STRINGSTRING
MSH3 MSH3 MGG_13023 MGG_13023 MGG_06731 MGG_06731 MGG_02459 MGG_02459 MGG_07121 MGG_07121 MGG_07124 MGG_07124 MGG_15760 MGG_15760 MGG_08071 MGG_08071 MGG_04389 MGG_04389 MGG_07526 MGG_07526 MGG_06370 MGG_06370 MGG_03284 MGG_03284 MGG_03204 MGG_03204 MGG_03202 MGG_03202 MGG_00685 MGG_00685 MGG_00630 MGG_00630 MGG_00518 MGG_00518 MGG_00879 MGG_00879 MGG_00841 MGG_00841 MGG_00704 MGG_00704 MGG_04010 MGG_04010 MGG_03854 MGG_03854 MGG_04127 MGG_04127
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MSH3DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] (1151 aa)
MGG_13023Replication factor C subunit 3. (404 aa)
MGG_06731Uncharacterized protein. (192 aa)
MGG_02459DNA polymerase delta small subunit. (497 aa)
MGG_07121DNA mismatch repair protein mutL. (690 aa)
MGG_07124Replication protein A 32 kDa subunit. (275 aa)
MGG_15760Uncharacterized protein. (1107 aa)
MGG_08071DNA polymerase. (1103 aa)
MGG_04389Replication factor C subunit 2. (384 aa)
MGG_07526Replication factor C subunit 4. (358 aa)
MGG_06370DNA ligase. (896 aa)
MGG_03284DNA mismatch repair protein. (947 aa)
MGG_03204Replication factor C subunit 1. (1084 aa)
MGG_03202Replication factor C subunit 5. (352 aa)
MGG_00685Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (610 aa)
MGG_00630ATP-dependent DNA helicase srs2. (998 aa)
MGG_00518Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
MGG_00879DNA mismatch repair protein msh-2; Component of the post-replicative DNA mismatch repair system (MMR). (924 aa)
MGG_00841Exonuclease 1. (780 aa)
MGG_00704DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1218 aa)
MGG_04010Uncharacterized protein. (113 aa)
MGG_03854DNA ligase. (859 aa)
MGG_04127Uncharacterized protein. (452 aa)
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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