node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HTB1 | MGG_09555 | P0CT13 | G4N1A8 | Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.567 |
HTB1 | MGG_11757 | P0CT13 | G4MPV1 | Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | DNA damage response protein RcaA. | 0.550 |
MGCH7_ch7g688 | MGG_00485 | G5EH81 | G4NBT5 | Sister chromatid cohesion protein Eso1. | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | 0.958 |
MGCH7_ch7g688 | MGG_00518 | G5EH81 | G4NBP7 | Sister chromatid cohesion protein Eso1. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.999 |
MGCH7_ch7g688 | MGG_00519 | G5EH81 | G4NBP6 | Sister chromatid cohesion protein Eso1. | Vezatin domain-containing protein. | 0.999 |
MGCH7_ch7g688 | MGG_01470 | G5EH81 | G4MSK5 | Sister chromatid cohesion protein Eso1. | RECA_2 domain-containing protein. | 0.833 |
MGCH7_ch7g688 | MGG_07124 | G5EH81 | G4MT45 | Sister chromatid cohesion protein Eso1. | Replication protein A 32 kDa subunit. | 0.964 |
MGCH7_ch7g688 | MGG_09555 | G5EH81 | G4N1A8 | Sister chromatid cohesion protein Eso1. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.538 |
MGCH7_ch7g688 | MGG_10060 | G5EH81 | G4N932 | Sister chromatid cohesion protein Eso1. | ABC-type Fe3+ transport system. | 0.932 |
MGCH7_ch7g688 | MGG_11342 | G5EH81 | G4MUA4 | Sister chromatid cohesion protein Eso1. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.753 |
MGCH7_ch7g688 | MGG_11757 | G5EH81 | G4MPV1 | Sister chromatid cohesion protein Eso1. | DNA damage response protein RcaA. | 0.473 |
MGCH7_ch7g688 | MGG_15281 | G5EH81 | G4N7F9 | Sister chromatid cohesion protein Eso1. | SMC_N domain-containing protein. | 0.932 |
MGCH7_ch7g688 | MSH3 | G5EH81 | A4R0R0 | Sister chromatid cohesion protein Eso1. | DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] | 0.613 |
MGG_00485 | MGCH7_ch7g688 | G4NBT5 | G5EH81 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | Sister chromatid cohesion protein Eso1. | 0.958 |
MGG_00485 | MGG_00518 | G4NBT5 | G4NBP7 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.860 |
MGG_00485 | MGG_00519 | G4NBT5 | G4NBP6 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | Vezatin domain-containing protein. | 0.860 |
MGG_00485 | MGG_01470 | G4NBT5 | G4MSK5 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | RECA_2 domain-containing protein. | 0.526 |
MGG_00485 | MGG_07124 | G4NBT5 | G4MT45 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | Replication protein A 32 kDa subunit. | 0.607 |
MGG_00518 | MGCH7_ch7g688 | G4NBP7 | G5EH81 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Sister chromatid cohesion protein Eso1. | 0.999 |
MGG_00518 | MGG_00485 | G4NBP7 | G4NBT5 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | 0.860 |