STRINGSTRING
UMAG_00963 UMAG_00963 UMAG_00983 UMAG_00983 UMAG_11308 UMAG_11308 UMAG_00439 UMAG_00439 UMAG_10463 UMAG_10463 UMAG_00575 UMAG_00575 UMAG_05557 UMAG_05557 UMAG_03984 UMAG_03984 UMAG_03743 UMAG_03743 UMAG_03244 UMAG_03244 UMAG_02605 UMAG_02605 UMAG_10071 UMAG_10071 UMAG_02311 UMAG_02311 UMAG_05166 UMAG_05166 UMAG_01523 UMAG_01523 UMAG_01883 UMAG_01883 UMAG_11301 UMAG_11301 UMAG_10546 UMAG_10546 UMAG_05262 UMAG_05262 UMAG_05376 UMAG_05376 UMAG_10347 UMAG_10347 UMAG_04820 UMAG_04820 UMAG_05626 UMAG_05626 UMAG_05029 UMAG_05029 UMAG_04603 UMAG_04603 UMAG_04013 UMAG_04013 UMAG_11779 UMAG_11779 UMAG_11663 UMAG_11663 UMAG_01577 UMAG_01577 UMAG_00451 UMAG_00451 UMAG_01853 UMAG_01853 UMAG_11438 UMAG_11438 UMAG_00592 UMAG_00592 UMAG_00750 UMAG_00750 UMAG_00754 UMAG_00754 UMAG_01027 UMAG_01027 UMAG_01030 UMAG_01030 UMAG_11281 UMAG_11281 UMAG_00775 UMAG_00775 CYP6 CYP6 URBS1 URBS1 UMAG_05207 UMAG_05207 RVB1 RVB1 ARP4 ARP4 SPT16 SPT16 SWR1 SWR1 ESA1 ESA1 BRE1 BRE1 HAT2 HAT2 POB3 POB3 SWC5 SWC5 RVB2 RVB2 HHT1 HHT1 EAF3 EAF3 HHT2 HHT2 SET2 SET2 SET5 SET5 HTB1 HTB1 HTA1 HTA1 UBC2 UBC2 YAF9 YAF9 SWC4 SWC4 INO80 INO80 UMAG_00675 UMAG_00675 HTZ1 HTZ1 SPT6 SPT6 HHF1 HHF1 UMAG_11302 UMAG_11302 UMAG_11342 UMAG_11342 UMAG_11828 UMAG_11828 UMAG_00706 UMAG_00706 UMAG_11808 UMAG_11808 UMAG_06037 UMAG_06037 UMAG_05862 UMAG_05862 UMAG_04812 UMAG_04812 UMAG_04381 UMAG_04381 UMAG_06410 UMAG_06410 UMAG_11545 UMAG_11545 UMAG_10429 UMAG_10429 UMAG_11575 UMAG_11575 UMAG_04234 UMAG_04234 UMAG_15099 UMAG_15099 UMAG_10833 UMAG_10833 UMAG_12222 UMAG_12222 UMAG_04928 UMAG_04928 UMAG_03379 UMAG_03379 UMAG_02958 UMAG_02958 UMAG_03288 UMAG_03288 UMAG_04206 UMAG_04206 UMAG_02582 UMAG_02582 UMAG_04260 UMAG_04260 UMAG_02606 UMAG_02606 UMAG_02622 UMAG_02622 UMAG_11713 UMAG_11713 UMAG_12243 UMAG_12243 UMAG_02065 UMAG_02065 UMAG_02102 UMAG_02102 UMAG_02478 UMAG_02478 UMAG_10645 UMAG_10645 UMAG_11881 UMAG_11881 UMAG_05141 UMAG_05141 UMAG_01646 UMAG_01646 UMAG_02607 UMAG_02607 UMAG_10570 UMAG_10570 UMAG_11717 UMAG_11717 UMAG_01961 UMAG_01961 UMAG_12116 UMAG_12116 UMAG_02462 UMAG_02462 UMAG_05089 UMAG_05089 UMAG_06280 UMAG_06280
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UMAG_00963Deacetylase sirtuin-type domain-containing protein. (596 aa)
UMAG_00983SANT domain-containing protein. (2193 aa)
UMAG_11308Histone deacetylase. (585 aa)
UMAG_00439Chromosome 1, whole genome shotgun sequence. (323 aa)
UMAG_10463Chromosome 1, whole genome shotgun sequence. (623 aa)
UMAG_00575Chromosome 1, whole genome shotgun sequence. (882 aa)
UMAG_05557Uncharacterized protein. (976 aa)
UMAG_03984PolyA_pol domain-containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (713 aa)
UMAG_03743Chromosome 10, whole genome shotgun sequence; Belongs to the actin family. (732 aa)
UMAG_03244Chromatin modification-related protein. (732 aa)
UMAG_02605PHD domain-containing protein. (1084 aa)
UMAG_10071Uncharacterized protein. (216 aa)
UMAG_02311PHD domain-containing protein. (1100 aa)
UMAG_05166Uncharacterized protein. (1106 aa)
UMAG_01523Forkhead transcription factor required for pathogenic development. (439 aa)
UMAG_01883Uncharacterized protein. (232 aa)
UMAG_11301Putative SWI/SNF catalytic subunit. (1506 aa)
UMAG_10546Chromosome 19, whole genome shotgun sequence. (184 aa)
UMAG_05262Chromosome 19, whole genome shotgun sequence. (1059 aa)
UMAG_05376Chromosome 19, whole genome shotgun sequence. (982 aa)
UMAG_10347Uncharacterized protein; Belongs to the actin family. (813 aa)
UMAG_04820Uncharacterized protein. (1009 aa)
UMAG_05626Chromosome 16, whole genome shotgun sequence. (292 aa)
UMAG_05029Chromosome 15, whole genome shotgun sequence; Belongs to the actin family. (544 aa)
UMAG_04603Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (918 aa)
UMAG_04013PAPA-1 domain-containing protein. (545 aa)
UMAG_11779Putative transcriptional regulator. (1721 aa)
UMAG_11663Uncharacterized protein. (670 aa)
UMAG_01577WD_REPEATS_REGION domain-containing protein. (369 aa)
UMAG_00451Chromosome 1, whole genome shotgun sequence. (240 aa)
UMAG_01853Uncharacterized protein. (312 aa)
UMAG_11438Chromosome 1, whole genome shotgun sequence. (535 aa)
UMAG_00592Chromosome 1, whole genome shotgun sequence. (869 aa)
UMAG_00750Chromosome 1, whole genome shotgun sequence. (613 aa)
UMAG_00754Chromosome 1, whole genome shotgun sequence. (166 aa)
UMAG_01027Uncharacterized protein. (734 aa)
UMAG_01030Uncharacterized protein. (606 aa)
UMAG_11281Putative DEAH-box ATP-dependent RNA helicase PRP43. (784 aa)
UMAG_00775Chromosome 1, whole genome shotgun sequence. (904 aa)
CYP6Peptidyl-prolyl cis-trans isomerase-like 4; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (551 aa)
URBS1Siderophore biosynthesis regulatory protein URBS1; Involved in the regulation of secreted ferrichrome-type siderophores. Acts directly or indirectly to repress the biosynthesis of siderophores. (1084 aa)
UMAG_05207CBFD_NFYB_HMF domain-containing protein. (250 aa)
RVB1RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (488 aa)
ARP4Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes [...] (534 aa)
SPT16FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1032 aa)
SWR1Helicase SWR1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1830 aa)
ESA1Histone acetyltransferase ESA1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double-strand break repair through homologous recombination. Involved in cell cycle progression. Recruitment to promoters depends on [...] (565 aa)
BRE1E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. (817 aa)
HAT2Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. (433 aa)
POB3FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (558 aa)
SWC5SWR1-complex protein 5; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (354 aa)
RVB2RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (476 aa)
HHT1Histone H3.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
EAF3Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (330 aa)
HHT2Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
SET2Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (972 aa)
SET5Potential protein lysine methyltransferase SET5; Putative protein lysine methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily. (498 aa)
HTB1Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (142 aa)
HTA1Histone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
UBC2Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
YAF9Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). (431 aa)
SWC4SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (615 aa)
INO80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1910 aa)
UMAG_00675DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (637 aa)
HTZ1Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] (135 aa)
SPT6Transcription elongation factor SPT6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity); Belongs to the SPT6 family. (1723 aa)
HHF1Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
UMAG_11302Chromatin modification-related protein. (538 aa)
UMAG_11342Chromosome 1, whole genome shotgun sequence. (349 aa)
UMAG_11828Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (442 aa)
UMAG_00706Chromosome 1, whole genome shotgun sequence. (1436 aa)
UMAG_11808Chromosome 21, whole genome shotgun sequence. (683 aa)
UMAG_06037Chromosome 21, whole genome shotgun sequence. (653 aa)
UMAG_05862Uncharacterized protein. (1094 aa)
UMAG_04812ARID domain-containing protein. (1652 aa)
UMAG_04381Uncharacterized protein. (2080 aa)
UMAG_06410Chromosome 23, whole genome shotgun sequence. (796 aa)
UMAG_11545YL1_C domain-containing protein. (199 aa)
UMAG_10429DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1241 aa)
UMAG_11575Uncharacterized protein. (247 aa)
UMAG_04234Chromosome 12, whole genome shotgun sequence. (568 aa)
UMAG_15099Uncharacterized protein. (656 aa)
UMAG_10833Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1159 aa)
UMAG_12222Chromosome 8, whole genome shotgun sequence. (706 aa)
UMAG_04928Chromosome 15, whole genome shotgun sequence. (1084 aa)
UMAG_03379Chromosome 8, whole genome shotgun sequence. (716 aa)
UMAG_02958Chromosome 7, whole genome shotgun sequence. (846 aa)
UMAG_03288Chromosome 8, whole genome shotgun sequence. (249 aa)
UMAG_04206Chromosome 12, whole genome shotgun sequence. (1601 aa)
UMAG_02582Regulator Ustilago maydis 1 protein (Rum1). (2289 aa)
UMAG_04260Chromosome 12, whole genome shotgun sequence. (575 aa)
UMAG_02606Telomere_reg-2 domain-containing protein. (1135 aa)
UMAG_02622Uncharacterized protein. (279 aa)
UMAG_11713Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1411 aa)
UMAG_12243Chromosome 10, whole genome shotgun sequence. (1081 aa)
UMAG_02065Histone deacetylase. (569 aa)
UMAG_02102Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (727 aa)
UMAG_02478Uncharacterized protein. (790 aa)
UMAG_10645Chromosome 8, whole genome shotgun sequence. (1027 aa)
UMAG_11881PHD-type domain-containing protein. (1182 aa)
UMAG_05141UmuC domain-containing protein. (682 aa)
UMAG_01646DNA helicase; Belongs to the MCM family. (1020 aa)
UMAG_02607Putative chromatin remodeling complex ATPase subunit. (1108 aa)
UMAG_10570Uncharacterized protein. (802 aa)
UMAG_11717HDAC_interact domain-containing protein. (1461 aa)
UMAG_01961Zn(2)-C6 fungal-type domain-containing protein. (894 aa)
UMAG_12116ARID domain-containing protein. (1332 aa)
UMAG_02462Zn(2)-C6 fungal-type domain-containing protein. (1561 aa)
UMAG_05089GFA domain-containing protein. (233 aa)
UMAG_06280Uncharacterized protein. (1482 aa)
Your Current Organism:
Ustilago maydis
NCBI taxonomy Id: 237631
Other names: U. maydis 521, Ustilago maydis 521
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