(18 nodes) Regulation of transcription elongation from RNA polymerase II promoter network (Pyricularia oryzae)

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Your Input:
	MGG_16287	Uncharacterized protein. (414 aa)
	MGG_06928	CMGC/CDK protein kinase. (555 aa)
	MGG_15720	CDC73_C domain-containing protein. (421 aa)
	MGG_07291	CMGC/CDK/CRK7 protein kinase. (1198 aa)
	MGG_00958	Plus3 domain-containing protein. (591 aa)
	MGG_07316	FACT complex subunit spt-16. (1034 aa)
	MGG_01817	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (768 aa)
	MGG_11130	Uncharacterized protein. (712 aa)
	MGG_05638	Uncharacterized protein. (143 aa)
	MGG_12268	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1026 aa)
	MGG_01380	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (430 aa)
	MGG_13401	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (410 aa)
	MGG_14848	Prefoldin. (150 aa)
	MGG_00632	Cell differentiation protein rcd1. (364 aa)
	MGG_00330	26S protease subunit rpt4; Belongs to the AAA ATPase family. (391 aa)
	MGG_06943	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (122 aa)
	MGG_11491	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1407 aa)
	MGG_04133	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (534 aa)

Your Current Organism:

Pyricularia oryzae

NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MGG_00330	MGG_01380	G4NCY2	G4MZ45	26S protease subunit rpt4; Belongs to the AAA ATPase family.	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	0.999
MGG_00958	MGG_01817	G4ND66	G4MW62	Plus3 domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.407
MGG_00958	MGG_05638	G4ND66	G4MNK9	Plus3 domain-containing protein.	Uncharacterized protein.	0.830
MGG_00958	MGG_06943	G4ND66	G4MNF7	Plus3 domain-containing protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.942
MGG_00958	MGG_07316	G4ND66	G4MV07	Plus3 domain-containing protein.	FACT complex subunit spt-16.	0.970
MGG_00958	MGG_11491	G4ND66	G4NEB7	Plus3 domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.940
MGG_00958	MGG_12268	G4ND66	G4MXS4	Plus3 domain-containing protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.985
MGG_00958	MGG_15720	G4ND66	G4MT03	Plus3 domain-containing protein.	CDC73_C domain-containing protein.	0.997
MGG_00958	MGG_16287	G4ND66	G4MR31	Plus3 domain-containing protein.	Uncharacterized protein.	0.997
MGG_01380	MGG_00330	G4MZ45	G4NCY2	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	26S protease subunit rpt4; Belongs to the AAA ATPase family.	0.999
MGG_01817	MGG_00958	G4MW62	G4ND66	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Plus3 domain-containing protein.	0.407
MGG_01817	MGG_06943	G4MW62	G4MNF7	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.533
MGG_01817	MGG_07316	G4MW62	G4MV07	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	FACT complex subunit spt-16.	0.469
MGG_01817	MGG_11130	G4MW62	G4MW77	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.574
MGG_01817	MGG_12268	G4MW62	G4MXS4	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.586
MGG_01817	MGG_13401	G4MW62	G4N1L4	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	0.490
MGG_04133	MGG_07316	G4NIS4	G4MV07	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	FACT complex subunit spt-16.	0.477
MGG_05638	MGG_00958	G4MNK9	G4ND66	Uncharacterized protein.	Plus3 domain-containing protein.	0.830
MGG_05638	MGG_06943	G4MNK9	G4MNF7	Uncharacterized protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.873
MGG_05638	MGG_07316	G4MNK9	G4MV07	Uncharacterized protein.	FACT complex subunit spt-16.	0.944