(37 nodes) Secondary alcohol metabolic process network (Coprinopsis cinerea)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	CC1G_03978	Squalene synthase. (514 aa)
	CC1G_03987	Squalene epoxidase. (538 aa)
	CC1G_00827	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (473 aa)
	CC1G_00886	O-acyltransferase. (609 aa)
	CC1G_00893	Uncharacterized protein. (481 aa)
	CC1G_08364	Lanosterol 14-alpha-demethylase; Belongs to the cytochrome P450 family. (528 aa)
	CC1G_00372	Isocitrate dehydrogenase. (370 aa)
	CC1G_11465	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (418 aa)
	CC1G_05622	Sterol 24-C-methyltransferase. (263 aa)
	CC1G_04738	C-4 methyl sterol oxidase; Belongs to the sterol desaturase family. (330 aa)
	CC1G_05509	C-14 sterol reductase. (498 aa)
	CC1G_09662	Uncharacterized protein. (478 aa)
	CC1G_09664	Uncharacterized protein. (478 aa)
	CC1G_06149	Sterol 24-C-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (349 aa)
	CC1G_05257	Acyl-CoA synthetase. (611 aa)
	CC1G_10429	Uncharacterized protein. (473 aa)
	CC1G_03119	Squalene monooxygenase. (485 aa)
	CC1G_09961	C-8 sterol isomerase. (242 aa)
	CC1G_09970	3-keto sterol reductase. (426 aa)
	CC1G_14174	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (494 aa)
	CC1G_14616	Acetyl-CoA acetyltransferase. (689 aa)
	CC1G_15012	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (748 aa)
	CC1G_10937	C-14 sterol reductase. (443 aa)
	CC1G_03447	C-3 sterol dehydrogenase. (455 aa)
	CC1G_07728	Delta-sterol C-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (349 aa)
	CC1G_12572	Fatty acid hydroxylase; Belongs to the sterol desaturase family. (333 aa)
	CC1G_06386	Uncharacterized protein. (138 aa)
	CC1G_02886	Abhydrolase_3 domain-containing protein. (372 aa)
	CC1G_01671	C-22 sterol desaturase; Belongs to the cytochrome P450 family. (512 aa)
	CC1G_00729	Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (278 aa)
	CC1G_00576	Cytochrome-b5 reductase. (324 aa)
	CC1G_04482	Hormone-sensitive lipase. (871 aa)
	CC1G_07605	Lanosterol 14-alpha-demethylase; Belongs to the cytochrome P450 family. (558 aa)
	CC1G_00037	NADH-cytochrome b5 reductase. (319 aa)
	CC1G_00082	Uncharacterized protein. (360 aa)
	CC1G_00195	Uncharacterized protein. (632 aa)
	CC1G_00350	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (397 aa)

Your Current Organism:

Coprinopsis cinerea

NCBI taxonomy Id: 240176
Other names: C. cinerea okayama7#130, Coprinopsis cinerea okayama7#130, Coprinus cinereus okayama7#130

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CC1G_00037	CC1G_00576	A8NWI5	A8N3W4	NADH-cytochrome b5 reductase.	Cytochrome-b5 reductase.	0.900
CC1G_00350	CC1G_00372	A8NXM8	A8NXQ5	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Isocitrate dehydrogenase.	0.999
CC1G_00350	CC1G_11465	A8NXM8	A8P046	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.977
CC1G_00372	CC1G_00350	A8NXQ5	A8NXM8	Isocitrate dehydrogenase.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.999
CC1G_00372	CC1G_11465	A8NXQ5	A8P046	Isocitrate dehydrogenase.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.987
CC1G_00576	CC1G_00037	A8N3W4	A8NWI5	Cytochrome-b5 reductase.	NADH-cytochrome b5 reductase.	0.900
CC1G_00576	CC1G_15012	A8N3W4	D6RP64	Cytochrome-b5 reductase.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.466
CC1G_00729	CC1G_00827	A8N3H3	A8N8V2	Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.548
CC1G_00729	CC1G_05257	A8N3H3	A8PCD7	Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acyl-CoA synthetase.	0.545
CC1G_00729	CC1G_14616	A8N3H3	D6RMQ8	Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetyl-CoA acetyltransferase.	0.831
CC1G_00827	CC1G_00729	A8N8V2	A8N3H3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.548
CC1G_00827	CC1G_00893	A8N8V2	A8N918	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.531
CC1G_00827	CC1G_01671	A8N8V2	A8N2H1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	C-22 sterol desaturase; Belongs to the cytochrome P450 family.	0.738
CC1G_00827	CC1G_03119	A8N8V2	A8PF05	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Squalene monooxygenase.	0.811
CC1G_00827	CC1G_03447	A8N8V2	A8NQS0	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	C-3 sterol dehydrogenase.	0.728
CC1G_00827	CC1G_03978	A8N8V2	A8N8D1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Squalene synthase.	0.924
CC1G_00827	CC1G_03987	A8N8V2	A8N8E0	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Squalene epoxidase.	0.811
CC1G_00827	CC1G_04738	A8N8V2	A8P2D6	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	C-4 methyl sterol oxidase; Belongs to the sterol desaturase family.	0.926
CC1G_00827	CC1G_05257	A8N8V2	A8PCD7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acyl-CoA synthetase.	0.435
CC1G_00827	CC1G_05509	A8N8V2	A8P5J2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	C-14 sterol reductase.	0.639