STRINGSTRING
Ava_1603 Ava_1603 Ava_1405 Ava_1405 Ava_1292 Ava_1292 Ava_1106 Ava_1106 rpoC1 rpoC1 rpoB rpoB selO selO Ava_3872 Ava_3872 Ava_3833 Ava_3833 dnaG dnaG Ava_3469 Ava_3469 cugP cugP rpoC2 rpoC2 Ava_4414 Ava_4414 Ava_4814 Ava_4814 Ava_4927 Ava_4927 Ava_3356 Ava_3356 Ava_3329 Ava_3329 pnp pnp Ava_3234 Ava_3234 Ava_2939 Ava_2939 Ava_2938 Ava_2938 Ava_2937 Ava_2937 Ava_2936 Ava_2936 Ava_2680 Ava_2680 rph rph ispD ispD Ava_0002 Ava_0002 Ava_0182 Ava_0182 nadD nadD mobA mobA polA polA rpoA rpoA dacA dacA sat sat nadD-2 nadD-2 dnaX dnaX Ava_2118 Ava_2118 glgC glgC rpoZ rpoZ coaD coaD Ava_1963 Ava_1963 Ava_1818 Ava_1818 glmU glmU Ava_1708 Ava_1708 Ava_1625 Ava_1625
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ava_1603Intein. (877 aa)
Ava_1405Mannose-6-phosphate isomerase, type 2. (135 aa)
Ava_1292Mannose-6-phosphate isomerase, type 2. (140 aa)
Ava_1106Nucleotidyl transferase. (257 aa)
rpoC1DNA-directed RNA polymerase gamma chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (625 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1117 aa)
selOProtein of unknown function UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). (485 aa)
Ava_3872Adenosylcobinamide kinase. (184 aa)
Ava_3833Polynucleotide adenylyltransferase region. (422 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (640 aa)
Ava_3469DNA polymerase III, delta subunit. (329 aa)
cugPNucleotidyl transferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. (389 aa)
rpoC2DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily. (1355 aa)
Ava_4414Conserved hypothetical protein. (100 aa)
Ava_4814Hypothetical protein. (534 aa)
Ava_4927UDP-glucose pyrophosphorylase. (293 aa)
Ava_3356Glucose-1-phosphate thymidylyltransferase, short form. (358 aa)
Ava_3329Ap4A phosphorylase II. (314 aa)
pnp3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (718 aa)
Ava_3234Putative diguanylate cyclase (GGDEF domain). (295 aa)
Ava_2939Phycobilisome linker polypeptide; Belongs to the phycobilisome linker protein family. (253 aa)
Ava_2938Phycobilisome linker polypeptide; Belongs to the phycobilisome linker protein family. (237 aa)
Ava_2937Phycobilisome linker polypeptide; Belongs to the phycobilisome linker protein family. (247 aa)
Ava_2936Phycobilisome linker polypeptide; Belongs to the phycobilisome linker protein family. (279 aa)
Ava_2680Mannose-1-phosphate guanylyltransferase (GDP). (354 aa)
rphRNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (247 aa)
ispD4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (228 aa)
Ava_0002DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (387 aa)
Ava_0182Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domains I and III. (842 aa)
nadDProbable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa)
mobAMolybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (207 aa)
polADNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (977 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (315 aa)
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (321 aa)
satSulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (392 aa)
nadD-2Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (208 aa)
dnaXAAA ATPase, central region; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (650 aa)
Ava_2118FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. (352 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (429 aa)
rpoZRNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (78 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (212 aa)
Ava_1963DNA polymerase III, delta prime subunit. (320 aa)
Ava_1818Phosphatidate cytidylyltransferase; Belongs to the CDS family. (332 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa)
Ava_1708Phosphoesterase, RecJ-like protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (904 aa)
Ava_1625Conserved hypothetical protein. (466 aa)
Your Current Organism:
Trichormus variabilis
NCBI taxonomy Id: 240292
Other names: Anabaena flos-aquae A-37, Anabaena flos-aquae UTCC 67, Anabaena sp. CCALA 007, Anabaena sp. PCC 7937, Anabaena variabilis ATCC 29413, Anabaena variabilis IAM M-204, Anabaena variabilis NIES-2095, Anabaena variabilis UTCC 105, Nostoc sp. PCC 7937, T. variabilis ATCC 29413, Trichormus variabilis ATCC 29413
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