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MGG_09554 | Anaphase-promoting complex subunit 10. (359 aa) | ||||
SDS23 | Protein SDS23; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (534 aa) | ||||
GET3 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (343 aa) | ||||
IML1 | Vacuolar membrane-associated protein IML1. (1874 aa) | ||||
YPI1 | Type 1 phosphatases regulator YPI1; Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control; Belongs to the YPI1 family. (193 aa) | ||||
SSN8 | RNA polymerase II holoenzyme cyclin-like subunit; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By s [...] (363 aa) | ||||
MGG_02492 | Uncharacterized protein. (386 aa) | ||||
MGG_04418 | Uncharacterized protein. (541 aa) | ||||
MGG_06640 | Uncharacterized protein. (221 aa) | ||||
MGG_06648 | Uncharacterized protein. (1004 aa) | ||||
MGG_06654 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (267 aa) | ||||
MGG_05379 | Vacuolar protein sorting-associated protein 9. (747 aa) | ||||
MGG_13036 | Uncharacterized protein. (332 aa) | ||||
MGG_08627 | Sec2p domain-containing protein. (318 aa) | ||||
MGG_08631 | Methionine adenosyltransferase 2 subunit beta. (315 aa) | ||||
MGG_06700 | TBC domain-containing protein. (982 aa) | ||||
MGG_16345 | Uncharacterized protein. (97 aa) | ||||
MGG_05437 | Uncharacterized protein. (77 aa) | ||||
MGG_05448 | BAG domain-containing protein. (351 aa) | ||||
MGG_06787 | Uncharacterized protein. (421 aa) | ||||
MGG_06824 | Uncharacterized protein. (208 aa) | ||||
MGG_05522 | Uncharacterized protein. (246 aa) | ||||
MGG_01969 | Uncharacterized protein. (1584 aa) | ||||
MGG_01976 | TBC1 domain family member 14. (766 aa) | ||||
MGG_11817 | C-type cyclin; Belongs to the cyclin family. (493 aa) | ||||
MGG_06844 | Uncharacterized protein. (281 aa) | ||||
MGG_15176 | Cyclin-H. (397 aa) | ||||
MGG_06874 | TBC1 domain family member 22A. (582 aa) | ||||
MGG_06892 | WD repeat-containing protein srw1. (604 aa) | ||||
MGG_06905 | Protein transporter sec73. (1529 aa) | ||||
MGG_05609 | Uncharacterized protein. (565 aa) | ||||
MGG_02088 | Uncharacterized protein. (613 aa) | ||||
MGG_06933 | Calcineurin subunit B. (174 aa) | ||||
MGG_05637 | Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (481 aa) | ||||
MGG_05646 | G2/mitotic-specific cyclin-B; Belongs to the cyclin family. (494 aa) | ||||
MGG_05651 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (273 aa) | ||||
MGG_02099 | C2 domain-containing protein. (703 aa) | ||||
MGG_11784 | Uncharacterized protein. (1202 aa) | ||||
MGG_05662 | Shwachman-Bodian-Diamond syndrome protein. (320 aa) | ||||
MGG_05671 | Protein phosphatase PP2A regulatory subunit A. (623 aa) | ||||
MGG_05699 | RIC1 domain-containing protein. (1118 aa) | ||||
MGG_05738 | Paxillin. (925 aa) | ||||
MGG_09261 | Uncharacterized protein. (322 aa) | ||||
MGG_09275 | Uncharacterized protein. (1535 aa) | ||||
MGG_09303 | Rho-GAP domain-containing protein. (751 aa) | ||||
MGG_04778 | Uncharacterized protein. (488 aa) | ||||
MGG_04719 | Guanine nucleotide-binding protein subunit beta-like protein. (316 aa) | ||||
MGG_09882 | Uncharacterized protein. (348 aa) | ||||
MGG_04710 | Translational activator GCN1. (2678 aa) | ||||
MGG_04694 | Trafficking protein particle complex subunit BET3. (192 aa) | ||||
MGG_04676 | Mitotic check point protein BUB2. (503 aa) | ||||
MGG_02419 | Guanine nucleotide exchange factor LTE1. (1863 aa) | ||||
MGG_09935 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (449 aa) | ||||
MGG_09954 | RSP. (1048 aa) | ||||
MGG_10646 | Protoplast regeneration and killer toxin resistance. (818 aa) | ||||
MGG_04564 | DUF1752 domain-containing protein. (557 aa) | ||||
MGG_04551 | Proteasome subunit beta. (206 aa) | ||||
MGG_04507 | Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (149 aa) | ||||
MGG_04436 | Elongation factor 1-beta; Belongs to the EF-1-beta/EF-1-delta family. (229 aa) | ||||
MGG_15540 | RPN13_C domain-containing protein. (387 aa) | ||||
MGG_01437 | Cyclin domain-containing protein. (334 aa) | ||||
MGG_01444 | Uncharacterized protein. (220 aa) | ||||
MGG_01472 | Arf GTPase-activating protein. (490 aa) | ||||
MGG_07065 | G2/mitotic-specific cyclin-B; Belongs to the cyclin family. (657 aa) | ||||
MGG_12336 | Pattern formation protein EMB30. (1638 aa) | ||||
MGG_01489 | Uncharacterized protein. (979 aa) | ||||
MGG_14517 | Developmental regulator flbA. (714 aa) | ||||
MGG_07120 | 26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (897 aa) | ||||
MGG_07137 | Rab GDP dissociation inhibitor; Belongs to the Rab GDI family. (464 aa) | ||||
MGG_04661 | SCA7 domain-containing protein. (459 aa) | ||||
MGG_04675 | Uncharacterized protein. (372 aa) | ||||
MGG_01550 | Calcium-binding protein NCS-1. (190 aa) | ||||
MGG_15867 | Uncharacterized protein. (923 aa) | ||||
MGG_07193 | WW domain-containing protein. (366 aa) | ||||
MGG_04788 | Uncharacterized protein. (1128 aa) | ||||
MGG_01589 | Uncharacterized protein. (100 aa) | ||||
MGG_01597 | ARF GTPase activator. (1126 aa) | ||||
MGG_11178 | DH domain-containing protein. (2004 aa) | ||||
MGG_07243 | Uncharacterized protein. (676 aa) | ||||
MGG_07265 | mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (166 aa) | ||||
MGG_07284 | Target-rapamycin complex subunit LST8. (317 aa) | ||||
MGG_10159 | Mitochondrial import inner membrane translocase subunit tim-14. (106 aa) | ||||
MGG_10160 | Ribosome biogenesis protein RLP24. (229 aa) | ||||
MGG_10179 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (90 aa) | ||||
MGG_01689 | Rho GDP dissociation inhibitor. (199 aa) | ||||
MGG_01695 | DH domain-containing protein. (1517 aa) | ||||
MGG_12396 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (122 aa) | ||||
MGG_08866 | Eukaryotic translation initiation factor 5. (430 aa) | ||||
MGG_01717 | Uncharacterized protein. (686 aa) | ||||
MGG_01745 | Zinc finger protein gcs1. (403 aa) | ||||
MGG_15323 | Vacuolar protein-sorting protein bro-1. (1027 aa) | ||||
MGG_01765 | Uncharacterized protein. (304 aa) | ||||
MGG_11144 | Chaperone dnaJ. (543 aa) | ||||
MGG_01835 | Inner centromere protein. (1378 aa) | ||||
MGG_01843 | Phosphatidylethanolamine-binding protein. (200 aa) | ||||
MGG_08980 | Stress-induced-phosphoprotein 1. (584 aa) | ||||
MGG_08339 | F-box domain-containing protein. (377 aa) | ||||
MGG_01236 | WD repeat-containing protein slp1. (593 aa) | ||||
MGG_01248 | Ran GTPase-activating protein 1. (421 aa) | ||||
MGG_14774 | Uncharacterized protein. (169 aa) | ||||
MGG_01258 | Cyclin-K; Belongs to the cyclin family. (486 aa) | ||||
MGG_08105 | GTPase activating protein. (1109 aa) | ||||
MGG_10843 | SIL1. (413 aa) | ||||
MGG_01345 | Glutamate-cysteine ligase modifier subunit. (359 aa) | ||||
MGG_10958 | VPS9 domain-containing protein. (1308 aa) | ||||
MGG_01361 | PHO85 cyclin-1. (353 aa) | ||||
MGG_04377 | Rho-type GTPase-activating protein 1. (1181 aa) | ||||
MGG_04388 | Ubiquitin-conjugating enzyme E2Z. (446 aa) | ||||
MGG_01399 | Lipid binding protein. (250 aa) | ||||
MGG_01419 | Small nuclear ribonucleoprotein U1a. (1329 aa) | ||||
MGG_07031 | Proteasome subunit beta. (203 aa) | ||||
MGG_07061 | Uncharacterized protein. (674 aa) | ||||
MGG_06154 | Ras-like protein. (214 aa) | ||||
MGG_06158 | Uncharacterized protein. (469 aa) | ||||
MGG_06185 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (109 aa) | ||||
MGG_12886 | Uncharacterized protein. (284 aa) | ||||
MGG_07715 | GH16 domain-containing protein. (258 aa) | ||||
MGG_06198 | Uncharacterized protein. (712 aa) | ||||
MGG_06201 | Inhibitor I9 domain-containing protein. (116 aa) | ||||
MGG_07733 | Clock-controlled pheromone ccg-4. (321 aa) | ||||
MGG_07744 | CwfJ domain-containing protein. (543 aa) | ||||
MGG_09531 | Rho-GTPase-activating protein 8. (891 aa) | ||||
MGG_09525 | Impact family protein. (293 aa) | ||||
MGG_09499 | Ras-2. (241 aa) | ||||
MGG_07561 | Uncharacterized protein. (1000 aa) | ||||
MGG_07913 | Uncharacterized protein. (1761 aa) | ||||
MGG_04906 | muHD domain-containing protein. (774 aa) | ||||
MGG_13439 | Uncharacterized protein. (320 aa) | ||||
MGG_04954 | Stromal membrane-associated protein 1. (574 aa) | ||||
MGG_05852 | HET domain-containing protein. (319 aa) | ||||
MGG_05007 | Uncharacterized protein. (664 aa) | ||||
MGG_05901 | Uncharacterized protein. (327 aa) | ||||
MGG_13245 | Translation regulator GCD7; Belongs to the eIF-2B alpha/beta/delta subunits family. (448 aa) | ||||
MGG_05951 | Uncharacterized protein. (720 aa) | ||||
MGG_05991 | 26S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1192 aa) | ||||
MGG_16736 | Uncharacterized protein. (121 aa) | ||||
MGG_06021 | Rab-GAP TBC domain-containing protein. (435 aa) | ||||
MGG_06028 | WD_REPEATS_REGION domain-containing protein. (534 aa) | ||||
MGG_05199 | Protein kinase regulator Ste50. (489 aa) | ||||
MGG_05202 | Uncharacterized protein. (406 aa) | ||||
MGG_05203 | Ran-specific GTPase-activating protein 1. (247 aa) | ||||
MGG_05216 | Rab-GAP TBC domain-containing protein. (821 aa) | ||||
MGG_06077 | Translation initiation factor eIF-2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (339 aa) | ||||
MGG_05258 | Mitochondrial-processing peptidase subunit alpha; Belongs to the peptidase M16 family. (561 aa) | ||||
MGG_16762 | Uncharacterized protein; Belongs to the actin family. (771 aa) | ||||
MGG_06138 | SMK-1 domain-containing protein. (869 aa) | ||||
MGG_05278 | DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (454 aa) | ||||
MGG_05280 | NADPH oxidase regulator NoxR. (525 aa) | ||||
MGG_05284 | Cytosolic regulator Pianissimo. (1396 aa) | ||||
MGG_08558 | Nuc-1 negative regulatory protein preg. (442 aa) | ||||
MGG_08589 | AB hydrolase-1 domain-containing protein. (368 aa) | ||||
MGG_14008 | Uncharacterized protein. (476 aa) | ||||
MGG_03709 | J domain-containing protein. (820 aa) | ||||
MGG_03700 | Uncharacterized protein. (1672 aa) | ||||
MGG_06519 | WD domain-containing protein. (830 aa) | ||||
MGG_06504 | 26S proteasome regulatory subunit RPN7. (496 aa) | ||||
MGG_06476 | VPS9 domain-containing protein. (721 aa) | ||||
MGG_03649 | Protein phosphatase 1 regulatory subunit SDS22. (381 aa) | ||||
MGG_03644 | Uncharacterized protein. (144 aa) | ||||
MGG_06435 | Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (162 aa) | ||||
MGG_03605 | CDK-activating kinase assembly factor MAT1. (360 aa) | ||||
MGG_03595 | G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (406 aa) | ||||
MGG_06390 | Rho-GAP domain-containing protein. (821 aa) | ||||
MGG_03565 | DnaJ and TPR domain-containing protein. (529 aa) | ||||
MGG_03517 | W2 domain-containing protein. (733 aa) | ||||
MGG_12708 | Uncharacterized protein. (284 aa) | ||||
MGG_12709 | Uncharacterized protein. (970 aa) | ||||
MGG_13576 | RCC1 domain-containing protein. (919 aa) | ||||
MGG_03275 | Uncharacterized protein; Belongs to the DOCK family. (2149 aa) | ||||
MGG_03254 | TBC1 domain family member 10A. (1118 aa) | ||||
MGG_03253 | GTPase-activating protein GYP5. (942 aa) | ||||
MGG_03219 | Conidiophore development protein hymA. (371 aa) | ||||
MGG_03218 | Uncharacterized protein. (260 aa) | ||||
MGG_03214 | GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (252 aa) | ||||
MGG_14823 | Uncharacterized protein. (724 aa) | ||||
MGG_17271 | Uncharacterized protein. (338 aa) | ||||
MGG_09697 | Rho guanine nucleotide exchange factor scd1. (1051 aa) | ||||
MGG_03162 | Uncharacterized protein. (1009 aa) | ||||
MGG_03151 | Maintenance-ploidy protein mob1. (219 aa) | ||||
MGG_00682 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (119 aa) | ||||
MGG_00597 | Hsk1-interacting molecule 1. (668 aa) | ||||
MGG_00544 | Uncharacterized protein. (195 aa) | ||||
MGG_00519 | Vezatin domain-containing protein. (623 aa) | ||||
MGG_00518 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa) | ||||
MGG_14234 | Uncharacterized protein. (454 aa) | ||||
MGG_00454 | Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (955 aa) | ||||
MGG_00448 | RanGTP-binding protein. (633 aa) | ||||
MGG_00446 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (351 aa) | ||||
MGG_11425 | Ras-GAP domain-containing protein. (2615 aa) | ||||
MGG_01106 | DDENN domain-containing protein. (1023 aa) | ||||
MGG_01104 | Acetolactate synthase small subunit. (316 aa) | ||||
MGG_00408 | RCC1 domain-containing protein. (669 aa) | ||||
MGG_00397 | RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (490 aa) | ||||
MGG_01064 | Uncharacterized protein. (98 aa) | ||||
MGG_01054 | Vacuolar morphogenesis protein AvaB. (1049 aa) | ||||
MGG_00371 | Cell division control protein 25. (1208 aa) | ||||
MGG_14699 | DnaJ domain-containing protein. (300 aa) | ||||
MGG_00318 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (886 aa) | ||||
MGG_00928 | Sec7 domain-containing protein. (1595 aa) | ||||
MGG_00926 | WD_REPEATS_REGION domain-containing protein. (986 aa) | ||||
MGG_00909 | UDENN FLCN/SMCR8-type domain-containing protein. (482 aa) | ||||
MGG_00254 | Ornithine decarboxylase antizyme. (296 aa) | ||||
MGG_00899 | Tubulin-specific chaperone C. (351 aa) | ||||
MGG_00884 | 26S proteasome non-ATPase regulatory subunit 3. (557 aa) | ||||
MGG_17505 | AAA family ATPase. (575 aa) | ||||
MGG_00199 | Uncharacterized protein. (1295 aa) | ||||
MGG_00867 | Uncharacterized protein. (199 aa) | ||||
MGG_00134 | Von Willebrand RING finger domain-containing protein. (1161 aa) | ||||
MGG_00814 | Hsp90-like protein. (327 aa) | ||||
MGG_00118 | Rab-GAP TBC domain-containing protein. (1238 aa) | ||||
MGG_00082 | HET domain-containing protein. (782 aa) | ||||
MGG_17372 | Uncharacterized protein. (185 aa) | ||||
MGG_00757 | Cell division control protein 14. (299 aa) | ||||
MGG_00737 | Uncharacterized protein. (150 aa) | ||||
MGG_00708 | Trafficking protein particle complex subunit; Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. (216 aa) | ||||
MGG_04196 | Rab-GAP TBC domain-containing protein. (1131 aa) | ||||
MGG_04186 | Rho GTPase activator Rga. (1164 aa) | ||||
MGG_04246 | Uncharacterized protein. (143 aa) | ||||
MGG_14151 | Uncharacterized protein. (615 aa) | ||||
MGG_08772 | Uncharacterized protein. (306 aa) | ||||
MGG_17579 | Uncharacterized protein. (157 aa) | ||||
MGG_04342 | Proteasome activator subunit 4. (1849 aa) | ||||
MGG_04320 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (493 aa) | ||||
MGG_17690 | ER membrane protein. (456 aa) | ||||
MGG_04067 | GTPase-activating protein GYP7. (833 aa) | ||||
MGG_17698 | Uncharacterized protein. (1438 aa) | ||||
MGG_17708 | Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (491 aa) | ||||
MGG_12130 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (670 aa) | ||||
MGG_04006 | Rho-GAP domain-containing protein. (1347 aa) | ||||
MGG_04005 | Nuclear protein SNF4. (383 aa) | ||||
MGG_03993 | Rap-GAP domain-containing protein. (1665 aa) | ||||
MGG_03983 | Hsp70-like protein. (217 aa) | ||||
MGG_12117 | SH3 domain-containing protein. (1334 aa) | ||||
MGG_03846 | GTPase-activating protein. (779 aa) | ||||
MGG_14173 | Transporter SEC7. (1872 aa) | ||||
MGG_12164 | NOT2_3_5 domain-containing protein. (481 aa) | ||||
MGG_02745 | Uncharacterized protein. (162 aa) | ||||
MGG_02727 | Uncharacterized protein. (216 aa) | ||||
MGG_12644 | Rho1 guanine nucleotide exchange factor 1. (1680 aa) | ||||
MGG_03064 | Rho1 guanine nucleotide exchange factor 1. (1281 aa) | ||||
MGG_03048 | Uncharacterized protein. (750 aa) | ||||
MGG_17901 | Cytochrome c oxidase subunit 6A, mitochondrial. (125 aa) | ||||
MGG_02833 | GTPase-activating protein GYP2. (1186 aa) | ||||
MGCH7_ch7g512 | Uncharacterized protein. (725 aa) | ||||
MGCH7_ch7g805 | Uncharacterized protein. (392 aa) | ||||
MGCH7_ch7g422 | Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (530 aa) | ||||
MGCH7_ch7g686 | Sec2p domain-containing protein. (669 aa) | ||||
SUM1 | cAMP-dependent protein kinase regulatory subunit. (390 aa) | ||||
ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity). (181 aa) | ||||
ATG9 | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...] (917 aa) | ||||
ATG17 | Autophagy-related protein 17; Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity); Belongs to the ATG17 family. (504 aa) | ||||
ATG5 | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1- like activating enzyme and ATG10 as an E2- [...] (314 aa) |