(31 nodes) Basal transcription factors network (Pyricularia oryzae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	TOA2	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with tbp mediates transcriptional activity (By similarity). (116 aa)
	MGG_05370	Transcription initiation factor IIB. (371 aa)
	MGG_06690	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (516 aa)
	MGG_06742	Uncharacterized protein. (784 aa)
	MGG_15176	Cyclin-H. (397 aa)
	MGG_06909	HTH TFE/IIEalpha-type domain-containing protein. (418 aa)
	MGG_04720	BTP domain-containing protein. (395 aa)
	MGG_04761	Uncharacterized protein. (394 aa)
	MGG_15089	Uncharacterized protein. (93 aa)
	MGG_15601	TATA-box-binding protein. (255 aa)
	MGG_11130	Uncharacterized protein. (712 aa)
	MGG_01207	Transcription initiation factor TFIID subunit 1. (1157 aa)
	MGG_01235	Uncharacterized protein. (407 aa)
	MGG_01265	BTP domain-containing protein. (222 aa)
	MGG_01266	TAFII55_N domain-containing protein. (536 aa)
	MGG_01310	Uncharacterized protein. (278 aa)
	MGG_09574	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (208 aa)
	MGG_13401	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (410 aa)
	MGG_09459	TAFII28 domain-containing protein. (420 aa)
	MGG_04877	Transcription initiation factor TFIID subunit 6. (512 aa)
	MGG_05204	Transcription initiation factor TFIID subunit 14. (228 aa)
	MGG_06509	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (310 aa)
	MGG_03637	TATA-binding protein associated factor Taf2. (1579 aa)
	MGG_06470	DNA repair helicase RAD25. (835 aa)
	MGG_03605	CDK-activating kinase assembly factor MAT1. (360 aa)
	MGG_03192	RNA polymerase II transcription factor B subunit 1. (653 aa)
	MGG_03132	DNA repair helicase rad15. (795 aa)
	MGG_00397	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (490 aa)
	MGG_00885	TFIID_20kDa domain-containing protein. (814 aa)
	MGG_03956	Uncharacterized protein. (164 aa)
	MGG_03877	RNA polymerase II transcription factor B subunit 4. (380 aa)

Your Current Organism:

Pyricularia oryzae

NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MGG_00397	MGG_00885	G4NCE6	G4NDQ9	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	TFIID_20kDa domain-containing protein.	0.863
MGG_00397	MGG_01207	G4NCE6	G4MX00	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Transcription initiation factor TFIID subunit 1.	0.833
MGG_00397	MGG_01235	G4NCE6	G4MXK1	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein.	0.974
MGG_00397	MGG_01266	G4NCE6	G4MY40	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	TAFII55_N domain-containing protein.	0.835
MGG_00397	MGG_01310	G4NCE6	G4MYK2	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein.	0.837
MGG_00397	MGG_03132	G4NCE6	G4NAV5	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	DNA repair helicase rad15.	0.999
MGG_00397	MGG_03192	G4NCE6	G4NAD4	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	RNA polymerase II transcription factor B subunit 1.	0.999
MGG_00397	MGG_03605	G4NCE6	G4N7C1	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	CDK-activating kinase assembly factor MAT1.	0.999
MGG_00397	MGG_03637	G4NCE6	G4N720	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	TATA-binding protein associated factor Taf2.	0.858
MGG_00397	MGG_03877	G4NCE6	G4NHC5	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	RNA polymerase II transcription factor B subunit 4.	0.999
MGG_00397	MGG_03956	G4NCE6	G4NH31	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein.	0.830
MGG_00397	MGG_04720	G4NCE6	G4MQX2	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	BTP domain-containing protein.	0.483
MGG_00397	MGG_04761	G4NCE6	G4MTS0	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein.	0.977
MGG_00397	MGG_04877	G4NCE6	G4N2P6	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Transcription initiation factor TFIID subunit 6.	0.860
MGG_00397	MGG_05204	G4NCE6	G4N531	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Transcription initiation factor TFIID subunit 14.	0.408
MGG_00397	MGG_05370	G4NCE6	G4MKW9	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Transcription initiation factor IIB.	0.985
MGG_00397	MGG_06470	G4NCE6	G4N765	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	DNA repair helicase RAD25.	0.999
MGG_00397	MGG_06509	G4NCE6	G4N6W7	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.997
MGG_00397	MGG_06690	G4NCE6	G4ML50	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.999
MGG_00397	MGG_06742	G4NCE6	G4MLL1	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	Uncharacterized protein.	0.833