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polA_1 polA_1 CDQ17969.1 CDQ17969.1 uvrC uvrC polA_2 polA_2 ypcP ypcP CDQ18665.1 CDQ18665.1 CDQ18684.1 CDQ18684.1 uvrB uvrB uvrA uvrA CDQ19422.1 CDQ19422.1 lexA lexA helD_1 helD_1 pcrA_1 pcrA_1 pcrA_2 pcrA_2 yjcD yjcD ligA ligA pcrA_3 pcrA_3 addA addA helD_2 helD_2 CDQ21684.1 CDQ21684.1 polA_3 polA_3 mfd_2 mfd_2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
polA_1DNA polymerase I, thermostable. (648 aa)
CDQ17969.1PD-(D/E)XK nuclease superfamily protein. (391 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (598 aa)
polA_2DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (879 aa)
ypcP5'-3' exonuclease. (291 aa)
CDQ18665.1PD-(D/E)XK nuclease superfamily protein. (312 aa)
CDQ18684.1ATP-dependent DNA helicase DinG. (759 aa)
uvrBExcinuclease ABC subunit B. (659 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (958 aa)
CDQ19422.1Hypothetical protein. (385 aa)
lexALexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (207 aa)
helD_1Helicase IV. (769 aa)
pcrA_1ATP-dependent DNA helicase PcrA. (192 aa)
pcrA_2ATP-dependent DNA helicase PcrA. (517 aa)
yjcDPutative ATP-dependent DNA helicase YjcD. (732 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (668 aa)
pcrA_3ATP-dependent DNA helicase PcrA. (747 aa)
addAATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase. (1239 aa)
helD_2Helicase IV. (753 aa)
CDQ21684.1Excinuclease ABC subunit C. (250 aa)
polA_3DNA polymerase I, thermostable. (816 aa)
mfd_2Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1178 aa)
Your Current Organism:
Halobacillus dabanensis
NCBI taxonomy Id: 240302
Other names: CGMCC 1.3704, H. dabanensis, Halobacillus dabanensis Liu et al. 2005, Halobacillus sp. D-8, JCM 12772, strain D-8
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