STRINGSTRING
ATG18 ATG18 MGG_01031 MGG_01031 MGG_04174 MGG_04174 MGG_04054 MGG_04054 MGG_04050 MGG_04050 MGG_03971 MGG_03971 MGG_03919 MGG_03919 MGG_09383 MGG_09383 MGG_09346 MGG_09346 MGG_09837 MGG_09837 MGG_04150 MGG_04150 MGG_04148 MGG_04148 MGG_02634 MGG_02634 MGG_03088 MGG_03088 MGG_10585 MGG_10585 MGCH7_ch7g721 MGCH7_ch7g721 SNF7 SNF7 END3 END3 SAR1 SAR1 ATG9 ATG9 SNX4 SNX4 MGG_10930 MGG_10930 VPS27 VPS27 SEC24 SEC24 VMA21 VMA21 SEC23 SEC23 PAN1 PAN1 SEC31 SEC31 SEC13 SEC13 HSE1 HSE1 VRG4 VRG4 MGG_02515 MGG_02515 MGG_06649 MGG_06649 MGG_06670 MGG_06670 MGG_06787 MGG_06787 MGG_05484 MGG_05484 MGG_16389 MGG_16389 MGG_06860 MGG_06860 MGG_06876 MGG_06876 MGG_06883 MGG_06883 MGG_11801 MGG_11801 MGG_05626 MGG_05626 MGG_05676 MGG_05676 MGG_13168 MGG_13168 MGG_09210 MGG_09210 MGG_05755 MGG_05755 MGG_09271 MGG_09271 MGG_10633 MGG_10633 MGG_09294 MGG_09294 MGG_04778 MGG_04778 MGG_02386 MGG_02386 MGG_02434 MGG_02434 MGG_09932 MGG_09932 MGG_10504 MGG_10504 MGG_04555 MGG_04555 MGG_01472 MGG_01472 MGG_01574 MGG_01574 MGG_07255 MGG_07255 MGG_07284 MGG_07284 MGG_01704 MGG_01704 MGG_08868 MGG_08868 MGG_14757 MGG_14757 MGG_01762 MGG_01762 MGG_01185 MGG_01185 MGG_08061 MGG_08061 MGG_10448 MGG_10448 MGG_01331 MGG_01331 MGG_11227 MGG_11227 MGG_01348 MGG_01348 MGG_08175 MGG_08175 MGG_08176 MGG_08176 MGG_07035 MGG_07035 PSD2 PSD2 MGG_07382 MGG_07382 MGG_13014 MGG_13014 MGG_13013 MGG_13013 MGG_07768 MGG_07768 MGG_07481 MGG_07481 MGG_07524 MGG_07524 MGG_09493 MGG_09493 MGG_07916 MGG_07916 MGG_05208 MGG_05208 MGG_06078 MGG_06078 MGG_05291 MGG_05291 MGG_06569 MGG_06569 MGG_03694 MGG_03694 MGG_12828 MGG_12828 MGG_12832 MGG_12832 MGG_03568 MGG_03568 MGG_06335 MGG_06335 MGG_03511 MGG_03511 MGG_03320 MGG_03320 MGG_17317 MGG_17317 MGG_01124 MGG_01124
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG18Autophagy-related protein 18; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation- induced autophagy. Involved in correct ATG9 trafficking to the pre- autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). (469 aa)
MGG_01031Vacuolar protein-sorting-associated protein 25. (224 aa)
MGG_04174SNF7 family protein. (493 aa)
MGG_04054Vacuolar protein sorting 55 superfamily protein. (129 aa)
MGG_04050Protein transporter SEC22; Belongs to the synaptobrevin family. (216 aa)
MGG_03971Uncharacterized protein. (248 aa)
MGG_03919HET-C protein. (782 aa)
MGG_09383NIMA-interacting protein TinC. (916 aa)
MGG_09346Protein transport protein BOS1; SNARE required for protein transport between the ER and the Golgi complex. (251 aa)
MGG_09837Vacuolar segregation protein pep7. (743 aa)
MGG_04150AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (724 aa)
MGG_04148Rad60-SLD_2 domain-containing protein. (263 aa)
MGG_02634Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (917 aa)
MGG_03088Uncharacterized protein. (440 aa)
MGG_10585Monooxygenase. (335 aa)
MGCH7_ch7g721Sorting nexin-3. (167 aa)
SNF7Vacuolar-sorting protein SNF7; Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity). (226 aa)
END3Actin cytoskeleton-regulatory complex protein END3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (396 aa)
SAR1Small COPII coat GTPase SAR1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated trans [...] (189 aa)
ATG9Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...] (917 aa)
SNX4Sorting nexin-4; Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans- Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity). (495 aa)
MGG_10930Uncharacterized protein. (205 aa)
VPS27Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (713 aa)
SEC24Protein transport protein SEC24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (959 aa)
VMA21Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (111 aa)
SEC23Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (770 aa)
PAN1Actin cytoskeleton-regulatory complex protein PAN1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1462 aa)
SEC31Protein transport protein SEC31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1269 aa)
SEC13Protein transport protein SEC13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (289 aa)
HSE1Class E vacuolar protein-sorting machinery protein HSE1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB). (718 aa)
VRG4GDP-mannose transporter; Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen. (394 aa)
MGG_02515Charged multivesicular body protein 6. (202 aa)
MGG_06649EF hand domain-containing protein. (1300 aa)
MGG_06670Charged multivesicular body protein 3. (234 aa)
MGG_06787Uncharacterized protein. (421 aa)
MGG_05484AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (437 aa)
MGG_16389IPPc domain-containing protein. (1076 aa)
MGG_06860Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (958 aa)
MGG_06876Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (234 aa)
MGG_06883t-SNARE; Belongs to the syntaxin family. (357 aa)
MGG_11801AP-1 complex subunit gamma. (845 aa)
MGG_05626Cytoskeleton assembly control protein SLA1p. (1155 aa)
MGG_05676Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (514 aa)
MGG_13168Uncharacterized protein. (707 aa)
MGG_09210Ssh-4. (504 aa)
MGG_05755Vacuolar fusion protein mon-1. (630 aa)
MGG_09271Uncharacterized protein. (398 aa)
MGG_10633AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (448 aa)
MGG_09294Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (203 aa)
MGG_04778Uncharacterized protein. (488 aa)
MGG_02386Uncharacterized protein. (354 aa)
MGG_02434AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (187 aa)
MGG_09932Uncharacterized protein. (732 aa)
MGG_10504Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (855 aa)
MGG_04555Triacylglycerol lipase FGL2. (393 aa)
MGG_01472Arf GTPase-activating protein. (490 aa)
MGG_01574ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (183 aa)
MGG_07255E3 ubiquitin-protein ligase. (816 aa)
MGG_07284Target-rapamycin complex subunit LST8. (317 aa)
MGG_01704Vacuolar protein-sorting-associated protein 36. (647 aa)
MGG_08868Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (249 aa)
MGG_147571-phosphatidylinositol-3-phosphate 5-kinase FAB1. (2515 aa)
MGG_01762AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
MGG_01185GTP-binding protein ypt5. (221 aa)
MGG_08061Uncharacterized protein. (645 aa)
MGG_10448ENTH domain-containing protein. (554 aa)
MGG_01331Vacuolar protein sorting 53. (838 aa)
MGG_11227AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (155 aa)
MGG_01348Uncharacterized protein. (862 aa)
MGG_08175PQ loop repeat protein. (304 aa)
MGG_08176Uncharacterized protein. (251 aa)
MGG_07035Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (297 aa)
PSD2Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1171 aa)
MGG_07382Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (729 aa)
MGG_13014Class V chitin synthase. (1787 aa)
MGG_13013Chitin synthase 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1872 aa)
MGG_07768Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1680 aa)
MGG_07481AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1033 aa)
MGG_07524Uncharacterized protein. (415 aa)
MGG_09493AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (989 aa)
MGG_07916Vacuolar protein sorting-associated protein 4; Belongs to the AAA ATPase family. (427 aa)
MGG_05208DOA4-independent degradation protein 4. (220 aa)
MGG_06078Adaptin ear-binding coat-associated protein 2. (277 aa)
MGG_05291Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
MGG_06569Transporter sec24. (1034 aa)
MGG_03694Beclin-1. (503 aa)
MGG_12828Lipase_3 domain-containing protein. (639 aa)
MGG_12832Sorting nexin-41. (627 aa)
MGG_03568Vacuole morphology and inheritance protein 14. (910 aa)
MGG_06335Calpain-7; Belongs to the peptidase C2 family. (898 aa)
MGG_03511Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1220 aa)
MGG_03320AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (738 aa)
MGG_17317Uncharacterized protein. (996 aa)
MGG_01124Vesicle transport V-SNARE protein vti1. (233 aa)
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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