STRINGSTRING
RB10446 RB10446 cypX cypX RB11975 RB11975 RB1588 RB1588 hetI hetI pltG pltG RB2103 RB2103 acpP acpP RB386 RB386 RB6500 RB6500 aas aas acpP-2 acpP-2 RB7276 RB7276 acrA1 acrA1 RB9937 RB9937
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RB10446Beta keto-acyl synthase; Best DB hits: BLAST: ddbj:BAA89384.1; (AB025342) ORF10 [Moritella marina]; E=3e-37 pir:T30185; hypothetical protein 7 - Shewanella sp ----- gb:; E=3e-36 pir:T37057; probable multi-domain beta keto-acyl synthase -; E=8e-35 COG: DR1945; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=3e-17 Rv3391_1; COG0451 Nucleoside-diphosphate-sugar epimerases; E=2e-14 BH2492; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=2e-13 PFAM: PF00109; Beta-ketoacyl synthase, N-ter; E=7.7e-09 PF02801; Beta-ketoacyl synthase, C-ter; E=7.6e-61 PF00109; Beta-ketoacyl syntha [...] (2941 aa)
cypXProbable cytochrome P450 T9E850; PMID: 20411542 best DB hits: BLAST: pir:T06288; probable cytochrome P450 T9E8.50 - Arabidopsis thaliana; E=5e-14 ddbj:BAA31438.1; (AB010393) ALK6 [Yarrowia lipolytica]; E=3e-13 pir:C81286; probable cytochrome P450 Cj1411c [imported] -; E=5e-13 COG: Cj1411c; COG2124 Cytochrome P450; E=4e-14 PFAM: PF00067; Cytochrome P450; E=1e-20. (514 aa)
RB11975Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...] (2471 aa)
RB1588Similar to acyl carrier protein; PMID: 8759840 best DB hits: BLAST: gb:AAB68774.1; (U94886) hemolysin [Brachyspira hyodysenteriae]; E=4e-04 embl:CAC08813.1; (AJ279022) putative acyl carrier protein; E=0.053 pir:T11213; probable acyl carrier protein - Streptomyces glaucescens; E=0.067. (151 aa)
hetIProbable phosphopantetheinyltransferase; Best DB hits: BLAST: gb:AAF19809.1; AF188287_1 (AF188287) MtaA [Stigmatella aurantiaca]; E=5e-17 pir:T00851; hypothetical protein T20F6.9 - Arabidopsis thaliana; E=2e-11 pir:E55210; hetI protein - Anabaena sp. (strain PCC 7120) -----; E=2e-11 COG: slr0495; COG2091 Phosphopantetheinyl transferase; E=3e-12 PFAM: PF01648; 4'-phosphopantetheinyl transferase s; E=7.5e-15; Belongs to the P-Pant transferase superfamily. (280 aa)
pltGProbable thioesterase; PMID: 9512878 best DB hits: BLAST: pir:T17425; probable thioesterase (EC 3.1.2.-) pltG - Pseudomonas; E=1e-14 gb:AAC01736.1; (AF040570) thioesterase [Amycolatopsis; E=2e-14 gb:AAG52991.1; (AF040570) RifR [Amycolatopsis mediterranei]; E=2e-14 COG: PA2411; COG3208 Predicted thioesterase; E=5e-14 PFAM: PF00753; Metallo-beta-lactamase superfami; E=0.15 PF00975; Thioesterase domain; E=7.3e-32. (260 aa)
RB2103Acyl-CoA synthetase; PMID: 9634230 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-101 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=4e-96 gb:AAG02359.1; AF210249_18 (AF210249) peptide synthetase NRPS5-4-3; E=7e-93 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=4e-97 Rv3826; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-82 VNG1339C; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=9e-19 PFAM: PF00501; AMP-binding enzyme; E=1.7e-07 PF00550; Phosphopantetheine attachment sit; [...] (781 aa)
acpPAcyl carrier protein precursor; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (81 aa)
RB386Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...] (1204 aa)
RB6500Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...] (3665 aa)
aasAcyl-[ACP]--phospholipid O-acyltransferase; PMID: 8300626 best DB hits: BLAST: pir:A81368; probable 2-acylglycerophosphoethanolamine acyltransferase; E=2e-89 swissprot:P31119; AAS_ECOLI AAS BIFUNCTIONAL PROTEIN [INCLUDES:; E=5e-59 gb:AAG57948.1; AE005512_7 (AE005512); E=6e-59 COG: Cj0938c_3; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=6e-66 aas_2; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=6e-50 VNG1339C; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=2e-28 PFAM: PF01553; Acyltransferase; E=7.6e-22 PF00501; AMP-binding enzyme; E=2.4e-07. (766 aa)
acpP-2Probable acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (129 aa)
RB7276Peptide synthetase; PMID: 20392447 best DB hits: BLAST: embl:CAC01604.1; (AJ269505) peptide synthetase [Anabaena sp. 90]; E=4e-91 embl:CAC11137.1; (AJ250581) NikP1 protein [Streptomyces tendae]; E=9e-91 gb:AAF17281.1; (AF204805) NosD [Nostoc sp. GSV224]; E=4e-89 COG: PA2424_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=9e-85 BS_ppsC_1; COG1020 Non-ribosomal peptide synthetase modules and; E=5e-83 BS_dhbF; COG1020 Non-ribosomal peptide synthetase modules and related; E=2e-81 PFAM: PF00501; AMP-binding enzyme; E=2.2e-131 PF00550; Phosphopantetheine attachment; E=3.1e [...] (916 aa)
acrA1Probable acrA1 protein; Best DB hits: BLAST: pir:F70974; probable acrA1 protein - Mycobacterium tuberculosis; E=4e-15 gb:AAG31130.1; AF299336_7 (AF299336) MxcG [Stigmatella aurantiaca]; E=6e-12 pir:T37054; hypothetical protein SCJ21.05 - Streptomyces coelicolor; E=7e-10 COG: Rv3391_1; COG0451 Nucleoside-diphosphate-sugar epimerases; E=4e-16 PA4078_2; COG3320 Epimerase domains of multifunctional non-ribosomal; E=2e-04 PFAM: PF01073; 3-beta hydroxysteroid dehydro; E=0.7. (501 aa)
RB9937Best DB hits: BLAST: pir:H82133; conserved hypothetical protein VC1966 [imported] -; E=1e-23 pir:F81867; probable integral membrane protein NMA1715 [imported] -; E=4e-22 pir:B81074; transporter, probable NMB1515 [imported] - Neisseria; E=1e-21 COG: VC1966_1; COG0477 Permeases of the major facilitator superfamily; E=1e-22. (503 aa)
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.