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TOA2 TOA2 MGG_01817 MGG_01817 MGCH7_ch7g579 MGCH7_ch7g579 MGG_00780 MGG_00780 MGG_11491 MGG_11491 MGG_00908 MGG_00908 MGG_00330 MGG_00330 MGG_12925 MGG_12925 MGG_14751 MGG_14751 MGG_01380 MGG_01380 MGG_04989 MGG_04989
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TOA2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with tbp mediates transcriptional activity (By similarity). (116 aa)
MGG_01817Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (768 aa)
MGCH7_ch7g579Negative cofactor 2 complex subunit beta. (138 aa)
MGG_00780PC4 domain-containing protein. (162 aa)
MGG_11491Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1407 aa)
MGG_0090826S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (421 aa)
MGG_0033026S protease subunit rpt4; Belongs to the AAA ATPase family. (391 aa)
MGG_1292526S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (464 aa)
MGG_14751FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (556 aa)
MGG_0138026S protease regulatory subunit 8; Belongs to the AAA ATPase family. (430 aa)
MGG_04989TATA-binding protein-associated factor MOT1. (1893 aa)
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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