STRINGSTRING
UMAG_06087 UMAG_06087 UMAG_05262 UMAG_05262 UMAG_05376 UMAG_05376 UMAG_10347 UMAG_10347 UMAG_04820 UMAG_04820 UMAG_05029 UMAG_05029 UMAG_10910 UMAG_10910 UMAG_04603 UMAG_04603 UMAG_04230 UMAG_04230 UMAG_04013 UMAG_04013 UMAG_03792 UMAG_03792 UMAG_11008 UMAG_11008 UMAG_02823 UMAG_02823 UMAG_02543 UMAG_02543 UMAG_11663 UMAG_11663 UMAG_00983 UMAG_00983 UMAG_01122 UMAG_01122 UMAG_11308 UMAG_11308 UMAG_10101 UMAG_10101 UMAG_11355 UMAG_11355 UMAG_00439 UMAG_00439 UMAG_00575 UMAG_00575 UMAG_05557 UMAG_05557 UMAG_04976 UMAG_04976 UMAG_03875 UMAG_03875 UMAG_03979 UMAG_03979 UMAG_03984 UMAG_03984 UMAG_03743 UMAG_03743 UMAG_03772 UMAG_03772 UMAG_11959 UMAG_11959 UMAG_03244 UMAG_03244 UMAG_10656 UMAG_10656 UMAG_02591 UMAG_02591 UMAG_02605 UMAG_02605 UMAG_02775 UMAG_02775 UMAG_12182 UMAG_12182 UMAG_10071 UMAG_10071 UMAG_02311 UMAG_02311 UMAG_05156 UMAG_05156 UMAG_05210 UMAG_05210 UMAG_01458 UMAG_01458 UMAG_01883 UMAG_01883 UMAG_11301 UMAG_11301 UMAG_11302 UMAG_11302 UMAG_00620 UMAG_00620 UMAG_00625 UMAG_00625 UMAG_11828 UMAG_11828 UMAG_00706 UMAG_00706 UMAG_06037 UMAG_06037 UMAG_04812 UMAG_04812 UMAG_10752 UMAG_10752 UMAG_04927 UMAG_04927 UMAG_04785 UMAG_04785 UMAG_10848 UMAG_10848 UMAG_04381 UMAG_04381 UMAG_04389 UMAG_04389 UMAG_06358 UMAG_06358 UMAG_06410 UMAG_06410 UMAG_11545 UMAG_11545 UMAG_04529 UMAG_04529 UMAG_03740 UMAG_03740 UMAG_11575 UMAG_11575 UMAG_04165 UMAG_04165 UMAG_04180 UMAG_04180 UMAG_03806 UMAG_03806 UMAG_04234 UMAG_04234 UMAG_10352 UMAG_10352 UMAG_15099 UMAG_15099 UMAG_03513 UMAG_03513 UMAG_10833 UMAG_10833 UMAG_03766 UMAG_03766 UMAG_12227 UMAG_12227 UMAG_03852 UMAG_03852 UMAG_04390 UMAG_04390 UMAG_03501 UMAG_03501 UMAG_02958 UMAG_02958 UMAG_03288 UMAG_03288 UMAG_02557 UMAG_02557 UMAG_04206 UMAG_04206 UMAG_02606 UMAG_02606 UMAG_02863 UMAG_02863 UMAG_11490 UMAG_11490 UMAG_02760 UMAG_02760 UMAG_03001 UMAG_03001 UMAG_03779 UMAG_03779 UMAG_12243 UMAG_12243 UMAG_10135 UMAG_10135 UMAG_02065 UMAG_02065 UMAG_02102 UMAG_02102 UMAG_02221 UMAG_02221 UMAG_05118 UMAG_05118 UMAG_10645 UMAG_10645 UMAG_11881 UMAG_11881 UMAG_06299 UMAG_06299 UMAG_10318 UMAG_10318 UMAG_01866 UMAG_01866 UMAG_01646 UMAG_01646 UMAG_02579 UMAG_02579 UMAG_02607 UMAG_02607 UMAG_10570 UMAG_10570 UMAG_11717 UMAG_11717 UMAG_01961 UMAG_01961 UMAG_00995 UMAG_00995 UMAG_12116 UMAG_12116 UMAG_02462 UMAG_02462 UMAG_05089 UMAG_05089 UMAG_01191 UMAG_01191 UMAG_06271 UMAG_06271 UMAG_01577 UMAG_01577 UMAG_00172 UMAG_00172 UMAG_00592 UMAG_00592 UMAG_00754 UMAG_00754 UMAG_10100 UMAG_10100 UMAG_00428 UMAG_00428 UMAG_01027 UMAG_01027 UMAG_11652 UMAG_11652 UMAG_00527 UMAG_00527 UMAG_00728 UMAG_00728 REC1 REC1 UMAG_05207 UMAG_05207 RVB1 RVB1 ARP4 ARP4 SPT16 SPT16 SWR1 SWR1 HAT2 HAT2 SMU1 SMU1 POB3 POB3 SWC5 SWC5 RVB2 RVB2 EAF3 EAF3 TOF1 TOF1 SET2 SET2 SLX1 SLX1 YAF9 YAF9 POL2 POL2 SWC4 SWC4 INO80 INO80 RAD51 RAD51
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UMAG_06087Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (980 aa)
UMAG_05262Chromosome 19, whole genome shotgun sequence. (1059 aa)
UMAG_05376Chromosome 19, whole genome shotgun sequence. (982 aa)
UMAG_10347Uncharacterized protein; Belongs to the actin family. (813 aa)
UMAG_04820Uncharacterized protein. (1009 aa)
UMAG_05029Chromosome 15, whole genome shotgun sequence; Belongs to the actin family. (544 aa)
UMAG_10910Uncharacterized protein. (381 aa)
UMAG_04603Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (918 aa)
UMAG_04230Chromosome 12, whole genome shotgun sequence. (2115 aa)
UMAG_04013PAPA-1 domain-containing protein. (545 aa)
UMAG_03792Chromosome 10, whole genome shotgun sequence. (1191 aa)
UMAG_11008Chromosome 8, whole genome shotgun sequence. (1265 aa)
UMAG_02823Chromosome 7, whole genome shotgun sequence. (1104 aa)
UMAG_02543Uncharacterized protein. (869 aa)
UMAG_11663Uncharacterized protein. (670 aa)
UMAG_00983SANT domain-containing protein. (2193 aa)
UMAG_01122AAA domain-containing protein. (847 aa)
UMAG_11308Histone deacetylase. (585 aa)
UMAG_10101Chromosome 1, whole genome shotgun sequence. (610 aa)
UMAG_11355Chromosome 1, whole genome shotgun sequence. (79 aa)
UMAG_00439Chromosome 1, whole genome shotgun sequence. (323 aa)
UMAG_00575Chromosome 1, whole genome shotgun sequence. (882 aa)
UMAG_05557Uncharacterized protein. (976 aa)
UMAG_04976Chromosome 15, whole genome shotgun sequence. (510 aa)
UMAG_03875Uncharacterized protein. (82 aa)
UMAG_03979Nudix hydrolase domain-containing protein. (543 aa)
UMAG_03984PolyA_pol domain-containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (713 aa)
UMAG_03743Chromosome 10, whole genome shotgun sequence; Belongs to the actin family. (732 aa)
UMAG_03772Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (553 aa)
UMAG_11959Chromosome 9, whole genome shotgun sequence. (157 aa)
UMAG_03244Chromatin modification-related protein. (732 aa)
UMAG_10656DNA primase; Belongs to the eukaryotic-type primase small subunit family. (492 aa)
UMAG_02591Uncharacterized protein. (730 aa)
UMAG_02605PHD domain-containing protein. (1084 aa)
UMAG_02775NDT80 domain-containing protein. (919 aa)
UMAG_12182Uncharacterized protein. (342 aa)
UMAG_10071Uncharacterized protein. (216 aa)
UMAG_02311PHD domain-containing protein. (1100 aa)
UMAG_05156Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (623 aa)
UMAG_05210Uncharacterized protein. (321 aa)
UMAG_01458DNA polymerase. (1057 aa)
UMAG_01883Uncharacterized protein. (232 aa)
UMAG_11301Putative SWI/SNF catalytic subunit. (1506 aa)
UMAG_11302Chromatin modification-related protein. (538 aa)
UMAG_00620Chromosome 1, whole genome shotgun sequence. (175 aa)
UMAG_00625Chromosome 1, whole genome shotgun sequence. (997 aa)
UMAG_11828Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (442 aa)
UMAG_00706Chromosome 1, whole genome shotgun sequence. (1436 aa)
UMAG_06037Chromosome 21, whole genome shotgun sequence. (653 aa)
UMAG_04812ARID domain-containing protein. (1652 aa)
UMAG_10752Uncharacterized protein. (141 aa)
UMAG_04927Chromosome 15, whole genome shotgun sequence. (219 aa)
UMAG_04785Checkpoint protein; Belongs to the HUS1 family. (285 aa)
UMAG_10848Uncharacterized protein. (645 aa)
UMAG_04381Uncharacterized protein. (2080 aa)
UMAG_04389Structural maintenance of chromosomes protein. (1218 aa)
UMAG_06358Chromosome 23, whole genome shotgun sequence. (867 aa)
UMAG_06410Chromosome 23, whole genome shotgun sequence. (796 aa)
UMAG_11545YL1_C domain-containing protein. (199 aa)
UMAG_04529DNA polymerase. (1667 aa)
UMAG_03740Chromosome 10, whole genome shotgun sequence. (1250 aa)
UMAG_11575Uncharacterized protein. (247 aa)
UMAG_04165Chromosome 12, whole genome shotgun sequence. (114 aa)
UMAG_04180Chromosome 12, whole genome shotgun sequence. (417 aa)
UMAG_03806Chromosome 10, whole genome shotgun sequence. (336 aa)
UMAG_04234Chromosome 12, whole genome shotgun sequence. (568 aa)
UMAG_10352Uncharacterized protein. (333 aa)
UMAG_15099Uncharacterized protein. (656 aa)
UMAG_03513Chromosome 9, whole genome shotgun sequence. (274 aa)
UMAG_10833Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1159 aa)
UMAG_03766Chromosome 10, whole genome shotgun sequence. (559 aa)
UMAG_12227Chromosome 8, whole genome shotgun sequence. (211 aa)
UMAG_03852DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (543 aa)
UMAG_04390RRM domain-containing protein. (390 aa)
UMAG_03501DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1518 aa)
UMAG_02958Chromosome 7, whole genome shotgun sequence. (846 aa)
UMAG_03288Chromosome 8, whole genome shotgun sequence. (249 aa)
UMAG_02557DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (764 aa)
UMAG_04206Chromosome 12, whole genome shotgun sequence. (1601 aa)
UMAG_02606Telomere_reg-2 domain-containing protein. (1135 aa)
UMAG_02863Chromosome 7, whole genome shotgun sequence. (864 aa)
UMAG_11490Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (732 aa)
UMAG_02760DNA_pol_E_B domain-containing protein. (632 aa)
UMAG_03001Chromosome 7, whole genome shotgun sequence. (887 aa)
UMAG_03779Chromosome 10, whole genome shotgun sequence. (360 aa)
UMAG_12243Chromosome 10, whole genome shotgun sequence. (1081 aa)
UMAG_10135Zf-primase domain-containing protein. (1006 aa)
UMAG_02065Histone deacetylase. (569 aa)
UMAG_02102Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (727 aa)
UMAG_02221Aa_trans domain-containing protein. (523 aa)
UMAG_05118zf-4CXXC_R1 domain-containing protein. (1020 aa)
UMAG_10645Chromosome 8, whole genome shotgun sequence. (1027 aa)
UMAG_11881PHD-type domain-containing protein. (1182 aa)
UMAG_06299MRC1 domain-containing protein. (2004 aa)
UMAG_10318Chromosome 7, whole genome shotgun sequence. (351 aa)
UMAG_01866Uncharacterized protein. (200 aa)
UMAG_01646DNA helicase; Belongs to the MCM family. (1020 aa)
UMAG_02579Uncharacterized protein. (285 aa)
UMAG_02607Putative chromatin remodeling complex ATPase subunit. (1108 aa)
UMAG_10570Uncharacterized protein. (802 aa)
UMAG_11717HDAC_interact domain-containing protein. (1461 aa)
UMAG_01961Zn(2)-C6 fungal-type domain-containing protein. (894 aa)
UMAG_00995Uncharacterized protein. (773 aa)
UMAG_12116ARID domain-containing protein. (1332 aa)
UMAG_02462Zn(2)-C6 fungal-type domain-containing protein. (1561 aa)
UMAG_05089GFA domain-containing protein. (233 aa)
UMAG_01191Uncharacterized protein. (630 aa)
UMAG_06271Uncharacterized protein. (456 aa)
UMAG_01577WD_REPEATS_REGION domain-containing protein. (369 aa)
UMAG_00172Chromosome 1, whole genome shotgun sequence. (647 aa)
UMAG_00592Chromosome 1, whole genome shotgun sequence. (869 aa)
UMAG_00754Chromosome 1, whole genome shotgun sequence. (166 aa)
UMAG_10100Chromosome 1, whole genome shotgun sequence. (215 aa)
UMAG_00428Chromosome 1, whole genome shotgun sequence. (294 aa)
UMAG_01027Uncharacterized protein. (734 aa)
UMAG_11652Sld5 domain-containing protein. (303 aa)
UMAG_00527Chromosome 1, whole genome shotgun sequence. (170 aa)
UMAG_00728Chromosome 1, whole genome shotgun sequence. (706 aa)
REC1DNA repair exonuclease REC1; Plays a central role in regulating the genetic system of this fungus. Has a 3'-->5' exonuclease activity. Belongs to the rad1 family. (463 aa)
UMAG_05207CBFD_NFYB_HMF domain-containing protein. (250 aa)
RVB1RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (488 aa)
ARP4Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes [...] (534 aa)
SPT16FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1032 aa)
SWR1Helicase SWR1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1830 aa)
HAT2Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. (433 aa)
SMU1Serine/threonine-protein kinase SMU1; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (746 aa)
POB3FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (558 aa)
SWC5SWR1-complex protein 5; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (354 aa)
RVB2RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (476 aa)
EAF3Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (330 aa)
TOF1Topoisomerase 1-associated factor 1; Involved in chromosome segregation during meiosis and DNA damage repair; Belongs to the timeless family. (1251 aa)
SET2Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (972 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (658 aa)
YAF9Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). (431 aa)
POL2DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication. (2305 aa)
SWC4SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (615 aa)
INO80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1910 aa)
RAD51DNA repair protein RAD51; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (339 aa)
Your Current Organism:
Ustilago maydis
NCBI taxonomy Id: 237631
Other names: U. maydis 521, Ustilago maydis 521
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