STRINGSTRING
UMAG_04216 UMAG_04216 DBP2 DBP2 HTZ1 HTZ1 UMAG_02007 UMAG_02007 CCR4 CCR4 VTS1 VTS1 FEN1 FEN1 RAI1 RAI1 RAT1 RAT1 UMAG_00714 UMAG_00714 UMAG_00684 UMAG_00684 UMAG_11455 UMAG_11455 UMAG_12154 UMAG_12154 UMAG_11428 UMAG_11428 LSM5 LSM5 UMAG_15020 UMAG_15020 UMAG_11620 UMAG_11620 UMAG_01285 UMAG_01285 UMAG_01220 UMAG_01220 UMAG_00564 UMAG_00564 UMAG_01011 UMAG_01011 UMAG_00463 UMAG_00463 UMAG_00978 UMAG_00978 UMAG_00415 UMAG_00415 UMAG_00833 UMAG_00833 UMAG_00233 UMAG_00233 UMAG_01919 UMAG_01919 UMAG_00548 UMAG_00548 UMAG_00318 UMAG_00318 UMAG_12159 UMAG_12159 UMAG_00987 UMAG_00987 UMAG_10130 UMAG_10130 UMAG_01974 UMAG_01974 UMAG_11846 UMAG_11846 UMAG_10873 UMAG_10873 UMAG_02696 UMAG_02696 UMAG_10570 UMAG_10570 UMAG_02526 UMAG_02526 UMAG_01561 UMAG_01561 UMAG_01794 UMAG_01794 UMAG_10771 UMAG_10771 UMAG_10765 UMAG_10765 UMAG_11668 UMAG_11668 UMAG_03277 UMAG_03277 UMAG_03227 UMAG_03227 UMAG_05201 UMAG_05201 UMAG_02425 UMAG_02425 PAN3 PAN3 UMAG_10375 UMAG_10375 UMAG_02611 UMAG_02611 UMAG_03023 UMAG_03023 LSM1 LSM1 UMAG_12199 UMAG_12199 UMAG_04997 UMAG_04997 UMAG_03766 UMAG_03766 UMAG_03967 UMAG_03967 UMAG_04799 UMAG_04799 UMAG_03518 UMAG_03518 UMAG_03504 UMAG_03504 UMAG_03821 UMAG_03821 UMAG_10892 UMAG_10892 UMAG_04630 UMAG_04630 UMAG_04549 UMAG_04549 UMAG_12246 UMAG_12246 UMAG_06211 UMAG_06211 PAN2 PAN2 UMAG_06377 UMAG_06377 UMAG_05695 UMAG_05695 LSM4 LSM4 UMAG_04722 UMAG_04722 UMAG_10895 UMAG_10895 UMAG_05674 UMAG_05674 UMAG_04701 UMAG_04701 UMAG_05563 UMAG_05563 UMAG_05540 UMAG_05540 UMAG_06131 UMAG_06131 UMAG_10747 UMAG_10747 UMAG_11207 UMAG_11207 UMAG_06395 UMAG_06395 UMAG_15049 UMAG_15049 UMAG_00596 UMAG_00596 UMAG_00576 UMAG_00576 UMAG_00460 UMAG_00460 UMAG_00393 UMAG_00393 UMAG_01198 UMAG_01198 UMAG_01067 UMAG_01067 UMAG_10588 UMAG_10588 UMAG_01817 UMAG_01817 UMAG_01783 UMAG_01783 UMAG_11667 UMAG_11667 UMAG_10128 UMAG_10128 UMAG_02572 UMAG_02572 UMAG_03076 UMAG_03076 UMAG_11502 UMAG_11502 UMAG_03702 UMAG_03702 UMAG_11761 UMAG_11761 UMAG_04976 UMAG_04976 UMAG_05467 UMAG_05467 UMAG_05334 UMAG_05334 UMAG_00632 UMAG_00632 UMAG_10921 UMAG_10921 UMAG_10020 UMAG_10020 UMAG_01182 UMAG_01182 UMAG_11680 UMAG_11680 UMAG_02189 UMAG_02189 UMAG_02132 UMAG_02132 UMAG_02552 UMAG_02552 UMAG_10332 UMAG_10332 UMAG_10390 UMAG_10390 UMAG_03145 UMAG_03145 UMAG_03549 UMAG_03549 UMAG_03771 UMAG_03771 UMAG_12284 UMAG_12284 UMAG_11213 UMAG_11213 UMAG_05991 UMAG_05991
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UMAG_04216Chromosome 12, whole genome shotgun sequence. (965 aa)
DBP2ATP-dependent RNA helicase DBP2; ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing. (552 aa)
HTZ1Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] (135 aa)
UMAG_02007Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (193 aa)
CCR4Glucose-repressible alcohol dehydrogenase transcriptional effector; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity); Belongs to [...] (670 aa)
VTS1Protein VTS1; RNA-binding protein involved in post-transcriptional regulation through transcript degradation. May be involved in vacuolar protein transport (By similarity). (728 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (374 aa)
RAI1Decapping nuclease RAI1; Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and pyrophosphohydrolase activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity). Belongs to the DXO/Dom3Z family. (507 aa)
RAT15'-3' exoribonuclease 2; Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity); Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily. (1233 aa)
UMAG_00714Chromosome 1, whole genome shotgun sequence. (731 aa)
UMAG_00684Chromosome 1, whole genome shotgun sequence. (531 aa)
UMAG_11455Chromosome 1, whole genome shotgun sequence. (600 aa)
UMAG_12154Chromosome 1, whole genome shotgun sequence. (1560 aa)
UMAG_11428Chromosome 1, whole genome shotgun sequence. (1094 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (103 aa)
UMAG_15020Chromosome 1, whole genome shotgun sequence. (209 aa)
UMAG_11620Chromosome 1, whole genome shotgun sequence. (260 aa)
UMAG_01285Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (230 aa)
UMAG_01220DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. (1404 aa)
UMAG_00564Chromosome 1, whole genome shotgun sequence. (368 aa)
UMAG_01011DBR1 domain-containing protein. (569 aa)
UMAG_00463Chromosome 1, whole genome shotgun sequence. (729 aa)
UMAG_00978Putative exosome complex exonuclease. (327 aa)
UMAG_00415Chromosome 1, whole genome shotgun sequence. (1652 aa)
UMAG_00833Putative proteasome regulatory particle base subunit RPT6; Belongs to the AAA ATPase family. (424 aa)
UMAG_00233Chromosome 1, whole genome shotgun sequence. (559 aa)
UMAG_01919Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (185 aa)
UMAG_00548Chromosome 1, whole genome shotgun sequence; Belongs to the GDA1/CD39 NTPase family. (646 aa)
UMAG_00318Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (315 aa)
UMAG_12159Uncharacterized protein. (1438 aa)
UMAG_00987Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (974 aa)
UMAG_10130Uncharacterized protein. (919 aa)
UMAG_01974Uncharacterized protein. (1014 aa)
UMAG_11846IU_nuc_hydro domain-containing protein. (580 aa)
UMAG_10873Uncharacterized protein. (356 aa)
UMAG_02696Uncharacterized protein. (1034 aa)
UMAG_10570Uncharacterized protein. (802 aa)
UMAG_02526Uncharacterized protein. (275 aa)
UMAG_01561Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (430 aa)
UMAG_01794A_deaminase domain-containing protein. (571 aa)
UMAG_10771Uncharacterized protein. (278 aa)
UMAG_10765Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (343 aa)
UMAG_11668Uncharacterized protein. (1058 aa)
UMAG_03277Chromosome 8, whole genome shotgun sequence. (1044 aa)
UMAG_03227Chromosome 8, whole genome shotgun sequence. (273 aa)
UMAG_05201ERCC4 domain-containing protein. (846 aa)
UMAG_02425Putative CCR4-NOT core exoribonuclease subunit protein. (316 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (866 aa)
UMAG_10375Chromosome 7, whole genome shotgun sequence. (514 aa)
UMAG_02611Uncharacterized protein; Belongs to the RNase T2 family. (271 aa)
UMAG_03023Chromosome 7, whole genome shotgun sequence; Belongs to the RNase T2 family. (297 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (148 aa)
UMAG_12199Chromosome 7, whole genome shotgun sequence. (410 aa)
UMAG_04997Chromosome 15, whole genome shotgun sequence. (891 aa)
UMAG_03766Chromosome 10, whole genome shotgun sequence. (559 aa)
UMAG_03967PAT1 domain-containing protein. (920 aa)
UMAG_04799Mago-bind domain-containing protein. (251 aa)
UMAG_03518Chromosome 9, whole genome shotgun sequence. (1206 aa)
UMAG_03504Chromosome 9, whole genome shotgun sequence. (330 aa)
UMAG_03821Chromosome 10, whole genome shotgun sequence. (692 aa)
UMAG_10892Chromosome 12, whole genome shotgun sequence. (335 aa)
UMAG_04630ERCC4 domain-containing protein. (605 aa)
UMAG_04549RNase_PH domain-containing protein. (297 aa)
UMAG_12246Nudix hydrolase domain-containing protein. (308 aa)
UMAG_06211Uncharacterized protein. (1010 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1444 aa)
UMAG_06377Chromosome 23, whole genome shotgun sequence; Belongs to the eukaryotic initiation factor 4E family. (280 aa)
UMAG_05695Chromosome 16, whole genome shotgun sequence. (755 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (146 aa)
UMAG_04722RPOL4c domain-containing protein. (175 aa)
UMAG_10895Uncharacterized protein. (523 aa)
UMAG_05674Endonuclease. (364 aa)
UMAG_04701Putative rcd1 protein involved in sexual development. (428 aa)
UMAG_05563CULLIN_2 domain-containing protein; Belongs to the cullin family. (822 aa)
UMAG_05540Uncharacterized protein. (2118 aa)
UMAG_06131Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (551 aa)
UMAG_10747RNase_PH domain-containing protein. (302 aa)
UMAG_11207Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (323 aa)
UMAG_06395Chromosome 23, whole genome shotgun sequence. (735 aa)
UMAG_15049Chromosome 1, whole genome shotgun sequence. (1007 aa)
UMAG_00596Chromosome 1, whole genome shotgun sequence. (917 aa)
UMAG_00576Chromosome 1, whole genome shotgun sequence. (237 aa)
UMAG_00460Chromosome 1, whole genome shotgun sequence. (379 aa)
UMAG_00393Chromosome 1, whole genome shotgun sequence. (1301 aa)
UMAG_01198Uncharacterized protein. (281 aa)
UMAG_010675'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1478 aa)
UMAG_10588Nudix hydrolase domain-containing protein. (825 aa)
UMAG_01817Uncharacterized protein. (223 aa)
UMAG_01783IU_nuc_hydro domain-containing protein. (426 aa)
UMAG_11667Putative ATP-dependent RNA helicase MTR4. (1124 aa)
UMAG_10128Sm domain-containing protein. (147 aa)
UMAG_02572Uncharacterized protein. (426 aa)
UMAG_03076Chromosome 7, whole genome shotgun sequence. (643 aa)
UMAG_11502Chromosome 7, whole genome shotgun sequence. (206 aa)
UMAG_03702Chromosome 10, whole genome shotgun sequence; Belongs to the RNR ribonuclease family. (1012 aa)
UMAG_11761KH_dom_type_1 domain-containing protein. (401 aa)
UMAG_04976Chromosome 15, whole genome shotgun sequence. (510 aa)
UMAG_05467PUM-HD domain-containing protein. (748 aa)
UMAG_05334Chromosome 19, whole genome shotgun sequence. (170 aa)
UMAG_00632Chromosome 1, whole genome shotgun sequence. (301 aa)
UMAG_10921Chromosome 1, whole genome shotgun sequence. (828 aa)
UMAG_10020Chromosome 1, whole genome shotgun sequence. (857 aa)
UMAG_01182Uncharacterized protein. (442 aa)
UMAG_11680Sec39 domain-containing protein. (1046 aa)
UMAG_02189Putative 3-hydroxyisobutyrate dehydrogenase. (366 aa)
UMAG_02132Uncharacterized protein. (268 aa)
UMAG_02552Uncharacterized protein. (1336 aa)
UMAG_10332Chromosome 7, whole genome shotgun sequence. (539 aa)
UMAG_10390Chromosome 8, whole genome shotgun sequence. (332 aa)
UMAG_03145Chromosome 8, whole genome shotgun sequence. (332 aa)
UMAG_03549Chromosome 9, whole genome shotgun sequence. (1235 aa)
UMAG_03771Chromosome 10, whole genome shotgun sequence. (738 aa)
UMAG_12284Nuclear cap-binding protein subunit 2. (268 aa)
UMAG_11213Chromosome 21, whole genome shotgun sequence. (1036 aa)
UMAG_05991Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (667 aa)
Your Current Organism:
Ustilago maydis
NCBI taxonomy Id: 237631
Other names: U. maydis 521, Ustilago maydis 521
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