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TOA2 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with tbp mediates transcriptional activity (By similarity). (116 aa) | ||||
SSN3 | Serine/threonine-protein kinase SSN3; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity). (499 aa) | ||||
RGR1 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (1108 aa) | ||||
SSN8 | RNA polymerase II holoenzyme cyclin-like subunit; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By s [...] (363 aa) | ||||
MGG_10529 | Fungal specific transcription factor domain-containing protein. (790 aa) | ||||
MGG_10544 | Git3 domain-containing protein. (490 aa) | ||||
MGG_04477 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1456 aa) | ||||
MGG_06677 | RPOL4c domain-containing protein. (158 aa) | ||||
MGG_05370 | Transcription initiation factor IIB. (371 aa) | ||||
MGG_13036 | Uncharacterized protein. (332 aa) | ||||
MGG_06690 | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (516 aa) | ||||
MED11 | Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (197 aa) | ||||
MGG_06742 | Uncharacterized protein. (784 aa) | ||||
MGG_06750 | TSPc domain-containing protein. (748 aa) | ||||
MGG_06797 | Git3 domain-containing protein. (574 aa) | ||||
MGG_11817 | C-type cyclin; Belongs to the cyclin family. (493 aa) | ||||
MGG_15176 | Cyclin-H. (397 aa) | ||||
MGG_06909 | HTH TFE/IIEalpha-type domain-containing protein. (418 aa) | ||||
MGG_06916 | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (123 aa) | ||||
MGG_06928 | CMGC/CDK protein kinase. (555 aa) | ||||
MGG_06937 | NIF domain-containing protein. (485 aa) | ||||
MGG_06943 | Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (122 aa) | ||||
MGG_05638 | Uncharacterized protein. (143 aa) | ||||
MGG_02122 | Uncharacterized protein. (575 aa) | ||||
MGG_06984 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1158 aa) | ||||
MGG_09284 | DNA-directed RNA polymerase I and III subunit RPAC1. (373 aa) | ||||
MGG_04720 | BTP domain-containing protein. (395 aa) | ||||
MGG_16287 | Uncharacterized protein. (414 aa) | ||||
MGG_04714 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1276 aa) | ||||
MGG_02463 | RNA_pol_L_2 domain-containing protein. (130 aa) | ||||
MGG_02478 | Uncharacterized protein. (575 aa) | ||||
MGG_04508 | RPOL4c domain-containing protein. (150 aa) | ||||
MGG_04490 | Uncharacterized protein. (427 aa) | ||||
MGG_07080 | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (155 aa) | ||||
MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1022 aa) | ||||
MGG_15720 | CDC73_C domain-containing protein. (421 aa) | ||||
MGG_04652 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1757 aa) | ||||
MGG_04761 | Uncharacterized protein. (394 aa) | ||||
MGG_01572 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1240 aa) | ||||
MGG_14751 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (556 aa) | ||||
MGG_01654 | Uncharacterized protein. (692 aa) | ||||
MGG_07291 | CMGC/CDK/CRK7 protein kinase. (1198 aa) | ||||
MGG_15089 | Uncharacterized protein. (93 aa) | ||||
MGG_07316 | FACT complex subunit spt-16. (1034 aa) | ||||
MGG_15601 | TATA-box-binding protein. (255 aa) | ||||
MGG_01717 | Uncharacterized protein. (686 aa) | ||||
MGG_14759 | Uncharacterized protein. (263 aa) | ||||
MGG_11142 | Uncharacterized protein. (205 aa) | ||||
MGG_01784 | Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (144 aa) | ||||
MED18 | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (290 aa) | ||||
MGG_01817 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (768 aa) | ||||
MGG_11130 | Uncharacterized protein. (712 aa) | ||||
MGG_08341 | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (249 aa) | ||||
MGG_01207 | Transcription initiation factor TFIID subunit 1. (1157 aa) | ||||
MGG_15646 | DNA-directed RNA polymerase N/8 kDa subunit. (78 aa) | ||||
MGG_01235 | Uncharacterized protein. (407 aa) | ||||
MGG_01258 | Cyclin-K; Belongs to the cyclin family. (486 aa) | ||||
MGG_12268 | Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1026 aa) | ||||
MGG_15967 | Uncharacterized protein. (216 aa) | ||||
MGG_15969 | Uncharacterized protein. (216 aa) | ||||
MGG_10446 | DNA-directed RNA polymerase III subunit RPC6. (415 aa) | ||||
MGG_01265 | BTP domain-containing protein. (222 aa) | ||||
MGG_01266 | TAFII55_N domain-containing protein. (536 aa) | ||||
MGG_01310 | Uncharacterized protein. (278 aa) | ||||
MGG_15669 | Uncharacterized protein. (656 aa) | ||||
MGG_15675 | Repressor of RNA polymerase III transcription MAF1; Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (378 aa) | ||||
MGG_10830 | DNA-directed RNA polymerase III polypeptide. (213 aa) | ||||
MGG_11061 | Uncharacterized protein. (558 aa) | ||||
MED5 | Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1063 aa) | ||||
MED10 | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (186 aa) | ||||
MGG_05321 | DNA-directed RNA polymerase I. (151 aa) | ||||
MGG_07391 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (131 aa) | ||||
MGG_07394 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (115 aa) | ||||
MGG_05807 | Uncharacterized protein. (400 aa) | ||||
MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (347 aa) | ||||
MGG_09574 | Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (208 aa) | ||||
MGG_13401 | CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (410 aa) | ||||
MGG_09459 | TAFII28 domain-containing protein. (420 aa) | ||||
MGG_04877 | Transcription initiation factor TFIID subunit 6. (512 aa) | ||||
MGG_16681 | Uncharacterized protein. (324 aa) | ||||
MGG_07679 | Uncharacterized protein. (620 aa) | ||||
MGG_05010 | Uncharacterized protein. (372 aa) | ||||
MGG_05952 | Uncharacterized protein. (511 aa) | ||||
MGG_05198 | DUF4211 domain-containing protein. (543 aa) | ||||
MGG_06083 | DNA-directed RNA polymerase I. (230 aa) | ||||
MGG_12891 | Uncharacterized protein. (436 aa) | ||||
MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (315 aa) | ||||
MGG_06509 | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (310 aa) | ||||
MGG_06499 | Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. (1523 aa) | ||||
MGG_17053 | Uncharacterized protein. (406 aa) | ||||
MGG_03637 | TATA-binding protein associated factor Taf2. (1579 aa) | ||||
MGG_06470 | DNA repair helicase RAD25. (835 aa) | ||||
MGG_06462 | Tetratricopeptide repeat protein 1. (1221 aa) | ||||
MGG_13511 | Transcription elongation factor S-II. (304 aa) | ||||
MGG_03605 | CDK-activating kinase assembly factor MAT1. (360 aa) | ||||
MGG_06381 | Uncharacterized protein. (437 aa) | ||||
MGG_06377 | CID domain-containing protein. (262 aa) | ||||
MGG_13542 | DEAD_2 domain-containing protein. (921 aa) | ||||
MGG_03485 | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (866 aa) | ||||
MGG_06311 | DNA-directed RNA polymerase I and III polypeptide. (149 aa) | ||||
MGG_06274 | Uncharacterized protein. (495 aa) | ||||
MGG_06271 | Uncharacterized protein. (219 aa) | ||||
MGG_06257 | Git3 domain-containing protein. (581 aa) | ||||
MGG_10067 | Uncharacterized protein. (295 aa) | ||||
MGG_16998 | Uncharacterized protein. (216 aa) | ||||
MGG_10674 | RPA43_OB domain-containing protein. (536 aa) | ||||
MGG_03225 | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (667 aa) | ||||
MGG_03215 | DNA-directed RNA polymerase II subunit RPB3. (330 aa) | ||||
MGG_09781 | Uncharacterized protein. (270 aa) | ||||
MGG_03192 | RNA polymerase II transcription factor B subunit 1. (653 aa) | ||||
MGG_03132 | DNA repair helicase rad15. (795 aa) | ||||
MGG_00531 | Abhydrolase_4 domain-containing protein. (534 aa) | ||||
MGG_17442 | Uncharacterized protein. (172 aa) | ||||
MGG_01158 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1719 aa) | ||||
MGG_00397 | RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (490 aa) | ||||
MGG_00958 | Plus3 domain-containing protein. (591 aa) | ||||
MED9 | Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (147 aa) | ||||
MGG_00885 | TFIID_20kDa domain-containing protein. (814 aa) | ||||
MGG_00138 | SANT domain-containing protein. (751 aa) | ||||
MGG_11491 | Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1407 aa) | ||||
MGG_00117 | Transcription initiation factor IIB. (701 aa) | ||||
MGG_11667 | Uncharacterized protein. (76 aa) | ||||
MGG_17657 | Uncharacterized protein. (137 aa) | ||||
MGG_08761 | Peptidase S41 family protein. (898 aa) | ||||
MGG_08722 | Uncharacterized protein. (258 aa) | ||||
MGG_08694 | Uncharacterized protein. (401 aa) | ||||
MGG_10876 | TSPc domain-containing protein. (773 aa) | ||||
MED6 | Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (328 aa) | ||||
MGG_03956 | Uncharacterized protein. (164 aa) | ||||
MGG_03877 | RNA polymerase II transcription factor B subunit 4. (380 aa) | ||||
MGG_10697 | DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (265 aa) | ||||
MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (677 aa) | ||||
MGG_02631 | Uncharacterized protein. (621 aa) | ||||
MGG_02925 | Uncharacterized protein. (336 aa) | ||||
MGG_02846 | Med12 domain-containing protein. (1569 aa) | ||||
MGCH7_ch7g167 | Transcription factor IWS1. (422 aa) | ||||
MGCH7_ch7g875 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (110 aa) | ||||
MGCH7_ch7g874 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (132 aa) |