(15 nodes) Tricarboxylic acid cycle enzyme complex network (Ustilago maydis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	UMAG_01904	Ligase_CoA domain-containing protein. (400 aa)
	UMAG_10599	Putative branched-chain alpha-keto acid dehydrogenase subunit e1-beta. (292 aa)
	UMAG_10533	Putative alpha-ketoglutarate dehydrogenase KGD1. (1039 aa)
	UMAG_11218	Uncharacterized protein. (126 aa)
	UMAG_00203	Chromosome 1, whole genome shotgun sequence. (395 aa)
	UMAG_01903	CoA_binding domain-containing protein. (357 aa)
	UMAG_10735	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (478 aa)
	UMAG_10804	Putative alpha-ketoglutarate dehydrogenase KGD2. (471 aa)
	UMAG_01329	Putative isocitrate dehydrogenase (NAD(+)) IDH1. (387 aa)
	UMAG_00407	Chromosome 1, whole genome shotgun sequence. (359 aa)
	UMAG_11353	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (426 aa)
	UMAG_10787	Chromosome 1, whole genome shotgun sequence. (512 aa)
	UMAG_01328	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
	UMAG_01672	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (330 aa)
	UMAG_02461	Dihydrolipoyl dehydrogenase. (508 aa)

Your Current Organism:

Ustilago maydis

NCBI taxonomy Id: 237631
Other names: U. maydis 521, Ustilago maydis 521

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
UMAG_00203	UMAG_00407	A0A0D1CZR4	A0A0D1E9F7	Chromosome 1, whole genome shotgun sequence.	Chromosome 1, whole genome shotgun sequence.	0.468
UMAG_00203	UMAG_01328	A0A0D1CZR4	A0A0D1E633	Chromosome 1, whole genome shotgun sequence.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.637
UMAG_00203	UMAG_01329	A0A0D1CZR4	A0A0D1EAL8	Chromosome 1, whole genome shotgun sequence.	Putative isocitrate dehydrogenase (NAD(+)) IDH1.	0.510
UMAG_00203	UMAG_01672	A0A0D1CZR4	A0A0D1E476	Chromosome 1, whole genome shotgun sequence.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.635
UMAG_00203	UMAG_01903	A0A0D1CZR4	A0A0D1CWH6	Chromosome 1, whole genome shotgun sequence.	CoA_binding domain-containing protein.	0.552
UMAG_00203	UMAG_01904	A0A0D1CZR4	A0A0D1E3R8	Chromosome 1, whole genome shotgun sequence.	Ligase_CoA domain-containing protein.	0.494
UMAG_00203	UMAG_02461	A0A0D1CZR4	A0A0D1E1C8	Chromosome 1, whole genome shotgun sequence.	Dihydrolipoyl dehydrogenase.	0.736
UMAG_00203	UMAG_10533	A0A0D1CZR4	A0A0D1DXV9	Chromosome 1, whole genome shotgun sequence.	Putative alpha-ketoglutarate dehydrogenase KGD1.	0.581
UMAG_00203	UMAG_10804	A0A0D1CZR4	A0A0D1CAI6	Chromosome 1, whole genome shotgun sequence.	Putative alpha-ketoglutarate dehydrogenase KGD2.	0.581
UMAG_00203	UMAG_11353	A0A0D1CZR4	A0A0D1E9A9	Chromosome 1, whole genome shotgun sequence.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.617
UMAG_00407	UMAG_00203	A0A0D1E9F7	A0A0D1CZR4	Chromosome 1, whole genome shotgun sequence.	Chromosome 1, whole genome shotgun sequence.	0.468
UMAG_00407	UMAG_01329	A0A0D1E9F7	A0A0D1EAL8	Chromosome 1, whole genome shotgun sequence.	Putative isocitrate dehydrogenase (NAD(+)) IDH1.	0.945
UMAG_00407	UMAG_01904	A0A0D1E9F7	A0A0D1E3R8	Chromosome 1, whole genome shotgun sequence.	Ligase_CoA domain-containing protein.	0.513
UMAG_00407	UMAG_02461	A0A0D1E9F7	A0A0D1E1C8	Chromosome 1, whole genome shotgun sequence.	Dihydrolipoyl dehydrogenase.	0.621
UMAG_00407	UMAG_10533	A0A0D1E9F7	A0A0D1DXV9	Chromosome 1, whole genome shotgun sequence.	Putative alpha-ketoglutarate dehydrogenase KGD1.	0.632
UMAG_00407	UMAG_10787	A0A0D1E9F7	A0A0D1E945	Chromosome 1, whole genome shotgun sequence.	Chromosome 1, whole genome shotgun sequence.	0.468
UMAG_00407	UMAG_10804	A0A0D1E9F7	A0A0D1CAI6	Chromosome 1, whole genome shotgun sequence.	Putative alpha-ketoglutarate dehydrogenase KGD2.	0.576
UMAG_00407	UMAG_11353	A0A0D1E9F7	A0A0D1E9A9	Chromosome 1, whole genome shotgun sequence.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.513
UMAG_01328	UMAG_00203	A0A0D1E633	A0A0D1CZR4	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Chromosome 1, whole genome shotgun sequence.	0.637
UMAG_01328	UMAG_01329	A0A0D1E633	A0A0D1EAL8	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Putative isocitrate dehydrogenase (NAD(+)) IDH1.	0.999