STRINGSTRING
UMAG_06087 UMAG_06087 UMAG_12318 UMAG_12318 UMAG_05381 UMAG_05381 UMAG_05490 UMAG_05490 UMAG_04704 UMAG_04704 UMAG_04914 UMAG_04914 UMAG_04989 UMAG_04989 UMAG_10910 UMAG_10910 UMAG_03676 UMAG_03676 UMAG_03792 UMAG_03792 UMAG_03481 UMAG_03481 UMAG_02823 UMAG_02823 UMAG_02935 UMAG_02935 UMAG_02543 UMAG_02543 UMAG_11929 UMAG_11929 UMAG_05228 UMAG_05228 UMAG_00920 UMAG_00920 UMAG_01110 UMAG_01110 UMAG_10237 UMAG_10237 UMAG_12076 UMAG_12076 UMAG_12336 UMAG_12336 UMAG_00290 UMAG_00290 UMAG_10101 UMAG_10101 UMAG_11163 UMAG_11163 UMAG_04976 UMAG_04976 UMAG_05064 UMAG_05064 UMAG_15011 UMAG_15011 UMAG_03886 UMAG_03886 UMAG_03434 UMAG_03434 UMAG_03141 UMAG_03141 UMAG_10656 UMAG_10656 UMAG_11009 UMAG_11009 UMAG_06506 UMAG_06506 UMAG_05156 UMAG_05156 UMAG_11783 UMAG_11783 UMAG_01458 UMAG_01458 UMAG_01679 UMAG_01679 UMAG_00911 UMAG_00911 UMAG_00625 UMAG_00625 UMAG_00657 UMAG_00657 UMAG_06213 UMAG_06213 MCM7 MCM7 UMAG_06219 UMAG_06219 UMAG_05846 UMAG_05846 UMAG_12032 UMAG_12032 UMAG_04927 UMAG_04927 UMAG_04785 UMAG_04785 UMAG_06358 UMAG_06358 UMAG_04623 UMAG_04623 UMAG_05028 UMAG_05028 UMAG_03898 UMAG_03898 UMAG_04529 UMAG_04529 UMAG_04630 UMAG_04630 UMAG_05403 UMAG_05403 UMAG_04165 UMAG_04165 UMAG_10669 UMAG_10669 UMAG_10396 UMAG_10396 UMAG_11010 UMAG_11010 UMAG_03756 UMAG_03756 UMAG_03766 UMAG_03766 UMAG_03852 UMAG_03852 UMAG_04344 UMAG_04344 UMAG_04390 UMAG_04390 UMAG_04442 UMAG_04442 UMAG_03288 UMAG_03288 UMAG_02557 UMAG_02557 UMAG_11475 UMAG_11475 UMAG_02863 UMAG_02863 UMAG_02760 UMAG_02760 UMAG_03001 UMAG_03001 UMAG_03025 UMAG_03025 UMAG_10286 UMAG_10286 UMAG_11724 UMAG_11724 UMAG_03394 UMAG_03394 UMAG_10135 UMAG_10135 UMAG_02083 UMAG_02083 UMAG_03496 UMAG_03496 UMAG_02342 UMAG_02342 UMAG_05118 UMAG_05118 UMAG_03200 UMAG_03200 UMAG_01445 UMAG_01445 UMAG_10830 UMAG_10830 UMAG_05085 UMAG_05085 UMAG_05141 UMAG_05141 UMAG_01605 UMAG_01605 UMAG_05208 UMAG_05208 UMAG_10318 UMAG_10318 UMAG_03095 UMAG_03095 UMAG_11687 UMAG_11687 UMAG_01931 UMAG_01931 UMAG_01646 UMAG_01646 UMAG_02579 UMAG_02579 UMAG_00869 UMAG_00869 UMAG_02220 UMAG_02220 UMAG_01293 UMAG_01293 UMAG_01085 UMAG_01085 UMAG_01191 UMAG_01191 UMAG_00216 UMAG_00216 UMAG_00366 UMAG_00366 UMAG_00389 UMAG_00389 UMAG_01691 UMAG_01691 UMAG_01742 UMAG_01742 UMAG_01932 UMAG_01932 UMAG_10100 UMAG_10100 UMAG_11652 UMAG_11652 UMAG_00729 UMAG_00729 UMAG_00101 UMAG_00101 UMAG_12155 UMAG_12155 UMAG_00527 UMAG_00527 UMAG_00728 UMAG_00728 CHK1 CHK1 REC1 REC1 FEN1 FEN1 MSH3 MSH3 TOF1 TOF1 SLX1 SLX1 POL2 POL2 RAD5 RAD5 TSD2 TSD2 RAD51 RAD51
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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UMAG_06087Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (980 aa)
UMAG_12318Uncharacterized protein. (231 aa)
UMAG_05381Chromosome 19, whole genome shotgun sequence. (1346 aa)
UMAG_05490Uncharacterized protein. (813 aa)
UMAG_04704Mre11_DNA_bind domain-containing protein. (883 aa)
UMAG_04914Chromosome 15, whole genome shotgun sequence. (445 aa)
UMAG_04989Chromosome 15, whole genome shotgun sequence. (722 aa)
UMAG_10910Uncharacterized protein. (381 aa)
UMAG_03676Chromosome 10, whole genome shotgun sequence. (1060 aa)
UMAG_03792Chromosome 10, whole genome shotgun sequence. (1191 aa)
UMAG_03481Chromosome 9, whole genome shotgun sequence. (828 aa)
UMAG_02823Chromosome 7, whole genome shotgun sequence. (1104 aa)
UMAG_02935Chromosome 7, whole genome shotgun sequence. (268 aa)
UMAG_02543Uncharacterized protein. (869 aa)
UMAG_11929DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (986 aa)
UMAG_05228Uncharacterized protein. (447 aa)
UMAG_00920Putative DNA replication factor C subunit protein. (353 aa)
UMAG_01110Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2637 aa)
UMAG_10237Protein kinase domain-containing protein. (618 aa)
UMAG_12076Unplaced genomic scaffold um_scaf_contig_1.265, whole genome shotgun sequence. (376 aa)
UMAG_12336Chromosome 23, whole genome shotgun sequence. (1070 aa)
UMAG_00290Chromosome 1, whole genome shotgun sequence. (1206 aa)
UMAG_10101Chromosome 1, whole genome shotgun sequence. (610 aa)
UMAG_11163Chromosome 15, whole genome shotgun sequence. (921 aa)
UMAG_04976Chromosome 15, whole genome shotgun sequence. (510 aa)
UMAG_05064DNA helicase; Belongs to the MCM family. (731 aa)
UMAG_15011Chromosome 12, whole genome shotgun sequence; Belongs to the PI3/PI4-kinase family. (3138 aa)
UMAG_03886Uncharacterized protein. (919 aa)
UMAG_03434Replication factor C subunit 1. (950 aa)
UMAG_03141Chromosome 8, whole genome shotgun sequence. (828 aa)
UMAG_10656DNA primase; Belongs to the eukaryotic-type primase small subunit family. (492 aa)
UMAG_11009DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1315 aa)
UMAG_06506Chromosome 7, whole genome shotgun sequence. (983 aa)
UMAG_05156Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (623 aa)
UMAG_11783DUF1767 domain-containing protein. (451 aa)
UMAG_01458DNA polymerase. (1057 aa)
UMAG_01679DNA helicase. (906 aa)
UMAG_00911Uncharacterized protein. (1490 aa)
UMAG_00625Chromosome 1, whole genome shotgun sequence. (997 aa)
UMAG_00657Chromosome 1, whole genome shotgun sequence. (650 aa)
UMAG_06213Uncharacterized protein. (1143 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (846 aa)
UMAG_06219Uncharacterized protein. (334 aa)
UMAG_05846DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1127 aa)
UMAG_12032Uncharacterized protein. (560 aa)
UMAG_04927Chromosome 15, whole genome shotgun sequence. (219 aa)
UMAG_04785Checkpoint protein; Belongs to the HUS1 family. (285 aa)
UMAG_06358Chromosome 23, whole genome shotgun sequence. (867 aa)
UMAG_04623Putative replication factor C subunit 3. (341 aa)
UMAG_05028Chromosome 15, whole genome shotgun sequence. (1454 aa)
UMAG_03898Uncharacterized protein. (1532 aa)
UMAG_04529DNA polymerase. (1667 aa)
UMAG_04630ERCC4 domain-containing protein. (605 aa)
UMAG_05403Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (289 aa)
UMAG_04165Chromosome 12, whole genome shotgun sequence. (114 aa)
UMAG_10669Chromosome 10, whole genome shotgun sequence. (892 aa)
UMAG_10396Chromosome 8, whole genome shotgun sequence. (993 aa)
UMAG_11010Chromosome 8, whole genome shotgun sequence. (395 aa)
UMAG_03756Chromosome 10, whole genome shotgun sequence. (1166 aa)
UMAG_03766Chromosome 10, whole genome shotgun sequence. (559 aa)
UMAG_03852DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (543 aa)
UMAG_04344XPGN domain-containing protein. (699 aa)
UMAG_04390RRM domain-containing protein. (390 aa)
UMAG_04442Putative asparagine--tRNA ligase DED81. (583 aa)
UMAG_03288Chromosome 8, whole genome shotgun sequence. (249 aa)
UMAG_02557DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (764 aa)
UMAG_11475Chromosome 7, whole genome shotgun sequence. (393 aa)
UMAG_02863Chromosome 7, whole genome shotgun sequence. (864 aa)
UMAG_02760DNA_pol_E_B domain-containing protein. (632 aa)
UMAG_03001Chromosome 7, whole genome shotgun sequence. (887 aa)
UMAG_03025Chromosome 7, whole genome shotgun sequence; Component of the post-replicative DNA mismatch repair system (MMR). (963 aa)
UMAG_10286Putative nuclear transport factor. (120 aa)
UMAG_11724XPA_C domain-containing protein. (356 aa)
UMAG_03394Chromosome 9, whole genome shotgun sequence. (958 aa)
UMAG_10135Zf-primase domain-containing protein. (1006 aa)
UMAG_02083Putative DNA-dependent ATPase. (870 aa)
UMAG_03496Chromosome 9, whole genome shotgun sequence. (793 aa)
UMAG_02342Uncharacterized protein. (857 aa)
UMAG_05118zf-4CXXC_R1 domain-containing protein. (1020 aa)
UMAG_03200Chromosome 8, whole genome shotgun sequence. (1075 aa)
UMAG_01445DNA helicase; Belongs to the MCM family. (961 aa)
UMAG_10830Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (955 aa)
UMAG_05085Uncharacterized protein. (500 aa)
UMAG_05141UmuC domain-containing protein. (682 aa)
UMAG_01605Uncharacterized protein. (789 aa)
UMAG_05208DNA_mis_repair domain-containing protein. (831 aa)
UMAG_10318Chromosome 7, whole genome shotgun sequence. (351 aa)
UMAG_03095Chromosome 7, whole genome shotgun sequence. (781 aa)
UMAG_11687Uncharacterized protein. (517 aa)
UMAG_01931DNA polymerase. (1678 aa)
UMAG_01646DNA helicase; Belongs to the MCM family. (1020 aa)
UMAG_02579Uncharacterized protein. (285 aa)
UMAG_008693'-5' exonuclease domain-containing protein. (646 aa)
UMAG_02220Uncharacterized protein. (1488 aa)
UMAG_01293UmuC domain-containing protein. (763 aa)
UMAG_01085Putative DNA repair protein. (1309 aa)
UMAG_01191Uncharacterized protein. (630 aa)
UMAG_00216Chromosome 1, whole genome shotgun sequence. (384 aa)
UMAG_00366DNA helicase; Belongs to the MCM family. (980 aa)
UMAG_00389Chromosome 1, whole genome shotgun sequence. (769 aa)
UMAG_01691Uncharacterized protein. (1176 aa)
UMAG_01742HORMA domain-containing protein. (434 aa)
UMAG_01932Uncharacterized protein. (971 aa)
UMAG_10100Chromosome 1, whole genome shotgun sequence. (215 aa)
UMAG_11652Sld5 domain-containing protein. (303 aa)
UMAG_00729Chromosome 1, whole genome shotgun sequence. (343 aa)
UMAG_00101Chromosome 1, whole genome shotgun sequence. (865 aa)
UMAG_12155Chromosome 1, whole genome shotgun sequence. (915 aa)
UMAG_00527Chromosome 1, whole genome shotgun sequence. (170 aa)
UMAG_00728Chromosome 1, whole genome shotgun sequence. (706 aa)
CHK1Serine/threonine-protein kinase CHK1; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles (By similarity). (662 aa)
REC1DNA repair exonuclease REC1; Plays a central role in regulating the genetic system of this fungus. Has a 3'-->5' exonuclease activity. Belongs to the rad1 family. (463 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (374 aa)
MSH3DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] (1154 aa)
TOF1Topoisomerase 1-associated factor 1; Involved in chromosome segregation during meiosis and DNA damage repair; Belongs to the timeless family. (1251 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (658 aa)
POL2DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication. (2305 aa)
RAD5DNA repair protein RAD5; Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity). (1387 aa)
TSD2Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. (845 aa)
RAD51DNA repair protein RAD51; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (339 aa)
Your Current Organism:
Ustilago maydis
NCBI taxonomy Id: 237631
Other names: U. maydis 521, Ustilago maydis 521
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