STRINGSTRING
RAD51 RAD51 UMAG_15027 UMAG_15027 UMAG_12318 UMAG_12318 UMAG_05381 UMAG_05381 UMAG_05408 UMAG_05408 UMAG_05459 UMAG_05459 UMAG_10347 UMAG_10347 UMAG_04704 UMAG_04704 UMAG_05626 UMAG_05626 UMAG_04989 UMAG_04989 UMAG_10529 UMAG_10529 UMAG_10901 UMAG_10901 UMAG_04603 UMAG_04603 UMAG_04151 UMAG_04151 UMAG_04212 UMAG_04212 UMAG_03863 UMAG_03863 UMAG_11008 UMAG_11008 UMAG_02565 UMAG_02565 UMAG_02712 UMAG_02712 UMAG_11929 UMAG_11929 UMAG_02056 UMAG_02056 UMAG_05228 UMAG_05228 UMAG_01864 UMAG_01864 UMAG_10616 UMAG_10616 UMAG_00920 UMAG_00920 UMAG_01110 UMAG_01110 UMAG_01262 UMAG_01262 UMAG_10235 UMAG_10235 UMAG_12076 UMAG_12076 UMAG_00290 UMAG_00290 UMAG_11196 UMAG_11196 UMAG_05891 UMAG_05891 UMAG_11451 UMAG_11451 UMAG_00691 UMAG_00691 UMAG_05334 UMAG_05334 UMAG_10751 UMAG_10751 UMAG_10917 UMAG_10917 UMAG_04460 UMAG_04460 UMAG_04669 UMAG_04669 UMAG_04136 UMAG_04136 UMAG_15011 UMAG_15011 UMAG_03886 UMAG_03886 UMAG_04069 UMAG_04069 UMAG_03777 UMAG_03777 UMAG_03434 UMAG_03434 UMAG_03550 UMAG_03550 UMAG_03141 UMAG_03141 UMAG_11009 UMAG_11009 UMAG_02874 UMAG_02874 UMAG_06506 UMAG_06506 UMAG_02371 UMAG_02371 UMAG_05117 UMAG_05117 UMAG_05151 UMAG_05151 UMAG_05156 UMAG_05156 UMAG_11783 UMAG_11783 UMAG_06296 UMAG_06296 UMAG_11392 UMAG_11392 UMAG_00848 UMAG_00848 UMAG_00989 UMAG_00989 UMAG_01394 UMAG_01394 UMAG_00669 UMAG_00669 UMAG_00817 UMAG_00817 UMAG_06213 UMAG_06213 UMAG_05939 UMAG_05939 UMAG_06219 UMAG_06219 UMAG_06000 UMAG_06000 UMAG_11580 UMAG_11580 UMAG_05846 UMAG_05846 UMAG_05563 UMAG_05563 UMAG_11798 UMAG_11798 UMAG_12032 UMAG_12032 UMAG_10551 UMAG_10551 UMAG_10936 UMAG_10936 UMAG_05569 UMAG_05569 UMAG_05574 UMAG_05574 UMAG_04902 UMAG_04902 UMAG_04722 UMAG_04722 UMAG_04367 UMAG_04367 UMAG_11157 UMAG_11157 UMAG_04623 UMAG_04623 UMAG_11545 UMAG_11545 UMAG_10429 UMAG_10429 UMAG_04391 UMAG_04391 UMAG_05845 UMAG_05845 UMAG_03898 UMAG_03898 UMAG_05888 UMAG_05888 UMAG_04630 UMAG_04630 UMAG_05403 UMAG_05403 UMAG_04165 UMAG_04165 UMAG_04202 UMAG_04202 UMAG_10352 UMAG_10352 UMAG_10359 UMAG_10359 UMAG_11521 UMAG_11521 UMAG_03565 UMAG_03565 UMAG_12288 UMAG_12288 UMAG_10396 UMAG_10396 UMAG_03766 UMAG_03766 UMAG_10845 UMAG_10845 UMAG_04344 UMAG_04344 UMAG_04442 UMAG_04442 UMAG_15013 UMAG_15013 UMAG_04588 UMAG_04588 UMAG_10982 UMAG_10982 UMAG_11946 UMAG_11946 UMAG_04129 UMAG_04129 UMAG_10658 UMAG_10658 NTH1 NTH1 UMAG_02817 UMAG_02817 UMAG_11475 UMAG_11475 UMAG_10433 UMAG_10433 UMAG_02863 UMAG_02863 UMAG_02911 UMAG_02911 UMAG_10322 UMAG_10322 UMAG_10604 UMAG_10604 UMAG_03001 UMAG_03001 UMAG_03025 UMAG_03025 UMAG_10486 UMAG_10486 UMAG_03689 UMAG_03689 UMAG_10286 UMAG_10286 UMAG_02639 UMAG_02639 UMAG_15061 UMAG_15061 UMAG_11928 UMAG_11928 UMAG_10512 UMAG_10512 UMAG_11724 UMAG_11724 UMAG_03394 UMAG_03394 UMAG_03491 UMAG_03491 UMAG_02324 UMAG_02324 UMAG_05118 UMAG_05118 UMAG_05201 UMAG_05201 UMAG_03200 UMAG_03200 UMAG_10830 UMAG_10830 UMAG_05085 UMAG_05085 UMAG_05141 UMAG_05141 UMAG_10198 UMAG_10198 UMAG_05208 UMAG_05208 UMAG_03095 UMAG_03095 UMAG_01931 UMAG_01931 UMAG_02579 UMAG_02579 UMAG_02607 UMAG_02607 UMAG_00869 UMAG_00869 UMAG_01729 UMAG_01729 UMAG_00907 UMAG_00907 UMAG_00922 UMAG_00922 UNG1 UNG1 UMAG_11911 UMAG_11911 UMAG_11304 UMAG_11304 UMAG_02211 UMAG_02211 UMAG_02220 UMAG_02220 UMAG_01293 UMAG_01293 UMAG_01085 UMAG_01085 UMAG_10194 UMAG_10194 UMAG_05197 UMAG_05197 UMAG_06265 UMAG_06265 UMAG_10774 UMAG_10774 UMAG_01304 UMAG_01304 UMAG_00216 UMAG_00216 UMAG_00282 UMAG_00282 UMAG_01421 UMAG_01421 UMAG_00077 UMAG_00077 UMAG_01742 UMAG_01742 UMAG_10027 UMAG_10027 UMAG_01790 UMAG_01790 UMAG_10261 UMAG_10261 UMAG_11420 UMAG_11420 UMAG_10922 UMAG_10922 UMAG_01932 UMAG_01932 UMAG_00447 UMAG_00447 UMAG_01185 UMAG_01185 UMAG_00599 UMAG_00599 UMAG_10923 UMAG_10923 UMAG_10924 UMAG_10924 UMAG_00729 UMAG_00729 UMAG_00101 UMAG_00101 UMAG_00376 UMAG_00376 UMAG_00527 UMAG_00527 CHK1 CHK1 UMAG_05207 UMAG_05207 CPR6 CPR6 RVB1 RVB1 ESA1 ESA1 MSH3 MSH3 SYF1 SYF1 RRI1 RRI1 TFB5 TFB5 TOF1 TOF1 SLX1 SLX1 HTB1 HTB1 ISY1 ISY1 UBC2 UBC2 INO80 INO80 UMAG_00675 UMAG_00675
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD51DNA repair protein RAD51; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (339 aa)
UMAG_15027Chromosome 21, whole genome shotgun sequence. (363 aa)
UMAG_12318Uncharacterized protein. (231 aa)
UMAG_05381Chromosome 19, whole genome shotgun sequence. (1346 aa)
UMAG_05408Chromosome 19, whole genome shotgun sequence; Belongs to the peptidase C19 family. (1198 aa)
UMAG_05459Uncharacterized protein. (117 aa)
UMAG_10347Uncharacterized protein; Belongs to the actin family. (813 aa)
UMAG_04704Mre11_DNA_bind domain-containing protein. (883 aa)
UMAG_05626Chromosome 16, whole genome shotgun sequence. (292 aa)
UMAG_04989Chromosome 15, whole genome shotgun sequence. (722 aa)
UMAG_10529Cyclin N-terminal domain-containing protein. (490 aa)
UMAG_10901Putative polyubiquitin. (228 aa)
UMAG_04603Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (918 aa)
UMAG_04151Chromosome 12, whole genome shotgun sequence. (850 aa)
UMAG_04212Chromosome 12, whole genome shotgun sequence. (1044 aa)
UMAG_03863DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1774 aa)
UMAG_11008Chromosome 8, whole genome shotgun sequence. (1265 aa)
UMAG_02565Integrase catalytic domain-containing protein. (493 aa)
UMAG_02712Uncharacterized protein. (683 aa)
UMAG_11929DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (986 aa)
UMAG_02056Uncharacterized protein. (253 aa)
UMAG_05228Uncharacterized protein. (447 aa)
UMAG_01864DRMBL domain-containing protein. (866 aa)
UMAG_10616Putative spindle pole body component, centrin. (196 aa)
UMAG_00920Putative DNA replication factor C subunit protein. (353 aa)
UMAG_01110Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2637 aa)
UMAG_01262Putative DNA polymerase X. (749 aa)
UMAG_10235Serine/threonine-protein phosphatase. (305 aa)
UMAG_12076Unplaced genomic scaffold um_scaf_contig_1.265, whole genome shotgun sequence. (376 aa)
UMAG_00290Chromosome 1, whole genome shotgun sequence. (1206 aa)
UMAG_11196DNA ligase. (851 aa)
UMAG_05891Uncharacterized protein. (337 aa)
UMAG_11451Chromosome 1, whole genome shotgun sequence. (354 aa)
UMAG_00691Chromosome 1, whole genome shotgun sequence. (873 aa)
UMAG_05334Chromosome 19, whole genome shotgun sequence. (170 aa)
UMAG_10751BSD domain-containing protein. (679 aa)
UMAG_10917Chromosome 16, whole genome shotgun sequence. (106 aa)
UMAG_04460DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (161 aa)
UMAG_04669DNA_LIGASE_A3 domain-containing protein. (1068 aa)
UMAG_04136Chromosome 12, whole genome shotgun sequence. (795 aa)
UMAG_15011Chromosome 12, whole genome shotgun sequence; Belongs to the PI3/PI4-kinase family. (3138 aa)
UMAG_03886Uncharacterized protein. (919 aa)
UMAG_04069Putative TFIIH/NER complex ATPase/helicase subunit SSL2. (940 aa)
UMAG_03777Ubiquitin carboxyl-terminal hydrolase. (918 aa)
UMAG_03434Replication factor C subunit 1. (950 aa)
UMAG_03550Chromosome 9, whole genome shotgun sequence. (329 aa)
UMAG_03141Chromosome 8, whole genome shotgun sequence. (828 aa)
UMAG_11009DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1315 aa)
UMAG_02874Chromosome 7, whole genome shotgun sequence. (1291 aa)
UMAG_06506Chromosome 7, whole genome shotgun sequence. (983 aa)
UMAG_02371Protein kinase domain-containing protein. (725 aa)
UMAG_05117Telo_bind domain-containing protein. (1050 aa)
UMAG_05151CYCLIN domain-containing protein; Belongs to the cyclin family. (493 aa)
UMAG_05156Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (623 aa)
UMAG_11783DUF1767 domain-containing protein. (451 aa)
UMAG_06296RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (491 aa)
UMAG_11392Uncharacterized protein. (156 aa)
UMAG_00848PCI domain-containing protein. (572 aa)
UMAG_00989Uncharacterized protein. (687 aa)
UMAG_01394Uncharacterized protein. (117 aa)
UMAG_00669Chromosome 1, whole genome shotgun sequence. (401 aa)
UMAG_00817Chromosome 1, whole genome shotgun sequence. (482 aa)
UMAG_06213Uncharacterized protein. (1143 aa)
UMAG_05939CMP/dCMP-type deaminase domain-containing protein. (224 aa)
UMAG_06219Uncharacterized protein. (334 aa)
UMAG_06000Chromosome 21, whole genome shotgun sequence. (1376 aa)
UMAG_11580Retrotransposon HobS hobase. (1083 aa)
UMAG_05846DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1127 aa)
UMAG_05563CULLIN_2 domain-containing protein; Belongs to the cullin family. (822 aa)
UMAG_11798Uncharacterized protein. (493 aa)
UMAG_12032Uncharacterized protein. (560 aa)
UMAG_10551General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (516 aa)
UMAG_10936Chromosome 16, whole genome shotgun sequence. (71 aa)
UMAG_05569DNA_binding_1 domain-containing protein. (170 aa)
UMAG_05574Uncharacterized protein. (722 aa)
UMAG_04902Chromosome 15, whole genome shotgun sequence; Belongs to the protein kinase superfamily. (379 aa)
UMAG_04722RPOL4c domain-containing protein. (175 aa)
UMAG_04367Reverse transcriptase domain-containing protein. (452 aa)
UMAG_11157Chromosome 15, whole genome shotgun sequence. (347 aa)
UMAG_04623Putative replication factor C subunit 3. (341 aa)
UMAG_11545YL1_C domain-containing protein. (199 aa)
UMAG_10429DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1241 aa)
UMAG_04391FHA domain-containing protein. (890 aa)
UMAG_05845WD_REPEATS_REGION domain-containing protein. (1415 aa)
UMAG_03898Uncharacterized protein. (1532 aa)
UMAG_05888Uncharacterized protein. (315 aa)
UMAG_04630ERCC4 domain-containing protein. (605 aa)
UMAG_05403Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (289 aa)
UMAG_04165Chromosome 12, whole genome shotgun sequence. (114 aa)
UMAG_04202Chromosome 12, whole genome shotgun sequence; Belongs to the peptidase C19 family. (1427 aa)
UMAG_10352Uncharacterized protein. (333 aa)
UMAG_10359DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (133 aa)
UMAG_11521Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (619 aa)
UMAG_03565Chromosome 9, whole genome shotgun sequence. (861 aa)
UMAG_12288Integrase catalytic domain-containing protein. (999 aa)
UMAG_10396Chromosome 8, whole genome shotgun sequence. (993 aa)
UMAG_03766Chromosome 10, whole genome shotgun sequence. (559 aa)
UMAG_10845UDG domain-containing protein. (511 aa)
UMAG_04344XPGN domain-containing protein. (699 aa)
UMAG_04442Putative asparagine--tRNA ligase DED81. (583 aa)
UMAG_15013PCI domain-containing protein. (518 aa)
UMAG_04588Putative ubiquitin-ribosomal 40S subunit protein S31 fusion protein. (159 aa)
UMAG_10982Chromosome 8, whole genome shotgun sequence. (139 aa)
UMAG_11946Chromosome 7, whole genome shotgun sequence. (503 aa)
UMAG_04129Chromosome 12, whole genome shotgun sequence. (983 aa)
UMAG_10658Chromosome 8, whole genome shotgun sequence. (986 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (562 aa)
UMAG_02817Chromosome 7, whole genome shotgun sequence. (243 aa)
UMAG_11475Chromosome 7, whole genome shotgun sequence. (393 aa)
UMAG_10433Chromosome 12, whole genome shotgun sequence. (138 aa)
UMAG_02863Chromosome 7, whole genome shotgun sequence. (864 aa)
UMAG_02911Chromosome 7, whole genome shotgun sequence; Belongs to the peptidase C19 family. (1453 aa)
UMAG_10322Chromosome 7, whole genome shotgun sequence. (2137 aa)
UMAG_10604CPSF_A domain-containing protein. (1511 aa)
UMAG_03001Chromosome 7, whole genome shotgun sequence. (887 aa)
UMAG_03025Chromosome 7, whole genome shotgun sequence; Component of the post-replicative DNA mismatch repair system (MMR). (963 aa)
UMAG_10486Chromosome 10, whole genome shotgun sequence. (87 aa)
UMAG_03689Chromosome 10, whole genome shotgun sequence. (260 aa)
UMAG_10286Putative nuclear transport factor. (120 aa)
UMAG_02639Putative ubiquitin-specific processing protease 21; Belongs to the peptidase C19 family. (1115 aa)
UMAG_15061Zds_C domain-containing protein. (1251 aa)
UMAG_11928Cyclin N-terminal domain-containing protein. (406 aa)
UMAG_10512Chromosome 10, whole genome shotgun sequence. (208 aa)
UMAG_11724XPA_C domain-containing protein. (356 aa)
UMAG_03394Chromosome 9, whole genome shotgun sequence. (958 aa)
UMAG_03491Chromosome 9, whole genome shotgun sequence. (306 aa)
UMAG_02324RNA_pol_L_2 domain-containing protein. (145 aa)
UMAG_05118zf-4CXXC_R1 domain-containing protein. (1020 aa)
UMAG_05201ERCC4 domain-containing protein. (846 aa)
UMAG_03200Chromosome 8, whole genome shotgun sequence. (1075 aa)
UMAG_10830Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (955 aa)
UMAG_05085Uncharacterized protein. (500 aa)
UMAG_05141UmuC domain-containing protein. (682 aa)
UMAG_10198Serine/threonine-protein phosphatase. (320 aa)
UMAG_05208DNA_mis_repair domain-containing protein. (831 aa)
UMAG_03095Chromosome 7, whole genome shotgun sequence. (781 aa)
UMAG_01931DNA polymerase. (1678 aa)
UMAG_02579Uncharacterized protein. (285 aa)
UMAG_02607Putative chromatin remodeling complex ATPase subunit. (1108 aa)
UMAG_008693'-5' exonuclease domain-containing protein. (646 aa)
UMAG_01729WD_REPEATS_REGION domain-containing protein. (805 aa)
UMAG_00907Uncharacterized protein. (487 aa)
UMAG_00922Uncharacterized protein. (422 aa)
UNG1Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (444 aa)
UMAG_11911Putative ubiquitin. (457 aa)
UMAG_11304Uncharacterized protein. (547 aa)
UMAG_02211Uncharacterized protein. (492 aa)
UMAG_02220Uncharacterized protein. (1488 aa)
UMAG_01293UmuC domain-containing protein. (763 aa)
UMAG_01085Putative DNA repair protein. (1309 aa)
UMAG_10194Putative DNA-directed RNA polymerase core subunit RPB10. (71 aa)
UMAG_05197Uncharacterized protein. (436 aa)
UMAG_06265Reverse transcriptase domain-containing protein. (1276 aa)
UMAG_10774Uncharacterized protein. (248 aa)
UMAG_01304ENDO3c domain-containing protein. (569 aa)
UMAG_00216Chromosome 1, whole genome shotgun sequence. (384 aa)
UMAG_00282Chromosome 1, whole genome shotgun sequence. (1962 aa)
UMAG_01421Uncharacterized protein. (500 aa)
UMAG_00077Chromosome 1, whole genome shotgun sequence. (522 aa)
UMAG_01742HORMA domain-containing protein. (434 aa)
UMAG_10027Chromosome 1, whole genome shotgun sequence. (535 aa)
UMAG_01790Uncharacterized protein. (804 aa)
UMAG_10261CHY-type domain-containing protein. (189 aa)
UMAG_11420Chromosome 1, whole genome shotgun sequence. (164 aa)
UMAG_10922Chromosome 1, whole genome shotgun sequence. (1296 aa)
UMAG_01932Uncharacterized protein. (971 aa)
UMAG_00447Chromosome 1, whole genome shotgun sequence. (603 aa)
UMAG_01185TFIIS central domain-containing protein. (177 aa)
UMAG_00599DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (616 aa)
UMAG_10923Chromosome 1, whole genome shotgun sequence. (1090 aa)
UMAG_10924DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (744 aa)
UMAG_00729Chromosome 1, whole genome shotgun sequence. (343 aa)
UMAG_00101Chromosome 1, whole genome shotgun sequence. (865 aa)
UMAG_00376Chromosome 1, whole genome shotgun sequence; Belongs to the peptidase C19 family. (1066 aa)
UMAG_00527Chromosome 1, whole genome shotgun sequence. (170 aa)
CHK1Serine/threonine-protein kinase CHK1; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles (By similarity). (662 aa)
UMAG_05207CBFD_NFYB_HMF domain-containing protein. (250 aa)
CPR6Peptidyl-prolyl cis-trans isomerase D; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (398 aa)
RVB1RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (488 aa)
ESA1Histone acetyltransferase ESA1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double-strand break repair through homologous recombination. Involved in cell cycle progression. Recruitment to promoters depends on [...] (565 aa)
MSH3DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] (1154 aa)
SYF1Pre-mRNA-splicing factor SYF1; Involved in pre-mRNA splicing and cell cycle progression. (1081 aa)
RRI1COP9 signalosome complex subunit 5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes; Belongs to the peptidase M67A family. CSN5 subfamily. (406 aa)
TFB5General transcription and DNA repair factor IIH subunit TFB5; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has be [...] (65 aa)
TOF1Topoisomerase 1-associated factor 1; Involved in chromosome segregation during meiosis and DNA damage repair; Belongs to the timeless family. (1251 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (658 aa)
HTB1Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (142 aa)
ISY1Pre-mRNA-splicing factor ISY1; Involved in pre-mRNA splicing. (351 aa)
UBC2Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
INO80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1910 aa)
UMAG_00675DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (637 aa)
Your Current Organism:
Ustilago maydis
NCBI taxonomy Id: 237631
Other names: U. maydis 521, Ustilago maydis 521
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