppP-2 | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (290 aa) |
| | APQ12239.1 | Virulence factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa) |
| | APQ12270.1 | GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (605 aa) |
| | secB | Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (154 aa) |
| | APQ12285.1 | Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. (448 aa) |
| | APQ12347.1 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa) |
| | ftsI-2 | Cell division protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (567 aa) |
| | APQ12480.1 | Curli production assembly protein CsgE; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa) |
| | APQ12481.1 | Curli production assembly protein CsgF; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa) |
| | APQ12482.1 | Curli production assembly/transport protein CsgG; Involved in the stability of the curlin proteins during assembly; involved in the secretion of the major curlin subunit CsgA across the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa) |
| | APQ12592.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (433 aa) |
| | rsmG | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (214 aa) |
| | glmU | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (455 aa) |
| | engB | YihA family ribosome biogenesis GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (212 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (240 aa) |
| | APQ12833.1 | YicC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa) |
| | cyaY | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (109 aa) |
| | APQ12910.1 | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (102 aa) |
| | rsmA | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (263 aa) |
| | surA | Peptidylprolyl isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (431 aa) |
| | lptD | LPS biosynthesis protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (911 aa) |
| | APQ12967.1 | Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa) |
| | APQ12968.1 | Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa) |
| | APQ13010.1 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (780 aa) |
| | bamE | Hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (178 aa) |
| | APQ13033.1 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa) |
| | rimP | Ribosome maturation factor RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (152 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (127 aa) |
| | ureE | Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (166 aa) |
| | erpA | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. (116 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (263 aa) |
| | dsbD | Protein-disulfide reductase DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (587 aa) |
| | APQ13175.1 | Translation initiation factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa) |
| | APQ13184.1 | 16S rRNA (uracil(1498)-N(3))-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (236 aa) |
| | APQ13204.1 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (808 aa) |
| | APQ13205.1 | Pilus assembly protein PilM; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa) |
| | APQ13206.1 | Pilus assembly protein PilN; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa) |
| | APQ13207.1 | Pilus assembly protein PilP; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa) |
| | APQ14532.1 | Pilus assembly protein PilP; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa) |
| | APQ14533.1 | Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (740 aa) |
| | APQ13224.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (189 aa) |
| | mtgA | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (233 aa) |
| | APQ13255.1 | Holliday junction DNA helicase RuvA; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (150 aa) |
| | APQ13268.1 | 16S rRNA (uracil(1498)-N(3))-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (242 aa) |
| | rsmC | 16S rRNA methyltransferase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. (333 aa) |
| | rlmG | 50S rRNA methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (376 aa) |
| | APQ13374.1 | ATP-dependent helicase HrpB; Derived by automated computational analysis using gene prediction method: Protein Homology. (834 aa) |
| | APQ13434.1 | Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (204 aa) |
| | rlmJ | 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ; Specifically methylates the adenine in position 2030 of 23S rRNA. (278 aa) |
| | rsmJ | rRNA methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA. (259 aa) |
| | APQ13502.1 | Folate-binding protein YgfZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (229 aa) |
| | era | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (301 aa) |
| | APQ13569.1 | GTPase SAR1; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa) |
| | rlmF | 23S rRNA (adenine(1618)-N(6))-methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA. (308 aa) |
| | APQ13595.1 | 16S rRNA pseudouridine(516) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (234 aa) |
| | rsfS | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (116 aa) |
| | rlmH | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (155 aa) |
| | mrdA | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (635 aa) |
| | mrdB | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (383 aa) |
| | APQ13656.1 | Serine-type D-Ala-D-Ala carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (386 aa) |
| | lptE | Hypothetical protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (204 aa) |
| | APQ13673.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa) |
| | ybeY | rRNA maturation RNase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (151 aa) |
| | APQ13790.1 | Ribonuclease E/G; Involved in the processing of the 5'end of 16S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa) |
| | lptA | Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (180 aa) |
| | lptC | LPS export ABC transporter periplasmic protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. (189 aa) |
| | APQ13811.1 | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (79 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa) |
| | uppS | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (247 aa) |
| | bamA | Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (789 aa) |
| | rlmL | 23S rRNA (guanine(2445)-N(2))/(guanine(2069)-N(7))- methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (723 aa) |
| | APQ13978.1 | Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa) |
| | APQ13995.1 | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (122 aa) |
| | APQ14020.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa) |
| | rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | APQ14122.1 | D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa) |
| | APQ14269.1 | Fe-S-binding ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa) |
| | APQ14273.1 | LD-carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa) |
| | APQ14279.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa) |
| | APQ14333.1 | ATP-dependent RNA helicase HrpA; Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; Derived by automated computational analysis using gene prediction method: Protein Homology. (1341 aa) |
| | APQ14354.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa) |
