62 items (Pyricularia oryzae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MGG_05260	Uncharacterized protein. (1781 aa)
	MGG_08628	3'-5' exoribonuclease CSL4. (213 aa)
	MGG_08646	DNA helicase; Belongs to the MCM family. (720 aa)
	MGG_06725	Uncharacterized protein. (429 aa)
	MGG_05432	Asparaginyl-tRNA synthetase. (245 aa)
	MGG_05477	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (459 aa)
	MGG_05647	50S ribosomal protein L2. (388 aa)
	MGG_10627	ATP-dependent DNA ligase domain-containing protein. (970 aa)
	MGG_09293	DNA helicase; Belongs to the MCM family. (1029 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (815 aa)
	MGG_09894	40S ribosomal protein S28. (68 aa)
	MGG_13783	Aspartyl-tRNA synthetase. (965 aa)
	MGG_13800	Mitochondrial protein cyt-4. (1091 aa)
	MGG_02482	DNA replication licensing factor mcm10. (838 aa)
	MGG_07080	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (155 aa)
	MGG_07124	Replication protein A 32 kDa subunit. (275 aa)
	MGG_01581	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (439 aa)
	MGG_01759	DNA helicase; Belongs to the MCM family. (896 aa)
	MGG_08897	Asparaginyl-tRNA synthetase. (586 aa)
	MGG_01302	Uncharacterized protein. (387 aa)
	MGG_08084	Cell wall biogenesis protein phosphatase Ssd1. (1350 aa)
	MGG_08100	Exosome component 2. (361 aa)
	MGG_08122	DNA helicase; Belongs to the MCM family. (873 aa)
	MGG_10830	DNA-directed RNA polymerase III polypeptide. (213 aa)
	MGG_01380	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (430 aa)
	MGG_08186	Telo_bind domain-containing protein. (1870 aa)
	MGG_07061	Uncharacterized protein. (674 aa)
	MGG_09556	Mitochondrial 37S ribosomal protein S17. (169 aa)
	MGG_04941	S1-like domain-containing protein. (187 aa)
	MGG_04966	Lysine--tRNA ligase. (615 aa)
	MGG_12925	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (464 aa)
	MGG_16739	Eukaryotic translation initiation factor 5A. (164 aa)
	MGG_12899	DNA ligase. (1001 aa)
	MGG_13200	Eukaryotic translation initiation factor 2 subunit alpha. (310 aa)
	MGG_06566	Asparaginyl-tRNA synthetase. (567 aa)
	MGG_03680	40S ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (161 aa)
	MGG_12831	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (405 aa)
	MGG_06453	Uncharacterized protein. (206 aa)
	MGG_13512	Aspartyl-tRNA synthetase. (727 aa)
	MGG_06370	DNA ligase. (896 aa)
	MGG_06269	60S ribosomal protein L2. (254 aa)
	MGG_00685	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (610 aa)
	MGG_17442	Uncharacterized protein. (172 aa)
	MGG_01066	40S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (145 aa)
	MGG_01002	OB-fold nucleic acid binding domain-containing protein. (426 aa)
	MGG_00330	26S protease subunit rpt4; Belongs to the AAA ATPase family. (391 aa)
	MGG_00908	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (421 aa)
	MGG_00193	Mitotic control protein dis3; Belongs to the RNR ribonuclease family. (990 aa)
	MGG_00161	Lysyl-tRNA synthetase. (638 aa)
	MGG_11491	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1407 aa)
	MGG_08807	Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22. (1207 aa)
	MGG_08691	30S ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (174 aa)
	MGG_17596	tRNA-binding domain-containing protein. (404 aa)
	MGG_14916	Uncharacterized protein. (146 aa)
	MGG_04010	Uncharacterized protein. (113 aa)
	MGG_03881	tRNA (Uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (649 aa)
	MGG_03854	DNA ligase. (859 aa)
	MGG_17683	DNA helicase; Belongs to the MCM family. (953 aa)
	MGG_02696	Woronin body major protein. (417 aa)
	MGG_12574	Aspartyl-tRNA synthetase. (577 aa)
	MGCH7_ch7g600	Exosome complex exonuclease RRP40. (264 aa)
	MGCH7_ch7g640	Deoxyribose-phosphate aldolase 2. (347 aa)

Your Current Organism:

Pyricularia oryzae

NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	MGG_00685	G4MQQ0	G4NAX8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.782
MCM7	MGG_01759	G4MQQ0	G4MVC9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MGG_02482	G4MQQ0	G4MRZ7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication licensing factor mcm10.	0.995
MCM7	MGG_03854	G4MQQ0	G4NHG0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.695
MCM7	MGG_06370	G4MQQ0	G4N7T1	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.695
MCM7	MGG_07124	G4MQQ0	G4MT45	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication protein A 32 kDa subunit.	0.842
MCM7	MGG_08122	G4MQQ0	G4MYE0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MGG_08646	G4MQQ0	G4ML38	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MGG_09293	G4MQQ0	G4MQP3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MGG_10627	G4MQQ0	G4MQC2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	ATP-dependent DNA ligase domain-containing protein.	0.446
MCM7	MGG_12899	G4MQQ0	G4N5E4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.446
MCM7	MGG_17683	G4MQQ0	G4NIS8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MGCH7_ch7g600	MGG_00193	G5EH77	G4NDV8	Exosome complex exonuclease RRP40.	Mitotic control protein dis3; Belongs to the RNR ribonuclease family.	0.967
MGCH7_ch7g600	MGG_01066	G5EH77	G4NCJ2	Exosome complex exonuclease RRP40.	40S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.408
MGCH7_ch7g600	MGG_05260	G5EH77	G4N5F3	Exosome complex exonuclease RRP40.	Uncharacterized protein.	0.820
MGCH7_ch7g600	MGG_08084	G5EH77	G4MY97	Exosome complex exonuclease RRP40.	Cell wall biogenesis protein phosphatase Ssd1.	0.950
MGCH7_ch7g600	MGG_08100	G5EH77	G4MYB3	Exosome complex exonuclease RRP40.	Exosome component 2.	0.999
MGCH7_ch7g600	MGG_08628	G5EH77	G4ML19	Exosome complex exonuclease RRP40.	3'-5' exoribonuclease CSL4.	0.999
MGCH7_ch7g600	MGG_08807	G5EH77	G4NFJ0	Exosome complex exonuclease RRP40.	Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22.	0.428
MGCH7_ch7g600	MGG_09894	G5EH77	G4MR44	Exosome complex exonuclease RRP40.	40S ribosomal protein S28.	0.408