58 items (Pyricularia oryzae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IRS4	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity). (680 aa)
	PAN1	Actin cytoskeleton-regulatory complex protein PAN1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1462 aa)
	MDV1	Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family. (661 aa)
	MGG_06649	EF hand domain-containing protein. (1300 aa)
	MGG_16334	Uncharacterized protein. (1095 aa)
	MGG_15413	GED domain-containing protein. (365 aa)
	MGG_05456	CFEM domain-containing protein. (194 aa)
	MGG_05484	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (437 aa)
	MGG_05531	CFEM domain-containing protein. (173 aa)
	MGG_05534	BAR domain-containing protein. (468 aa)
	MGG_02042	Interferon-induced GTP-binding protein Mx2. (693 aa)
	MGG_02049	Interferon-induced GTP-binding protein Mx2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (711 aa)
	MGG_06876	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (234 aa)
	MGG_11801	AP-1 complex subunit gamma. (845 aa)
	MGG_02064	Helo_like_N domain-containing protein. (402 aa)
	MGG_02114	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (812 aa)
	MGG_10633	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (448 aa)
	MGG_10640	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (742 aa)
	MGG_02383	Uncharacterized protein. (287 aa)
	MGG_02434	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (187 aa)
	MGG_11902	Mitochondrial dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (966 aa)
	MGG_10656	Dynamin family protein. (378 aa)
	MGG_04616	Epsin-1. (587 aa)
	MGG_11326	NAK protein kinase. (1045 aa)
	MGG_01762	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
	MGG_10803	Uncharacterized protein. (392 aa)
	MGG_01846	AP-3 complex beta3B subunit. (812 aa)
	MGG_01208	Uncharacterized protein. (212 aa)
	MGG_15796	GED domain-containing protein. (109 aa)
	MGG_10448	ENTH domain-containing protein. (554 aa)
	MGG_08098	AP-3 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family. (577 aa)
	MGG_15670	Uncharacterized protein. (289 aa)
	MGG_11227	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (155 aa)
	MGG_06216	Uncharacterized protein. (471 aa)
	MGG_09570	CFEM domain-containing protein. (321 aa)
	MGG_07768	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1680 aa)
	MGG_07481	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1033 aa)
	MGG_09517	Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (698 aa)
	MGG_07490	Uncharacterized protein. (211 aa)
	MGG_09493	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (989 aa)
	MGG_04906	muHD domain-containing protein. (774 aa)
	MGG_16725	Uncharacterized protein. (510 aa)
	MGG_06075	Mitochondrial fission 1 protein; Has a role in mitochondrial fission. (154 aa)
	MGG_06078	Adaptin ear-binding coat-associated protein 2. (277 aa)
	MGG_06526	GED domain-containing protein. (325 aa)
	MGG_13514	ENTH domain-containing protein. (615 aa)
	MGG_06361	Dynamin-A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
	MGG_03320	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (738 aa)
	MGG_17540	Uncharacterized protein. (399 aa)
	MGG_12178	Uncharacterized protein. (298 aa)
	MGG_15369	GED domain-containing protein. (304 aa)
	MGG_04289	Dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (520 aa)
	MGG_03800	GED domain-containing protein. (224 aa)
	MGG_04150	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (724 aa)
	MGG_04148	Rad60-SLD_2 domain-containing protein. (263 aa)
	MGG_02648	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (733 aa)
	MGG_02958	SMP-LTD domain-containing protein. (1015 aa)
	MGG_02949	Cytoskeleton assembly control protein Sla2. (1048 aa)

Your Current Organism:

Pyricularia oryzae

NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IRS4	MGG_01762	A4QST9	G4MVD4	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.610
IRS4	MGG_03320	A4QST9	G4N974	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.415
IRS4	MGG_04148	A4QST9	G4NIR0	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	Rad60-SLD_2 domain-containing protein.	0.415
IRS4	MGG_04150	A4QST9	G4NIQ6	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.415
IRS4	MGG_04616	A4QST9	G4MSW7	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	Epsin-1.	0.535
IRS4	MGG_05484	A4QST9	G4MM57	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.575
IRS4	MGG_06078	A4QST9	G4N575	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	Adaptin ear-binding coat-associated protein 2.	0.484
IRS4	MGG_06876	A4QST9	G4MMW9	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.580
IRS4	MGG_07481	A4QST9	G4N1A2	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	0.486
IRS4	MGG_07768	A4QST9	G4N0Z8	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.621
IRS4	MGG_10448	A4QST9	G4MY15	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	ENTH domain-containing protein.	0.535
IRS4	MGG_11326	A4QST9	G4MV67	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	NAK protein kinase.	0.412
IRS4	MGG_11801	A4QST9	G4MMY1	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	AP-1 complex subunit gamma.	0.486
IRS4	MGG_13514	A4QST9	G4N7C0	Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).	ENTH domain-containing protein.	0.515
MDV1	MGG_02114	A4RJV3	G4MNQ6	Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.569
MDV1	MGG_02648	A4RJV3	G4NJH9	Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family.	Interferon-induced GTP-binding protein Mx; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.569
MDV1	MGG_06075	A4RJV3	G4N571	Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family.	Mitochondrial fission 1 protein; Has a role in mitochondrial fission.	0.967
MDV1	MGG_06361	A4RJV3	G4N7U4	Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family.	Dynamin-A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.877
MDV1	MGG_09517	A4RJV3	G4N1E7	Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family.	Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.749
MDV1	MGG_11902	A4RJV3	G4MRW6	Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family.	Mitochondrial dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.412