STRINGSTRING
surE-2 surE-2 suhB suhB RB3245 RB3245 RB2717 RB2717 RB1828 RB1828 RB1412 RB1412 RB12002 RB12002 arsC arsC RB10818 RB10818 RB1066 RB1066 surE surE RB4512 RB4512 sps sps RB5200 RB5200 suhB-2 suhB-2 phoA phoA phoD phoD serB serB Pph1 Pph1 sixA sixA phoD-2 phoD-2 RB8835 RB8835 phoD-3 phoD-3 phoD-4 phoD-4 RB9769 RB9769 RB9821 RB9821
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
surE-2Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (266 aa)
suhBInositol-1-monophosphatase; PMID: 10747806 best DB hits: BLAST: gb:AAK02399.1; (AE006067) SuhB [Pasteurella multocida]; E=5e-35 ddbj:BAB06354.1; (AP001516) myo-inositol-1(or 4)-monophosphatase; E=2e-33 swissprot:P22783; SUHB_ECOLI EXTRAGENIC SUPPRESSOR PROTEIN SUHB; E=6e-33 COG: BH2635; COG0483 Archaeal fructose-1,6-bisphosphatase and related; E=2e-34 VC2722; COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS); E=4e-11 PFAM: PF00459; Inositol monophosphatase family; E=8.5e-66. (295 aa)
RB3245Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09. (335 aa)
RB2717Conserved hypothetical protein-putative dual specificity phosphatase MKP-5; PMID: 10391943 best DB hits: BLAST: gb:AAD15447.1; (AC006068) unknown protein [Arabidopsis thaliana]; E=8e-21 gb:AAF56179.1; (AE003744) CG10371 gene product [Drosophila; E=3e-17 ddbj:BAB09879.1; (AB013392) contains similarity to unknown; E=4e-16 COG: PH1732; COG2453 Predicted protein-tyrosine phosphatase; E=3e-10 PFAM: PF00782; Dual specificity phosphatase, cataly; E=1.3e-08. (185 aa)
RB1828Hypothetical protein-signal peptide and transmembrane prediction. (611 aa)
RB1412Inositol monophosphatase family protein; PMID: 8626508 best DB hits: BLAST: swissprot:P56160; YHEB_CHLVI HYPOTHETICAL 28.2 KD PROTEIN IN HEMB; E=5e-37 pir:B70646; probable monophosphatase - Mycobacterium tuberculosis; E=4e-34 embl:CAB94593.1; (AL359214) putative monophosphatase; E=2e-33 COG: Rv3137; COG0483 Archaeal fructose-1,6-bisphosphatase and related; E=4e-35 VC2722; COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS); E=2e-13 VC0745; COG0483 Archaeal fructose-1,6-bisphosphatase and related; E=3e-12 PFAM: PF00459; Inositol monophosphatase family; E=6.9e-53. (308 aa)
RB12002Conserved hypothetical protein; PMID: 8905231 best DB hits: BLAST: pir:F72334; conserved hypothetical protein - Thermotoga maritima; E=2e-16 pir:H75400; conserved hypothetical protein - Deinococcus radiodurans; E=6e-12 pir:S75046; hypothetical protein slr1718 - Synechocystis sp. (strain; E=3e-11 COG: TM0797; COG2045 Uncharacterized ACR; E=2e-17; Belongs to the ComB family. (268 aa)
arsCProbable arsenate reductase; PMID: 10567266 PMID: 9537360 PMID: 8003493 best DB hits: BLAST: pir:F75607; arsenate reductase - Deinococcus radiodurans (strain R1); E=1e-04 swissprot:P45947; ARSC_BACSU ARSENATE REDUCTASE (ARSENICAL PUMP; E=0.001 pir:B70360; arsenate reductase - Aquifex aeolicus -----gb:; E=0.014 COG: DRA0123; COG0394 Protein-tyrosine-phosphatase; E=1e-05. (216 aa)
RB10818PMID: 7798145 best DB hits: BLAST: swissprot:P39155; YWLE_BACSU PUTATIVE LOW MOLECULAR WEIGHT; E=1e-13 swissprot:Q45408; EPSP_BURSO PROBABLE LOW MOLECULAR WEIGHT; E=3e-10 ddbj:BAB07488.1; (AP001519) protein-tyrosine-phosphatase; E=1e-09 COG: BS_ywlE; COG0394 Protein-tyrosine-phosphatase; E=1e-14 VC1079; COG0009 Putative translation factor (SUA5); E=2e-06 BH2998; COG0394 Protein-tyrosine-phosphatase; E=8e-05 PFAM: PF01300; SUA5/yciO/yrdC family; E=0.14 PF01451; Low molecular weight phosphoty; E=2.2e-28; Belongs to the SUA5 family. (461 aa)
RB1066Hypothetical protein. (820 aa)
surEAcid phosphatase SurE; PMID: 8905231 best DB hits: BLAST: swissprot:P73440; YE59_SYNY3 HYPOTHETICAL 24.9 KD PROTEIN SLL1459; E=4e-31 swissprot:O83434; SURE_TREPA STATIONARY-PHASE SURVIVAL PROTEIN; E=3e-22 gb:AAD51394.1; AF117715_3 (AF117715) survival protein homolog; E=4e-20 COG: sll1459; COG0496 Survival protein, predicted acid phosphatase; E=4e-32 PFAM: PF01975; Survival protein SurE; E=9.8e-49. (289 aa)
RB4512Best DB hits: BLAST: pir:G75425; conserved hypothetical protein - Deinococcus radiodurans; E=5e-44 embl:CAA59823.1; (X85811) ORF N2219 [Saccharomyces cerevisiae]; E=4e-11 embl:CAA95970.1; (Z71370) ORF YNL094w [Saccharomyces cerevisiae]; E=4e-11. (407 aa)
spsSucrose-phosphate synthase 1; PMID: 1840396 PMID: 10411273 best DB hits: BLAST: pir:S75935; hypothetical protein - Synechocystis sp. (strain PCC; E=1e-155 pir:T04062; sucrose-phosphate synthase homolog F28M11.40 - Arabidopsis; E=6e-91 pir:T04103; sucrose-phosphate synthase (EC 2.4.1.14) 1 - rice; E=1e-87 COG: sll0045_1; COG0438 Predicted glycosyltransferases; E=1e-111 sll0045_2; COG0561 Predicted hydrolases of the HAD superfamily; E=8e-40 PH1844; COG0438 Predicted glycosyltransferases; E=2e-11 PFAM: PF00534; Glycosyl transferases group 1; E=2.6e-18 PF00702; haloacid dehalogenase-like h [...] (771 aa)
RB5200Alpha-amylase; PMID: 1747104 best DB hits: BLAST: ddbj:BAA11010.1; (D64130) alpha-amylase [Sulfolobus solfataricus]; E=4e-93 pir:JC5135; alpha-amylase (EC 3.2.1.1) - Sulfolobus solfataricus; E=4e-93 pir:S73087; alpha-amylase (EC 3.2.1.1) precursor - Sulfolobus; E=1e-89 COG: Rv1562c; COG0296 1,4-alpha-glucan branching enzyme; E=6e-72 BS_amyX; COG1523 Pullulanase and related glycosidases; E=1e-14 YEL011w; COG0296 1,4-alpha-glucan branching enzyme; E=1e-12 PFAM: PF00128; Alpha amylase, catalytic domain; E=2.4e-17; Belongs to the glycosyl hydrolase 13 family. (942 aa)
suhB-2Inositol-1-monophosphatase; PMID: 8002619 PMID: 10747806 best DB hits: BLAST: pir:F81092; extragenic suppressor protein SuhB NMB1347 [imported] -; E=3e-45 pir:B81848; inositol monophosphate family protein NMA1559 [imported]; E=1e-44 pir:C83169; extragenic suppressor protein SuhB PA3818 [imported] -; E=3e-42 COG: NMB1347; COG0483 Archaeal fructose-1,6-bisphosphatase and related; E=3e-46 PFAM: PF00459; Inositol monophosphatase family; E=1.4e-70. (275 aa)
phoAProbable alkaline phosphatase; PMID: 8454193 PMID: 3537962 PMID: 7022451 best DB hits: BLAST: swissprot:P35483; PPBH_PSEAE ALKALINE PHOSPHATASE H PRECURSOR; E=2e-11 pdb:1ANI; A Chain A, Alkaline Phosphatase (D153h, K328h) -----; E=2e-11 pdb:2ANH; A Chain A, Alkaline Phosphatase (D153h) -----pdb:; E=3e-11 COG: PA3296; COG1785 Alkaline phosphatase; E=2e-12 PFAM: PF00245; Alkaline phosphatase; E=2.2e-09. (628 aa)
phoDProbable alkaline phosphatase D; PMID: 8760916 PMID: 25878 best DB hits: BLAST: swissprot:P42251; PPBD_BACSU ALKALINE PHOSPHATASE D PRECURSOR; E=6e-09 pir:F83157; hypothetical protein PA3910 [imported] - Pseudomonas; E=5e-08 pir:T35097; probable secreted alkaline phosphatase - Streptomyces; E=2e-06. (471 aa)
serBProbable phosphoserine phosphatase; PMID: 2997734 best DB hits: BLAST: pir:C83025; probable phosphoserine phosphatase PA4960 [imported] -; E=1e-108 pir:E70860; probable serB2 protein - Mycobacterium tuberculosis; E=1e-60 pir:T36772; probable phosphoserine phosphatase - Streptomyces; E=1e-57 COG: PA4960_2; COG0560 Phosphoserine phosphatase; E=5e-70 PA4960_1; COG2716 ACT domain-containing protein; E=3e-31 jhp0597; COG0560 Phosphoserine phosphatase; E=6e-26 PFAM: PF01842; ACT domain; E=0.052 PF00702; haloacid dehalogenase-like hy; E=3.6e-26. (485 aa)
Pph1Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09. (485 aa)
sixAConserved hypothetical protein-putative phosphohistidine phosphatase; Best DB hits: BLAST: pir:T36773; hypothetical protein SCI28.03c - Streptomyces coelicolor; E=2e-12 pir:T49094; hypothetical protein F4F15.260 - Arabidopsis thaliana; E=5e-12 swissprot:Q11043; YC76_MYCTU HYPOTHETICAL 16.5 KDA PROTEIN RV1276C; E=3e-08 COG: Rv1276c; COG2062 Phosphohistidine phosphatase SixA; E=3e-09 slr1124; COG0406 Phosphoglycerate mutase/fructose-2,6-bisphosphatase; E=0.001 Cj1002c; COG2062 Phosphohistidine phosphatase SixA; E=0.002 PFAM: PF00300; Phosphoglycerate mutase family; E=0.013. (201 aa)
phoD-2Probable alkaline phosphatase D [Precursor]; PMID: 8760916 best DB hits: BLAST: embl:CAC18240.1; (AL451018) conserved hypothetical protein; E=2e-12 ddbj:BAB10478.1; (AB016888) gene_id:MDH9.6~similar to unknown; E=2e-12 embl:CAB92825.1; (AL356892) hypothetical protein [Streptomyces; E=6e-05. (470 aa)
RB8835Probable secreted alkaline phosphatase (fragment); Best DB hits: BLAST: embl:CAB99170.1; (AL390188) putative secreted alkaline; E=0.003 embl:CAC18240.1; (AL451018) conserved hypothetical protein; E=0.004 ddbj:BAA06483.1; (D30808) unknown [Bacillus subtilis]; E=0.10 PFAM: PF02908; Purple acid phosphatase, N-term; E=0.89 PF00041; Fibronectin type III domain; E=0.42. (620 aa)
phoD-3Alkaline phosphatase D [Precursor]; PMID: 8760916 PMID: 25878 best DB hits: BLAST: swissprot:P42251; PPBD_BACSU ALKALINE PHOSPHATASE D PRECURSOR; E=1e-124 ddbj:BAA06483.1; (D30808) unknown [Bacillus subtilis]; E=1e-110 pir:T50595; probable alkaline phosphatase [imported] - Streptomyces; E=1e-103. (527 aa)
phoD-4Probable alkaline phosphatase D [Precursor]; PMID: 8760916 best DB hits: BLAST: pir:F83157; hypothetical protein PA3910 [imported] - Pseudomonas; E=6e-05 ddbj:BAA06483.1; (D30808) unknown [Bacillus subtilis]; E=1e-04 swissprot:P42251; PPBD_BACSU ALKALINE PHOSPHATASE D PRECURSOR; E=1e-04. (685 aa)
RB9769Best DB hits: BLAST: pir:F83457; hypothetical protein PA1506 [imported] - Pseudomonas; E=9e-13 COG: PA1506; COG0394 Protein-tyrosine-phosphatase; E=9e-14 PFAM: PF01451; Low molecular weight phosphotyrosine; E=0.00019. (121 aa)
RB9821Best DB hits: BLAST: pir:B82065; conserved hypothetical protein VC2524 [imported] -; E=9e-28 embl:CAC12689.1; (AJ272115) hypothetical protein [Thauera; E=6e-26 pir:B83087; conserved hypothetical protein PA4458 [imported] -; E=7e-26 COG: VC2524; COG1778 Uncharacterized proteins of HAD superfamily,; E=8e-29 APE0766; COG0561 Predicted hydrolases of the HAD superfamily; E=6e-05. (180 aa)
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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