(6 nodes) MCM N-terminal domain network (Pyricularia oryzae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MGG_01759	DNA helicase; Belongs to the MCM family. (896 aa)
	MGG_08646	DNA helicase; Belongs to the MCM family. (720 aa)
	MGG_09293	DNA helicase; Belongs to the MCM family. (1029 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (815 aa)
	MGG_08122	DNA helicase; Belongs to the MCM family. (873 aa)
	MGG_17683	DNA helicase; Belongs to the MCM family. (953 aa)

Your Current Organism:

Pyricularia oryzae

NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	MGG_01759	G4MQQ0	G4MVC9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MGG_08122	G4MQQ0	G4MYE0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MGG_08646	G4MQQ0	G4ML38	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MGG_09293	G4MQQ0	G4MQP3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MGG_17683	G4MQQ0	G4NIS8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MGG_01759	MCM7	G4MVC9	G4MQQ0	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
MGG_01759	MGG_08122	G4MVC9	G4MYE0	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_01759	MGG_08646	G4MVC9	G4ML38	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_01759	MGG_09293	G4MVC9	G4MQP3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_01759	MGG_17683	G4MVC9	G4NIS8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_08122	MCM7	G4MYE0	G4MQQ0	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
MGG_08122	MGG_01759	G4MYE0	G4MVC9	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_08122	MGG_08646	G4MYE0	G4ML38	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_08122	MGG_09293	G4MYE0	G4MQP3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_08122	MGG_17683	G4MYE0	G4NIS8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_08646	MCM7	G4ML38	G4MQQ0	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
MGG_08646	MGG_01759	G4ML38	G4MVC9	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_08646	MGG_08122	G4ML38	G4MYE0	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_08646	MGG_09293	G4ML38	G4MQP3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MGG_08646	MGG_17683	G4ML38	G4NIS8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999