STRINGSTRING
PRP28 PRP28 PRP5 PRP5 LSM6 LSM6 MGG_06666 MGG_06666 MGG_05375 MGG_05375 MGG_06705 MGG_06705 MGG_05636 MGG_05636 MGG_13154 MGG_13154 MGG_11091 MGG_11091 MGG_04727 MGG_04727 MGG_04693 MGG_04693 LSM5 LSM5 MGG_01450 MGG_01450 MGG_07085 MGG_07085 LSM8 LSM8 LSM4 LSM4 MGG_07115 MGG_07115 MGG_15082 MGG_15082 MGG_04741 MGG_04741 MGG_01579 MGG_01579 MGG_07213 MGG_07213 MGG_15607 MGG_15607 MGG_08329 MGG_08329 MGG_07998 MGG_07998 MGG_10740 MGG_10740 MGG_11257 MGG_11257 MGG_01259 MGG_01259 MGG_14070 MGG_14070 MGG_04351 MGG_04351 MGG_12316 MGG_12316 MGG_08209 MGG_08209 MGG_15536 MGG_15536 MGG_05805 MGG_05805 MGG_16920 MGG_16920 MGG_12972 MGG_12972 LSM3 LSM3 MGG_05878 MGG_05878 MGG_05173 MGG_05173 MGG_06022 MGG_06022 MGG_05244 MGG_05244 MGG_03658 MGG_03658 MGG_03636 MGG_03636 MGG_13500 MGG_13500 LSM1 LSM1 MGG_03182 MGG_03182 MGG_01157 MGG_01157 MGG_01095 MGG_01095 MGG_00356 MGG_00356 MGG_00355 MGG_00355 MGG_00716 MGG_00716 MGG_04083 MGG_04083 MGG_04013 MGG_04013 MGG_03973 MGG_03973 MGG_03895 MGG_03895 MGG_12016 MGG_12016 MGG_02655 MGG_02655 MGG_02946 MGG_02946 MGG_02938 MGG_02938 RSE1 RSE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRP28Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity). (674 aa)
PRP5Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. (1012 aa)
LSM6U6 snRNA-associated Sm-like protein LSm6; Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2- LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 [...] (83 aa)
MGG_06666Uncharacterized protein. (239 aa)
MGG_05375Splicing factor 3a subunit 2. (247 aa)
MGG_06705Uncharacterized protein. (160 aa)
MGG_05636Uncharacterized protein. (338 aa)
MGG_13154Pre-mRNA-processing factor 31. (596 aa)
MGG_11091Cutinase; Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. (233 aa)
MGG_04727U4/U6 snRNA-associated-splicing factor PRP24. (1133 aa)
MGG_04693WD repeat-containing protein 57. (352 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (82 aa)
MGG_01450Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (95 aa)
MGG_07085Small nuclear ribonucleoprotein U1a. (234 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (101 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (121 aa)
MGG_07115Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (143 aa)
MGG_15082Uncharacterized protein. (358 aa)
MGG_04741Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (125 aa)
MGG_01579Pre-mRNA branch site protein p14. (115 aa)
MGG_07213Pre-mRNA-splicing factor prp1. (924 aa)
MGG_15607RRM domain-containing protein. (405 aa)
MGG_08329DNA replication protein 4. (567 aa)
MGG_07998U1 zinc finger domain-containing protein. (291 aa)
MGG_10740Small nuclear ribonucleoprotein G. (88 aa)
MGG_11257Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (182 aa)
MGG_01259Pre-mRNA splicing factor. (531 aa)
MGG_14070C2H2-type domain-containing protein. (236 aa)
MGG_04351U2 small nuclear ribonucleoprotein B. (207 aa)
MGG_12316Uncharacterized protein. (297 aa)
MGG_08209U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (218 aa)
MGG_15536Uncharacterized protein. (2216 aa)
MGG_05805Uncharacterized protein. (245 aa)
MGG_16920Sm domain-containing protein. (205 aa)
MGG_12972Splicing factor 3a subunit 3. (521 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
MGG_05878Extracellular metalloprotease. (618 aa)
MGG_05173Uncharacterized protein. (110 aa)
MGG_06022Uncharacterized protein. (1435 aa)
MGG_05244Pre-mRNA-processing-splicing factor 8. (2373 aa)
MGG_03658Splicing factor subunit; Belongs to the SF3B5 family. (93 aa)
MGG_03636Pre-mRNA-splicing factor 38A. (272 aa)
MGG_13500U5 small nuclear ribonucleoprotein component. (989 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (176 aa)
MGG_03182Splicing factor 3B subunit 2. (614 aa)
MGG_01157U4/U6 small nuclear ribonucleoprotein Prp3. (487 aa)
MGG_01095Uncharacterized protein. (644 aa)
MGG_00356Splicing factor 3B subunit 1. (1215 aa)
MGG_00355U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (97 aa)
MGG_00716Microfibril-associated protein. (489 aa)
MGG_04083Small nuclear ribonucleoprotein Sm D3. (119 aa)
MGG_04013Small nuclear ribonucleoprotein Sm D2. (117 aa)
MGG_03973Splicing factor 3B subunit 4. (407 aa)
MGG_03895Small nuclear ribonucleoprotein F. (88 aa)
MGG_12016Cutinase domain-containing protein. (236 aa)
MGG_02655Uncharacterized protein. (582 aa)
MGG_02946Pre-mRNA-splicing factor sap114. (536 aa)
MGG_02938Sm domain-containing protein. (146 aa)
RSE1Pre-mRNA-splicing factor RSE1; Involved in pre-mRNA splicing and cell cycle control. (1216 aa)
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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