STRINGSTRING
Ava_0139 Ava_0139 accD accD gloB gloB Ava_0441 Ava_0441 ackA ackA Ava_0494 Ava_0494 Ava_0516 Ava_0516 Ava_0938 Ava_0938 Ava_1080 Ava_1080 acsA acsA mdh mdh Ava_1491 Ava_1491 Ava_1694 Ava_1694 Ava_1927 Ava_1927 leuA leuA ppc ppc Ava_2314 Ava_2314 Ava_2458 Ava_2458 accA accA Ava_2660 Ava_2660 nifJ nifJ Ava_3176 Ava_3176 Ava_3216 Ava_3216 Ava_3388 Ava_3388 Ava_3556 Ava_3556 Ava_3615 Ava_3615 Ava_3841 Ava_3841 Ava_3956 Ava_3956 Ava_4041 Ava_4041 pdhA pdhA acyP acyP Ava_4569 Ava_4569
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ava_0139Glyoxalase I. (145 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (316 aa)
gloBBeta-lactamase-like protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (257 aa)
Ava_0441PEP-utilizing enzyme, mobile region. (963 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
Ava_0494Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa)
Ava_0516acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
Ava_0938Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (378 aa)
Ava_1080Ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. (1190 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (657 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (324 aa)
Ava_1491Transketolase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
Ava_1694Pyruvate kinase; Belongs to the pyruvate kinase family. (589 aa)
Ava_1927Dihydrolipoamide dehydrogenase. (475 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (531 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (1023 aa)
Ava_2314Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (182 aa)
Ava_2458Amino acid-binding ACT. (463 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa)
Ava_2660D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region. (341 aa)
nifJFerredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase. (1190 aa)
Ava_3176Biotin/lipoyl attachment. (432 aa)
Ava_32162-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (577 aa)
Ava_3388Phosphoenolpyruvate synthase. (775 aa)
Ava_3556Fumarase. (471 aa)
Ava_3615Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (460 aa)
Ava_3841Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (819 aa)
Ava_3956Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (377 aa)
Ava_4041Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (372 aa)
pdhADehydrogenase, E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa)
acyPAcylphosphatase. (101 aa)
Ava_4569Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (821 aa)
Your Current Organism:
Trichormus variabilis
NCBI taxonomy Id: 240292
Other names: Anabaena flos-aquae A-37, Anabaena flos-aquae UTCC 67, Anabaena sp. CCALA 007, Anabaena sp. PCC 7937, Anabaena variabilis ATCC 29413, Anabaena variabilis IAM M-204, Anabaena variabilis NIES-2095, Anabaena variabilis UTCC 105, Nostoc sp. PCC 7937, T. variabilis ATCC 29413, Trichormus variabilis ATCC 29413
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