(13 nodes) Mitotic DNA damage checkpoint signaling network (Pyricularia oryzae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MGG_12138	Checkpoint protein; Belongs to the HUS1 family. (371 aa)
	MGG_11757	DNA damage response protein RcaA. (881 aa)
	MGG_02428	ERCC4 domain-containing protein. (750 aa)
	MGG_04585	Crossover junction endonuclease MUS81. (594 aa)
	MGG_04790	CAMK/RAD53 protein kinase. (1175 aa)
	MGG_01756	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
	MGG_01813	MRC1 domain-containing protein. (1407 aa)
	MGG_08340	Uncharacterized protein. (416 aa)
	MGG_09555	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (731 aa)
	MGG_05040	Uncharacterized protein. (918 aa)
	MGG_05278	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (454 aa)
	MGG_03729	CAMK/CAMKL/CHK1 protein kinase. (551 aa)
	MGG_04208	Uncharacterized protein. (296 aa)

Your Current Organism:

Pyricularia oryzae

NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MGG_01813	MGG_03729	G4MW58	G4N6G2	MRC1 domain-containing protein.	CAMK/CAMKL/CHK1 protein kinase.	0.560
MGG_01813	MGG_04790	G4MW58	G4MTT5	MRC1 domain-containing protein.	CAMK/RAD53 protein kinase.	0.939
MGG_01813	MGG_05278	G4MW58	G4N5P0	MRC1 domain-containing protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.692
MGG_02428	MGG_04585	G4MRH6	G4MSU8	ERCC4 domain-containing protein.	Crossover junction endonuclease MUS81.	0.919
MGG_03729	MGG_01813	G4N6G2	G4MW58	CAMK/CAMKL/CHK1 protein kinase.	MRC1 domain-containing protein.	0.560
MGG_03729	MGG_04208	G4N6G2	G4NF89	CAMK/CAMKL/CHK1 protein kinase.	Uncharacterized protein.	0.626
MGG_03729	MGG_04585	G4N6G2	G4MSU8	CAMK/CAMKL/CHK1 protein kinase.	Crossover junction endonuclease MUS81.	0.631
MGG_03729	MGG_04790	G4N6G2	G4MTT5	CAMK/CAMKL/CHK1 protein kinase.	CAMK/RAD53 protein kinase.	0.892
MGG_03729	MGG_05040	G4N6G2	G4N3W8	CAMK/CAMKL/CHK1 protein kinase.	Uncharacterized protein.	0.866
MGG_03729	MGG_05278	G4N6G2	G4N5P0	CAMK/CAMKL/CHK1 protein kinase.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.839
MGG_03729	MGG_09555	G4N6G2	G4N1A8	CAMK/CAMKL/CHK1 protein kinase.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.737
MGG_03729	MGG_11757	G4N6G2	G4MPV1	CAMK/CAMKL/CHK1 protein kinase.	DNA damage response protein RcaA.	0.630
MGG_03729	MGG_12138	G4N6G2	G4NGQ2	CAMK/CAMKL/CHK1 protein kinase.	Checkpoint protein; Belongs to the HUS1 family.	0.649
MGG_04208	MGG_03729	G4NF89	G4N6G2	Uncharacterized protein.	CAMK/CAMKL/CHK1 protein kinase.	0.626
MGG_04208	MGG_05040	G4NF89	G4N3W8	Uncharacterized protein.	Uncharacterized protein.	0.697
MGG_04208	MGG_05278	G4NF89	G4N5P0	Uncharacterized protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.951
MGG_04208	MGG_09555	G4NF89	G4N1A8	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.640
MGG_04208	MGG_11757	G4NF89	G4MPV1	Uncharacterized protein.	DNA damage response protein RcaA.	0.591
MGG_04585	MGG_02428	G4MSU8	G4MRH6	Crossover junction endonuclease MUS81.	ERCC4 domain-containing protein.	0.919
MGG_04585	MGG_03729	G4MSU8	G4N6G2	Crossover junction endonuclease MUS81.	CAMK/CAMKL/CHK1 protein kinase.	0.631