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ilvD ilvD ilvC ilvC coaE coaE panC/cmk panC/cmk coaX coaX coaD coaD Ava_2035 Ava_2035 Ava_2597 Ava_2597 Ava_2757 Ava_2757 Ava_2981 Ava_2981 Ava_3533 Ava_3533 panD panD Ava_3615 Ava_3615 Ava_3811 Ava_3811 panB panB
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene fusions
gene co-occurrence
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ilvDDihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (563 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (196 aa)
panC/cmkCytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (534 aa)
coaXPutative transcriptional acitvator, Baf; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (295 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (212 aa)
Ava_2035Acetolactate synthase, small subunit. (182 aa)
Ava_25974'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (237 aa)
Ava_2757Acetolactate synthase, large subunit. (632 aa)
Ava_2981Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (319 aa)
Ava_3533Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. (547 aa)
panDL-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa)
Ava_3615Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (460 aa)
Ava_3811Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (410 aa)
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (257 aa)
Your Current Organism:
Trichormus variabilis
NCBI taxonomy Id: 240292
Other names: Anabaena flos-aquae A-37, Anabaena flos-aquae UTCC 67, Anabaena sp. CCALA 007, Anabaena sp. PCC 7937, Anabaena variabilis ATCC 29413, Anabaena variabilis IAM M-204, Anabaena variabilis NIES-2095, Anabaena variabilis UTCC 105, Nostoc sp. PCC 7937, T. variabilis ATCC 29413, Trichormus variabilis ATCC 29413
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