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PRT1 PRT1 HCR1 HCR1 MGG_05156 MGG_05156 NIP1 NIP1 INT6 INT6 MGG_10653 MGG_10653 TIF1 TIF1 MGG_05266 MGG_05266 MGG_03855 MGG_03855 MGG_12177 MGG_12177 MGG_00117 MGG_00117 MGG_00789 MGG_00789 MGG_00847 MGG_00847 MGG_11482 MGG_11482 MGG_06509 MGG_06509 MGG_13474 MGG_13474 MGG_05264 MGG_05264 MGG_13200 MGG_13200 MGG_06077 MGG_06077 MGG_06066 MGG_06066 MGG_05204 MGG_05204 MGG_16739 MGG_16739 MGG_04941 MGG_04941 MGG_04877 MGG_04877 MGG_08170 MGG_08170 MGG_12301 MGG_12301 MGG_01207 MGG_01207 MGG_08866 MGG_08866 TIF6 TIF6 MGG_01592 MGG_01592 MGG_01549 MGG_01549 MGG_04647 MGG_04647 MGG_11382 MGG_11382 MGG_05370 MGG_05370 TIF32 TIF32 MGG_01595 MGG_01595 TIF35 TIF35 DED1 DED1 MGG_00341 MGG_00341 TIF34 TIF34
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
Predicted Interactions
gene neighborhood
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PRT1Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (746 aa)
HCR1Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (273 aa)
MGG_05156Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (363 aa)
NIP1Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (865 aa)
INT6Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (446 aa)
MGG_10653Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (370 aa)
TIF1ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (396 aa)
MGG_05266Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (471 aa)
MGG_03855Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (236 aa)
MGG_12177Translation initiation factor eIF-2B subunit family protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (593 aa)
MGG_00117Transcription initiation factor IIB. (701 aa)
MGG_00789Eukaryotic translation initiation factor 2 beta subunit. (320 aa)
MGG_00847Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (705 aa)
MGG_11482Translation initiation factor IF-2. (1154 aa)
MGG_06509Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (310 aa)
MGG_13474Eukaryotic translation initiation factor eIF-1. (115 aa)
MGG_05264Translation initiation factor 4B. (563 aa)
MGG_13200Eukaryotic translation initiation factor 2 subunit alpha. (310 aa)
MGG_06077Translation initiation factor eIF-2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (339 aa)
MGG_06066Eukaryotic translation initiation factor 5B. (1062 aa)
MGG_05204Transcription initiation factor TFIID subunit 14. (228 aa)
MGG_16739Eukaryotic translation initiation factor 5A. (164 aa)
MGG_04941S1-like domain-containing protein. (187 aa)
MGG_04877Transcription initiation factor TFIID subunit 6. (512 aa)
MGG_08170Translation initiation factor eIF4E3; Belongs to the eukaryotic initiation factor 4E family. (368 aa)
MGG_12301Translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (271 aa)
MGG_01207Transcription initiation factor TFIID subunit 1. (1157 aa)
MGG_08866Eukaryotic translation initiation factor 5. (430 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (246 aa)
MGG_01592Eukaryotic translation initiation factor 2 subunit gamma. (513 aa)
MGG_01549DNA replication initiation factor Cdc45. (871 aa)
MGG_04647Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. (244 aa)
MGG_11382Translation initiation factor RLI1. (610 aa)
MGG_05370Transcription initiation factor IIB. (371 aa)
TIF32Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1073 aa)
MGG_01595Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (432 aa)
TIF35Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (303 aa)
DED1ATP-dependent RNA helicase DED1; ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity). Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. (671 aa)
MGG_00341Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (573 aa)
TIF34Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (341 aa)
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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