STRINGSTRING
D9C73_010056 D9C73_010056 D9C73_009673 D9C73_009673 RNF8 RNF8 D9C73_011789 D9C73_011789 D9C73_013236 D9C73_013236 D9C73_013245 D9C73_013245 D9C73_012377 D9C73_012377 D9C73_012656 D9C73_012656 D9C73_019725 D9C73_019725 D9C73_019638 D9C73_019638 D9C73_019482 D9C73_019482 D9C73_020802 D9C73_020802 D9C73_020787 D9C73_020787 D9C73_021757 D9C73_021757 D9C73_022048 D9C73_022048 D9C73_021449 D9C73_021449 D9C73_022706 D9C73_022706 D9C73_022505 D9C73_022505 D9C73_027351 D9C73_027351 D9C73_026966 D9C73_026966 D9C73_001154 D9C73_001154 D9C73_000629 D9C73_000629 RNF8-2 RNF8-2 D9C73_013788 D9C73_013788 D9C73_005541 D9C73_005541 D9C73_005553 D9C73_005553 D9C73_003550 D9C73_003550 D9C73_003606 D9C73_003606 D9C73_003625 D9C73_003625 D9C73_002814 D9C73_002814 D9C73_003094 D9C73_003094 D9C73_003183 D9C73_003183 D9C73_003150 D9C73_003150 D9C73_003067 D9C73_003067 D9C73_002860 D9C73_002860 D9C73_002839 D9C73_002839 D9C73_000838 D9C73_000838 D9C73_001143 D9C73_001143 D9C73_000598 D9C73_000598 D9C73_028487 D9C73_028487 D9C73_000703 D9C73_000703 D9C73_004890 D9C73_004890 D9C73_004798 D9C73_004798 D9C73_004793 D9C73_004793 D9C73_012285 D9C73_012285 D9C73_005333 D9C73_005333 D9C73_005041 D9C73_005041 D9C73_004861 D9C73_004861 D9C73_018150 D9C73_018150 D9C73_018761 D9C73_018761 D9C73_017148 D9C73_017148 D9C73_015125 D9C73_015125 D9C73_014576 D9C73_014576 D9C73_015472 D9C73_015472 D9C73_028401 D9C73_028401
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D9C73_010056E3 UFM1-protein ligase 1. (796 aa)
D9C73_009673Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (524 aa)
D9C73_011789Deoxynucleoside triphosphate triphosphohydrolase SAMHD1. (625 aa)
D9C73_013236SMC5-SMC6 complex localization factor protein 2. (428 aa)
D9C73_013245SMC5-SMC6 complex localization factor protein 2. (428 aa)
D9C73_012377Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (806 aa)
D9C73_012656annotation not available (1021 aa)
D9C73_019725SMC5-SMC6 complex localization factor protein 2. (839 aa)
D9C73_019638DNA polymerase eta. (733 aa)
D9C73_019482Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
D9C73_020802Tonsoku-like protein NF-kappa-B inhibitor-like protein 2. (1458 aa)
D9C73_020787Tonsoku-like protein NF-kappa-B inhibitor-like protein 2. (316 aa)
D9C73_021757SMC hinge domain-containing protein 1. (2939 aa)
D9C73_022048DNA endonuclease RBBP8. (520 aa)
D9C73_021449Checkpoint protein; Belongs to the HUS1 family. (168 aa)
D9C73_022706Cyclic GMP-AMP synthase. (165 aa)
D9C73_022505Replication protein A 14 kDa subunit. (122 aa)
D9C73_027351WD repeat-containing protein 79. (550 aa)
D9C73_026966Actin-related protein 2; Belongs to the actin family. (396 aa)
D9C73_001154Actin-related protein 3; Belongs to the actin family. (418 aa)
D9C73_000629Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (349 aa)
RNF8-2E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (524 aa)
D9C73_013788NAD-dependent protein deacetylase sirtuin-6. (351 aa)
D9C73_005541Actin-related protein 2/3 complex subunit 4. (206 aa)
D9C73_005553Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (167 aa)
D9C73_003550TP53-binding protein 1. (1744 aa)
D9C73_003606DNA damage-binding protein 1 DDB p127 subunit. (1164 aa)
D9C73_003625DNA damage-binding protein 1 DDB p127 subunit. (292 aa)
D9C73_002814Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
D9C73_003094Transitional endoplasmic reticulum ATPase. (808 aa)
D9C73_003183DNA polymerase lambda; Belongs to the DNA polymerase type-X family. (572 aa)
D9C73_003150NAD-dependent protein deacetylase sirtuin-7. (406 aa)
D9C73_003067Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (590 aa)
D9C73_002860Aprataxin and PNK-like factor. (515 aa)
D9C73_002839Aprataxin and PNK-like factor. (514 aa)
D9C73_000838Telomere-associated protein RIF1. (2467 aa)
D9C73_001143Actin-related protein 3; Belongs to the actin family. (368 aa)
D9C73_000598Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (299 aa)
D9C73_028487E3 ubiquitin-protein ligase rnf168. (492 aa)
D9C73_000703Actin-related protein 3; Belongs to the actin family. (451 aa)
D9C73_004890Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
D9C73_004798Poly [ADP-ribose] polymerase. (527 aa)
D9C73_004793E3 ubiquitin-protein ligase RAD18. (538 aa)
D9C73_012285SMC5-SMC6 complex localization factor protein 1. (856 aa)
D9C73_005333Histone-lysine N-methyltransferase SETMAR. (320 aa)
D9C73_005041Protein timeless-like protein. (1144 aa)
D9C73_004861E3 ubiquitin-protein ligase RAD18. (501 aa)
D9C73_018150Uncharacterized protein. (190 aa)
D9C73_018761WD repeat-containing protein 70. (540 aa)
D9C73_017148DNA repair protein RAD50. (1312 aa)
D9C73_015125Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (697 aa)
D9C73_014576E3 ubiquitin-protein ligase RNF169. (591 aa)
D9C73_015472Bifunctional polynucleotide phosphatase/kinase DNA 5'-kinase/3'-phosphatase. (543 aa)
D9C73_028401Protein FAM35A. (919 aa)
Your Current Organism:
Collichthys lucidus
NCBI taxonomy Id: 240159
Other names: C. lucidus, Sciaena lucida, big head croaker
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