STRINGSTRING
HTB1 HTB1 MSH3 MSH3 MGG_11757 MGG_11757 MGG_01470 MGG_01470 MGG_07124 MGG_07124 MGG_11342 MGG_11342 MGG_01829 MGG_01829 MGG_09555 MGG_09555 MGG_03729 MGG_03729 MGG_15281 MGG_15281 MGG_06387 MGG_06387 MGG_10060 MGG_10060 MGG_00519 MGG_00519 MGG_00518 MGG_00518 MGG_00485 MGG_00485 MGG_04208 MGG_04208 MGG_12138 MGG_12138 MGCH7_ch7g688 MGCH7_ch7g688
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HTB1Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (137 aa)
MSH3DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] (1151 aa)
MGG_11757DNA damage response protein RcaA. (881 aa)
MGG_01470RECA_2 domain-containing protein. (387 aa)
MGG_07124Replication protein A 32 kDa subunit. (275 aa)
MGG_11342DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (669 aa)
MGG_01829XPG_I_2 domain-containing protein. (620 aa)
MGG_09555Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (731 aa)
MGG_03729CAMK/CAMKL/CHK1 protein kinase. (551 aa)
MGG_15281SMC_N domain-containing protein. (1186 aa)
MGG_06387WD repeat-containing protein 70. (584 aa)
MGG_10060ABC-type Fe3+ transport system. (360 aa)
MGG_00519Vezatin domain-containing protein. (623 aa)
MGG_00518Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
MGG_00485DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1201 aa)
MGG_04208Uncharacterized protein. (296 aa)
MGG_12138Checkpoint protein; Belongs to the HUS1 family. (371 aa)
MGCH7_ch7g688Sister chromatid cohesion protein Eso1. (668 aa)
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
Server load: low (14%) [HD]