node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HTZ1 | MGG_00136 | A4QVR2 | G4NE82 | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | HMG box domain-containing protein. | 0.694 |
HTZ1 | MGG_06043 | A4QVR2 | G4N4X5 | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | Histone deacetylase HOS3. | 0.552 |
HTZ1 | MGG_11491 | A4QVR2 | G4NEB7 | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. | 0.477 |
MGG_00136 | HTZ1 | G4NE82 | A4QVR2 | HMG box domain-containing protein. | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | 0.694 |
MGG_00136 | MGG_16762 | G4NE82 | G4N5J9 | HMG box domain-containing protein. | Uncharacterized protein; Belongs to the actin family. | 0.788 |
MGG_00338 | MGG_06094 | G4NCX0 | G4N594 | Uncharacterized protein. | DNA repair protein RAD5. | 0.419 |
MGG_00338 | MGG_16762 | G4NCX0 | G4N5J9 | Uncharacterized protein. | Uncharacterized protein; Belongs to the actin family. | 0.512 |
MGG_00754 | MGG_01082 | G4NEN2 | G4NCH4 | Uncharacterized protein. | PAPA-1 domain-containing protein. | 0.578 |
MGG_00754 | MGG_16762 | G4NEN2 | G4N5J9 | Uncharacterized protein. | Uncharacterized protein; Belongs to the actin family. | 0.598 |
MGG_01082 | MGG_00754 | G4NCH4 | G4NEN2 | PAPA-1 domain-containing protein. | Uncharacterized protein. | 0.578 |
MGG_01082 | MGG_16762 | G4NCH4 | G4N5J9 | PAPA-1 domain-containing protein. | Uncharacterized protein; Belongs to the actin family. | 0.532 |
MGG_06043 | HTZ1 | G4N4X5 | A4QVR2 | Histone deacetylase HOS3. | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | 0.552 |
MGG_06094 | MGG_00338 | G4N594 | G4NCX0 | DNA repair protein RAD5. | Uncharacterized protein. | 0.419 |
MGG_06094 | MGG_16762 | G4N594 | G4N5J9 | DNA repair protein RAD5. | Uncharacterized protein; Belongs to the actin family. | 0.512 |
MGG_07155 | MGG_16762 | G4MT81 | G4N5J9 | Transcription termination factor 2. | Uncharacterized protein; Belongs to the actin family. | 0.512 |
MGG_08463 | MGG_09869 | G4NA99 | G4NID8 | Transcription factor MBP1. | Uncharacterized protein. | 0.996 |
MGG_09363 | MGG_16762 | G4NI33 | G4N5J9 | Uncharacterized protein. | Uncharacterized protein; Belongs to the actin family. | 0.512 |
MGG_09869 | MGG_08463 | G4NID8 | G4NA99 | Uncharacterized protein. | Transcription factor MBP1. | 0.996 |
MGG_11047 | MGG_16762 | G4MXZ7 | G4N5J9 | DNA repair and recombination protein RAD5C. | Uncharacterized protein; Belongs to the actin family. | 0.512 |
MGG_11491 | HTZ1 | G4NEB7 | A4QVR2 | Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] | 0.477 |