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FPR4 FPR4 UMAG_06412 UMAG_06412 UMAG_06167 UMAG_06167 UMAG_11230 UMAG_11230 UMAG_10220 UMAG_10220 UMAG_05053 UMAG_05053 UMAG_04026 UMAG_04026 UMAG_11929 UMAG_11929 UMAG_01720 UMAG_01720 UMAG_01772 UMAG_01772 UMAG_01802 UMAG_01802 UMAG_01018 UMAG_01018 UMAG_12081 UMAG_12081 UMAG_10038 UMAG_10038 UMAG_11231 UMAG_11231 UMAG_11600 UMAG_11600 UMAG_05339 UMAG_05339 UMAG_05549 UMAG_05549 UMAG_04797 UMAG_04797 UMAG_05627 UMAG_05627 UMAG_04310 UMAG_04310 UMAG_10536 UMAG_10536 UMAG_10990 UMAG_10990 UMAG_10420 UMAG_10420 UMAG_02884 UMAG_02884 UMAG_02923 UMAG_02923 UMAG_03057 UMAG_03057 UMAG_02177 UMAG_02177 UMAG_02305 UMAG_02305 UMAG_02376 UMAG_02376 UMAG_01599 UMAG_01599 UMAG_10870 UMAG_10870 UMAG_01763 UMAG_01763 UMAG_02022 UMAG_02022 UMAG_01014 UMAG_01014 UMAG_06003 UMAG_06003 UMAG_06058 UMAG_06058 UMAG_05352 UMAG_05352 UMAG_15066 UMAG_15066 UMAG_04703 UMAG_04703 UMAG_04739 UMAG_04739 UMAG_05002 UMAG_05002 UMAG_04838 UMAG_04838 UMAG_04983 UMAG_04983 UMAG_11022 UMAG_11022 UMAG_15008 UMAG_15008 UMAG_11054 UMAG_11054 UMAG_05416 UMAG_05416 UMAG_03726 UMAG_03726 CMU1 CMU1 UMAG_03501 UMAG_03501 UMAG_10982 UMAG_10982 UMAG_03103 UMAG_03103 UMAG_03299 UMAG_03299 UMAG_04220 UMAG_04220 UMAG_04066 UMAG_04066 UMAG_10079 UMAG_10079 UMAG_02797 UMAG_02797 UMAG_10156 UMAG_10156 UMAG_11778 UMAG_11778 UMAG_02974 UMAG_02974 UMAG_11882 UMAG_11882 UMAG_10627 UMAG_10627 UMAG_01935 UMAG_01935 UMAG_10248 UMAG_10248 UMAG_02097 UMAG_02097 UMAG_02115 UMAG_02115 UMAG_02308 UMAG_02308 UMAG_01718 UMAG_01718 UMAG_01853 UMAG_01853 UMAG_10271 UMAG_10271 UMAG_10273 UMAG_10273 UMAG_00685 UMAG_00685 UMAG_00043 UMAG_00043 UMAG_00486 UMAG_00486 CYP6 CYP6 ERG2 ERG2 TOP1 TOP1 UMAG_06287 UMAG_06287 CPR6 CPR6 RRD1 RRD1 CYP8 CYP8 RKI1 RKI1 CYP3 CYP3 CWC27 CWC27 UMAG_10306 UMAG_10306 CYP10 CYP10 RRD2 RRD2 fer4 fer4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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FPR4FK506-binding protein 4; PPIase that acts as a histone chaperone. Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail. Proline isomerization influences H3 methylation thereby regulating gene expression. (375 aa)
UMAG_06412Chromosome 23, whole genome shotgun sequence. (1037 aa)
UMAG_06167Mannose-6-phosphate isomerase. (468 aa)
UMAG_11230Uncharacterized protein. (737 aa)
UMAG_10220Chromosome 19, whole genome shotgun sequence. (970 aa)
UMAG_05053Chromosome 15, whole genome shotgun sequence. (217 aa)
UMAG_04026TRUD domain-containing protein. (811 aa)
UMAG_11929DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (986 aa)
UMAG_01720Putative phosphomannomutase. (619 aa)
UMAG_01772Uncharacterized protein. (462 aa)
UMAG_01802Uncharacterized protein; Belongs to the protein disulfide isomerase family. (398 aa)
UMAG_01018Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa)
UMAG_12081Chromosome 1, whole genome shotgun sequence. (283 aa)
UMAG_10038Chromosome 1, whole genome shotgun sequence. (911 aa)
UMAG_11231Putative glutathione S-transferase/histidinol dehydrogenase bifunctional related protein; Belongs to the GST superfamily. (516 aa)
UMAG_11600UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (375 aa)
UMAG_05339Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (206 aa)
UMAG_05549Putative myo-inositol 1-phosphate synthase (MIPS). (563 aa)
UMAG_04797Putative D-ribulose-5-phosphate 3-epimerase. (311 aa)
UMAG_05627Chromosome 16, whole genome shotgun sequence. (254 aa)
UMAG_04310Uncharacterized protein. (865 aa)
UMAG_10536Peptidylprolyl isomerase. (150 aa)
UMAG_10990PseudoU_synth_1 domain-containing protein. (660 aa)
UMAG_10420Chromosome 12, whole genome shotgun sequence. (393 aa)
UMAG_02884Chromosome 7, whole genome shotgun sequence. (357 aa)
UMAG_02923Chromosome 7, whole genome shotgun sequence. (282 aa)
UMAG_03057Chromosome 7, whole genome shotgun sequence. (446 aa)
UMAG_02177Uncharacterized protein. (1145 aa)
UMAG_02305TPR_REGION domain-containing protein. (191 aa)
UMAG_02376Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (828 aa)
UMAG_01599Uncharacterized protein. (309 aa)
UMAG_10870Glucose-6-phosphate 1-epimerase; Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P). (317 aa)
UMAG_01763DFDF domain-containing protein. (747 aa)
UMAG_02022Zn(2)-C6 fungal-type domain-containing protein. (862 aa)
UMAG_01014Thioredoxin domain-containing protein. (155 aa)
UMAG_06003Peptidyl-prolyl cis-trans isomerase. (174 aa)
UMAG_06058Chromosome 21, whole genome shotgun sequence. (468 aa)
UMAG_05352Chromosome 19, whole genome shotgun sequence. (537 aa)
UMAG_15066Chromosome 19, whole genome shotgun sequence. (1165 aa)
UMAG_04703Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (271 aa)
UMAG_04739Uncharacterized protein. (330 aa)
UMAG_05002Chromosome 15, whole genome shotgun sequence. (320 aa)
UMAG_04838Putative isopentenyl-diphosphate delta-isomerase. (262 aa)
UMAG_04983Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. (559 aa)
UMAG_11022Uncharacterized protein. (442 aa)
UMAG_15008Glucose-6-phosphate isomerase; Belongs to the GPI family. (469 aa)
UMAG_11054Peptidylprolyl isomerase. (113 aa)
UMAG_05416Chromosome 19, whole genome shotgun sequence. (615 aa)
UMAG_03726Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
CMU1Secreted chorismate mutase; Secreted chorismate mutase that is one component of a cocktail of effectors shaping the host metabolome and acting as virulence factors. The enzyme is taken up by plant cells, can spread to neighboring cells where it affects the biosynthesis of the plant immune signal salicylic acid by channelling chorismate into the phenylpropanoid pathway. Interfers with the activity of host cytosolic chorismate mutase CM2 through heterodimerization. (290 aa)
UMAG_03501DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1518 aa)
UMAG_10982Chromosome 8, whole genome shotgun sequence. (139 aa)
UMAG_03103Chromosome 7, whole genome shotgun sequence. (161 aa)
UMAG_03299Triosephosphate isomerase. (248 aa)
UMAG_04220Chorismate mutase. (288 aa)
UMAG_04066Rad60-SLD_2 domain-containing protein. (212 aa)
UMAG_10079Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (716 aa)
UMAG_02797TPR_REGION domain-containing protein. (236 aa)
UMAG_10156Protein disulfide-isomerase. (501 aa)
UMAG_11778Uncharacterized protein. (443 aa)
UMAG_02974Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family. (574 aa)
UMAG_11882Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
UMAG_10627Triosephosphate isomerase. (281 aa)
UMAG_01935Putative methylglutaconyl-coa hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (316 aa)
UMAG_10248Uncharacterized protein. (438 aa)
UMAG_02097Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (318 aa)
UMAG_02115MR_MLE domain-containing protein. (501 aa)
UMAG_02308Uncharacterized protein. (589 aa)
UMAG_01718Glucosamine-6-phosphate isomerase. (291 aa)
UMAG_01853Uncharacterized protein. (312 aa)
UMAG_10271Uncharacterized protein. (365 aa)
UMAG_10273Uncharacterized protein. (283 aa)
UMAG_00685Chromosome 1, whole genome shotgun sequence. (496 aa)
UMAG_00043Chromosome 1, whole genome shotgun sequence. (1066 aa)
UMAG_00486Chromosome 1, whole genome shotgun sequence; Belongs to the phosphohexose mutase family. (552 aa)
CYP6Peptidyl-prolyl cis-trans isomerase-like 4; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (551 aa)
ERG2C-8 sterol isomerase; Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols. (241 aa)
TOP1DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus remo [...] (1019 aa)
UMAG_06287Bifunctional lycopene cyclase/phytoene synthase; Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase). (690 aa)
CPR6Peptidyl-prolyl cis-trans isomerase D; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (398 aa)
RRD1Serine/threonine-protein phosphatase 2A activator 1; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A- phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity). (487 aa)
CYP8Peptidyl-prolyl cis-trans isomerase-like 2; May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins. (582 aa)
RKI1Ribose-5-phosphate isomerase. (286 aa)
CYP3Peptidyl-prolyl cis-trans isomerase H; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (156 aa)
CWC27Peptidyl-prolyl isomerase CWC27; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (By similarity). Belongs to the cyclophilin-type PPIase family. CWC27 subfamily. (485 aa)
UMAG_10306NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (267 aa)
CYP10Peptidyl-prolyl cis-trans isomerase-like 3; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily. (168 aa)
RRD2Serine/threonine-protein phosphatase 2A activator 2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A- phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity). (457 aa)
fer4Enoyl-CoA isomerase/hydratase fer4; Enoyl-CoA isomerase/hydratase; part of the gene cluster that mediates the biosynthesis of siderophore ferrichrome A which is contributing to organismal virulence. The first step of ferrichrome A biosynthesis is performed by the HMG-CoA synthase hcs1 which catalyzes the generation of HMG-CoA and CoA using acetoacetyl-CoA and acetyl-CoA as substrates. The enoyl-CoA isomerase/hydratase fer4 then catalyzes the conversion of hcs1-produced HMG-CoA to methylglutaconyl- CoA. The acyltransferase fer5 then fuses the fer4- generated methylglutaconyl-CoA with si [...] (274 aa)
Your Current Organism:
Ustilago maydis
NCBI taxonomy Id: 237631
Other names: U. maydis 521, Ustilago maydis 521
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