STRINGSTRING
UMAG_00728 UMAG_00728 UMAG_00101 UMAG_00101 UMAG_11652 UMAG_11652 UMAG_10100 UMAG_10100 UMAG_00754 UMAG_00754 UMAG_00592 UMAG_00592 UMAG_00172 UMAG_00172 UMAG_00399 UMAG_00399 UMAG_00366 UMAG_00366 UMAG_01191 UMAG_01191 UMAG_01085 UMAG_01085 UMAG_00878 UMAG_00878 UMAG_02579 UMAG_02579 UMAG_01646 UMAG_01646 UMAG_06299 UMAG_06299 UMAG_11881 UMAG_11881 UMAG_01445 UMAG_01445 UMAG_05118 UMAG_05118 UMAG_02065 UMAG_02065 UMAG_10135 UMAG_10135 UMAG_03025 UMAG_03025 UMAG_03001 UMAG_03001 UMAG_02760 UMAG_02760 PIF1 PIF1 UMAG_02557 UMAG_02557 UMAG_03288 UMAG_03288 UMAG_04390 UMAG_04390 UMAG_03852 UMAG_03852 UMAG_03766 UMAG_03766 UMAG_03806 UMAG_03806 UMAG_03740 UMAG_03740 UMAG_05403 UMAG_05403 UMAG_04529 UMAG_04529 UMAG_11545 UMAG_11545 UMAG_06410 UMAG_06410 UMAG_06358 UMAG_06358 UMAG_04389 UMAG_04389 UMAG_04381 UMAG_04381 UMAG_04785 UMAG_04785 UMAG_04927 UMAG_04927 MCM7 MCM7 UMAG_06037 UMAG_06037 UMAG_00625 UMAG_00625 UMAG_11302 UMAG_11302 UMAG_01679 UMAG_01679 UMAG_01458 UMAG_01458 UMAG_05156 UMAG_05156 UMAG_02404 UMAG_02404 UMAG_10071 UMAG_10071 UMAG_02775 UMAG_02775 UMAG_02591 UMAG_02591 UMAG_10656 UMAG_10656 UMAG_03244 UMAG_03244 UMAG_03743 UMAG_03743 UMAG_15082 UMAG_15082 UMAG_10420 UMAG_10420 UMAG_05064 UMAG_05064 UMAG_04976 UMAG_04976 UMAG_00575 UMAG_00575 UMAG_00439 UMAG_00439 UMAG_10101 UMAG_10101 UMAG_12336 UMAG_12336 UMAG_11308 UMAG_11308 UMAG_01122 UMAG_01122 UMAG_02543 UMAG_02543 UMAG_03792 UMAG_03792 UMAG_04013 UMAG_04013 UMAG_04230 UMAG_04230 UMAG_04603 UMAG_04603 UMAG_10910 UMAG_10910 UMAG_10347 UMAG_10347 UMAG_05381 UMAG_05381 UMAG_05863 UMAG_05863 RAD51 RAD51 HTZ1 HTZ1 INO80 INO80 SWC4 SWC4 POL2 POL2 YAF9 YAF9 HTA1 HTA1 SLX1 SLX1 TOF1 TOF1 EAF3 EAF3 RVB2 RVB2 SWC5 SWC5 POB3 POB3 HAT2 HAT2 SWR1 SWR1 RVB1 RVB1 REC1 REC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UMAG_00728Chromosome 1, whole genome shotgun sequence. (706 aa)
UMAG_00101Chromosome 1, whole genome shotgun sequence. (865 aa)
UMAG_11652Sld5 domain-containing protein. (303 aa)
UMAG_10100Chromosome 1, whole genome shotgun sequence. (215 aa)
UMAG_00754Chromosome 1, whole genome shotgun sequence. (166 aa)
UMAG_00592Chromosome 1, whole genome shotgun sequence. (869 aa)
UMAG_00172Chromosome 1, whole genome shotgun sequence. (647 aa)
UMAG_00399Chromosome 1, whole genome shotgun sequence. (943 aa)
UMAG_00366DNA helicase; Belongs to the MCM family. (980 aa)
UMAG_01191Uncharacterized protein. (630 aa)
UMAG_01085Putative DNA repair protein. (1309 aa)
UMAG_00878Bromo domain-containing protein. (826 aa)
UMAG_02579Uncharacterized protein. (285 aa)
UMAG_01646DNA helicase; Belongs to the MCM family. (1020 aa)
UMAG_06299MRC1 domain-containing protein. (2004 aa)
UMAG_11881PHD-type domain-containing protein. (1182 aa)
UMAG_01445DNA helicase; Belongs to the MCM family. (961 aa)
UMAG_05118zf-4CXXC_R1 domain-containing protein. (1020 aa)
UMAG_02065Histone deacetylase. (569 aa)
UMAG_10135Zf-primase domain-containing protein. (1006 aa)
UMAG_03025Chromosome 7, whole genome shotgun sequence; Component of the post-replicative DNA mismatch repair system (MMR). (963 aa)
UMAG_03001Chromosome 7, whole genome shotgun sequence. (887 aa)
UMAG_02760DNA_pol_E_B domain-containing protein. (632 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (706 aa)
UMAG_02557DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (764 aa)
UMAG_03288Chromosome 8, whole genome shotgun sequence. (249 aa)
UMAG_04390RRM domain-containing protein. (390 aa)
UMAG_03852DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (543 aa)
UMAG_03766Chromosome 10, whole genome shotgun sequence. (559 aa)
UMAG_03806Chromosome 10, whole genome shotgun sequence. (336 aa)
UMAG_03740Chromosome 10, whole genome shotgun sequence. (1250 aa)
UMAG_05403Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (289 aa)
UMAG_04529DNA polymerase. (1667 aa)
UMAG_11545YL1_C domain-containing protein. (199 aa)
UMAG_06410Chromosome 23, whole genome shotgun sequence. (796 aa)
UMAG_06358Chromosome 23, whole genome shotgun sequence. (867 aa)
UMAG_04389Structural maintenance of chromosomes protein. (1218 aa)
UMAG_04381Uncharacterized protein. (2080 aa)
UMAG_04785Checkpoint protein; Belongs to the HUS1 family. (285 aa)
UMAG_04927Chromosome 15, whole genome shotgun sequence. (219 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (846 aa)
UMAG_06037Chromosome 21, whole genome shotgun sequence. (653 aa)
UMAG_00625Chromosome 1, whole genome shotgun sequence. (997 aa)
UMAG_11302Chromatin modification-related protein. (538 aa)
UMAG_01679DNA helicase. (906 aa)
UMAG_01458DNA polymerase. (1057 aa)
UMAG_05156Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (623 aa)
UMAG_02404WD_REPEATS_REGION domain-containing protein. (951 aa)
UMAG_10071Uncharacterized protein. (216 aa)
UMAG_02775NDT80 domain-containing protein. (919 aa)
UMAG_02591Uncharacterized protein. (730 aa)
UMAG_10656DNA primase; Belongs to the eukaryotic-type primase small subunit family. (492 aa)
UMAG_03244Chromatin modification-related protein. (732 aa)
UMAG_03743Chromosome 10, whole genome shotgun sequence; Belongs to the actin family. (732 aa)
UMAG_15082Chromosome 10, whole genome shotgun sequence. (1851 aa)
UMAG_10420Chromosome 12, whole genome shotgun sequence. (393 aa)
UMAG_05064DNA helicase; Belongs to the MCM family. (731 aa)
UMAG_04976Chromosome 15, whole genome shotgun sequence. (510 aa)
UMAG_00575Chromosome 1, whole genome shotgun sequence. (882 aa)
UMAG_00439Chromosome 1, whole genome shotgun sequence. (323 aa)
UMAG_10101Chromosome 1, whole genome shotgun sequence. (610 aa)
UMAG_12336Chromosome 23, whole genome shotgun sequence. (1070 aa)
UMAG_11308Histone deacetylase. (585 aa)
UMAG_01122AAA domain-containing protein. (847 aa)
UMAG_02543Uncharacterized protein. (869 aa)
UMAG_03792Chromosome 10, whole genome shotgun sequence. (1191 aa)
UMAG_04013PAPA-1 domain-containing protein. (545 aa)
UMAG_04230Chromosome 12, whole genome shotgun sequence. (2115 aa)
UMAG_04603Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (918 aa)
UMAG_10910Uncharacterized protein. (381 aa)
UMAG_10347Uncharacterized protein; Belongs to the actin family. (813 aa)
UMAG_05381Chromosome 19, whole genome shotgun sequence. (1346 aa)
UMAG_05863Ubiquitin-like domain-containing protein. (93 aa)
RAD51DNA repair protein RAD51; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (339 aa)
HTZ1Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] (135 aa)
INO80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1910 aa)
SWC4SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (615 aa)
POL2DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication. (2305 aa)
YAF9Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). (431 aa)
HTA1Histone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (658 aa)
TOF1Topoisomerase 1-associated factor 1; Involved in chromosome segregation during meiosis and DNA damage repair; Belongs to the timeless family. (1251 aa)
EAF3Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (330 aa)
RVB2RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (476 aa)
SWC5SWR1-complex protein 5; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (354 aa)
POB3FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (558 aa)
HAT2Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. (433 aa)
SWR1Helicase SWR1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1830 aa)
RVB1RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (488 aa)
REC1DNA repair exonuclease REC1; Plays a central role in regulating the genetic system of this fungus. Has a 3'-->5' exonuclease activity. Belongs to the rad1 family. (463 aa)
Your Current Organism:
Ustilago maydis
NCBI taxonomy Id: 237631
Other names: U. maydis 521, Ustilago maydis 521
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