STRINGSTRING
MDM34 MDM34 MDM10 MDM10 MDM12 MDM12 MMM1 MMM1 MGG_15156 MGG_15156 MGG_05651 MGG_05651 MGG_07312 MGG_07312 MGG_08913 MGG_08913 MGG_04943 MGG_04943 MGG_12948 MGG_12948 MGG_05996 MGG_05996 MGG_06075 MGG_06075 MGG_06572 MGG_06572 MGG_03696 MGG_03696 MGG_03684 MGG_03684 MGG_06482 MGG_06482 MGG_13498 MGG_13498 MGG_06361 MGG_06361 MGG_00446 MGG_00446 MGG_00883 MGG_00883 MGG_00812 MGG_00812 MGG_04325 MGG_04325 MGG_04083 MGG_04083 MGG_03926 MGG_03926 MGG_03918 MGG_03918 MGCH7_ch7g661 MGCH7_ch7g661 MGCH7_ch7g1034 MGCH7_ch7g1034 ATG8 ATG8 ATG11 ATG11 ATG1 ATG1 HOG1 HOG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (550 aa)
MDM10Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (443 aa)
MDM12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (550 aa)
MMM1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (410 aa)
MGG_15156Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2460 aa)
MGG_05651Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (273 aa)
MGG_07312Osmosensing histidine protein kinase SLN1. (1201 aa)
MGG_08913DNA polymerase gamma. (1147 aa)
MGG_04943Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (415 aa)
MGG_12948Uncharacterized protein. (210 aa)
MGG_05996Ubiquitin C-terminal hydrolase; Belongs to the peptidase C19 family. (1024 aa)
MGG_06075Mitochondrial fission 1 protein; Has a role in mitochondrial fission. (154 aa)
MGG_06572Phosphatidylinositol-4-phosphate 5-kinase its3 (PtdIns(4)P-5-kinase). (1057 aa)
MGG_03696CMGC/CK2 protein kinase; Belongs to the protein kinase superfamily. (341 aa)
MGG_03684Mitochondrial distribution and morphology protein 38. (552 aa)
MGG_06482STE/STE7 protein kinase. (527 aa)
MGG_13498HDAC_interact domain-containing protein. (1476 aa)
MGG_06361Dynamin-A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
MGG_00446Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (351 aa)
MGG_00883STE/STE11 protein kinase. (1528 aa)
MGG_00812Uncharacterized protein. (117 aa)
MGG_04325WSC domain-containing protein. (281 aa)
MGG_04083Small nuclear ribonucleoprotein Sm D3. (119 aa)
MGG_03926Cell division protease ftsH. (748 aa)
MGG_03918Protein phosphatase 1K. (696 aa)
MGCH7_ch7g661Response regulatory domain-containing protein. (833 aa)
MGCH7_ch7g1034STE/STE7 protein kinase. (685 aa)
ATG8Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved [...] (123 aa)
ATG11Autophagy-related protein 11; Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity). (1395 aa)
ATG1Serine/threonine-protein kinase ATG1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...] (982 aa)
HOG1Mitogen-activated protein kinase HOG1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (357 aa)
Your Current Organism:
Pyricularia oryzae
NCBI taxonomy Id: 242507
Other names: Magnaporthe grisea 70-15, P. oryzae 70-15, Pyricularia oryzae 70-15
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