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mfA4 | Immunoreactive 32 kDa antigen PG49; Tip subunit of the minor fimbriae. These filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome. They play an important role in invasion of periodontal tissues and are recognized as major virulence factors (Probable); Belongs to the bacteroidetes fimbrillin superfamily. FimA/Mfa1 family. (333 aa) | ||||
hagA | Hemagglutinin protein HagA; Agglutinates erythrocytes. (2105 aa) | ||||
lspA | Lipoprotein signal peptidase, putative; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (226 aa) | ||||
htrA | htrA protein; Similar to GB:D90452, GB:D90453, GB:M64110, GB:M83216, SP:Q05682, PID:180195, GB:D90452, GB:D90453, GB:M64110, GB:M83216, SP:Q05682, PID:180195, GB:D90452, GB:D90453, GB:M64110, GB:M83216, SP:Q05682, PID:180195, GB:D90452, GB:D90453, GB:M64110, GB:M83216, SP:Q05682, and PID:180195; identified by sequence similarity; putative. (498 aa) | ||||
prtRII | Arginine-specific cysteine proteinase; Thiol protease. Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA (By similarity). Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable). (736 aa) |