STRINGSTRING
MGG_02491 MGG_02491 MGG_06985 MGG_06985 MGG_11757 MGG_11757 MGG_02461 MGG_02461 MGG_11387 MGG_11387 MGG_01470 MGG_01470 MGG_04585 MGG_04585 MGG_07124 MGG_07124 MGG_15576 MGG_15576 MGG_11342 MGG_11342 MGG_14764 MGG_14764 MGG_12276 MGG_12276 MGG_09555 MGG_09555 MGG_05040 MGG_05040 MGG_08594 MGG_08594 MGG_03268 MGG_03268 MGG_00685 MGG_00685 MGG_01032 MGG_01032 MGG_02656 MGG_02656 RHM52 RHM52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MGG_02491DNA replication ATP-dependent helicase dna2. (1689 aa)
MGG_06985RECA_2 domain-containing protein. (548 aa)
MGG_11757DNA damage response protein RcaA. (881 aa)
MGG_024613'-5' exonuclease domain-containing protein. (638 aa)
MGG_11387DNA repair protein RAD50. (1316 aa)
MGG_01470RECA_2 domain-containing protein. (387 aa)
MGG_04585Crossover junction endonuclease MUS81. (594 aa)
MGG_07124Replication protein A 32 kDa subunit. (275 aa)
MGG_15576DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (353 aa)
MGG_11342DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (669 aa)
MGG_14764Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2930 aa)
MGG_12276BRCT domain-containing protein. (1015 aa)
MGG_09555Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (731 aa)
MGG_05040Uncharacterized protein. (918 aa)
MGG_08594BRCT domain-containing protein. (1244 aa)
MGG_03268DUF1767 domain-containing protein. (265 aa)
MGG_00685Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (610 aa)
MGG_01032BRCT domain-containing protein. (840 aa)
MGG_02656Protein kinase rad3; Belongs to the PI3/PI4-kinase family. (2462 aa)
RHM52DNA repair and recombination protein rhm52; Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity). Belongs to the RAD52 family. (555 aa)
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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