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RB614 RB614 RB983 RB983 RB9110 RB9110 RB8639 RB8639 RB8505 RB8505 flhF flhF yidC yidC RB8085 RB8085 RB787 RB787 RB7541 RB7541 RB7538 RB7538 RB749 RB749 RB7012 RB7012 RB6486 RB6486 RB6400 RB6400 RB638 RB638 RB6207 RB6207 RB5557 RB5557 RB5429 RB5429 RB5380 RB5380 RB5272 RB5272 RB4931 RB4931 RB4667 RB4667 RB4593 RB4593 ftsY ftsY RB3003 RB3003 RB2960 RB2960 RB2837 RB2837 lolD lolD RB1451 RB1451 yfgL yfgL RB12942 RB12942 ffh ffh adh adh RB12303 RB12303 RB12068 RB12068 RB12056 RB12056 RB11660 RB11660 RB11463 RB11463 RB11142 RB11142 RB10916 RB10916 RB10911 RB10911 RB10839 RB10839 RB10716 RB10716 RB10706 RB10706 RB107 RB107 RB10124 RB10124 RB10035 RB10035
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RB614PMID: 7601151 PMID: 8654419 best DB hits: BLAST: pir:S52317; quinohemoprotein ethanol dehydrogenase (EC 1.1.99.-); E=0.006 gb:AAF86335.1; (AF277373) terahydrofurfuryl alcohol dehydrogenase; E=0.36 pir:A82284; conserved hypothetical protein VC0762 [imported] -; E=0.76 PFAM: PF01011; PQQ enzyme repeat; E=0.29. (399 aa)
RB983Probable serine/threonine protein kinase; PMID: 8063104 best DB hits: BLAST: swissprot:P54741; AFSK_STRCO SERINETHREONINE PROTEIN KINASE AFSK; E=0.001 embl:CAB88430.1; (AL353815) serinethreonine protein kinase; E=0.001 pir:H69064; serinethreonine protein kinase related protein -; E=0.001 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=1e-04 PFAM: PF01011; PQQ enzyme repeat; E=0.77. (425 aa)
RB9110Best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=0.037 embl:CAB57415.1; (AL121746) hypothetical protein SCF73.10c; E=0.075 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=0.003 PFAM: PF01011; PQQ enzyme repeat; E=0.25. (583 aa)
RB8639Conserved hypothetical protein; Best DB hits: BLAST: gb:AAG20856.1; (AE005154) Vng6189h [Halobacterium sp. NRC-1]; E=5e-05 pir:H69064; serinethreonine protein kinase related protein -; E=0.005 pir:C82804; conserved hypothetical protein XF0464 [imported] -; E=0.053 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=5e-04 PFAM: PF01011; PQQ enzyme repeat; E=0.27. (459 aa)
RB8505Best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=4e-04 swissprot:P77774; YFGL_ECOLI HYPOTHETICAL 41.9 KD PROTEIN IN; E=0.004 gb:AAG20856.1; (AE005154) Vng6189h [Halobacterium sp. NRC-1]; E=0.007 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=4e-05 PFAM: PF01011; PQQ enzyme repeat; E=0.03. (439 aa)
flhFPMID: 1447978 best DB hits: BLAST: pir:B72319; flagellar biosynthesis protein FlhF - Thermotoga; E=9e-32 ddbj:BAB06156.1; (AP001515) flagella-associated protein [Bacillus; E=3e-22 swissprot:Q01960; FLHF_BACSU FLAGELLAR BIOSYNTHESIS PROTEIN FLHF; E=2e-21 COG: TM0907; COG1419 Flagellar GTP-binding protein; E=8e-33 AF0622; COG0541 Signal recognition particle GTPase; E=3e-09 PFAM: PF00005; ABC transporter; E=0.018 PF00931; NB-ARC domain; E=0.2 PF00004; ATPase family associated with va; E=0.13. (464 aa)
yidC60 kDa inner-membrane protein homolog-putative part of a protein secretion system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity). (827 aa)
RB8085Conserved hypothetical protein-putative PQQ-repeat containing protein; PMID: 11705915 best DB hits: BLAST: gb:AAG31169.1; (AF314961) unknown [Salmonella typhimurium]; E=0.70 PFAM: PF01011; PQQ enzyme repeat; E=0.017. (495 aa)
RB787Similar to transposase; PMID: 11325940 best DB hits: BLAST: ddbj:BAA89624.1; (AB036665) similar to transposase of Tn5; E=0.043 embl:CAA23888.1; (V00615) open reading frame [Escherichia coli]; E=0.17 embl:CAA23891.1; (V00617) open reading frame [Escherichia coli]; E=0.17 PFAM: PF01609; Transposase (IS4 family); E=0.079. (403 aa)
RB7541PMID: 98037514 best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=0.16. (692 aa)
RB7538Conserved hypothetical protein; PMID: 20406833 best DB hits: BLAST: pir:A82284; conserved hypothetical protein VC0762 [imported] -; E=0.029 pir:T29127; hypothetical protein SC1F2.18 - Streptomyces coelicolor; E=0.18 pir:H69064; serinethreonine protein kinase related protein -; E=0.49 COG: VC0762; COG1520 Uncharacterized proteins of WD40-like repeat family; E=0.003 PFAM: PF01011; PQQ enzyme repeat; E=0.054. (667 aa)
RB749PMID: 9371463 best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=5e-05 pir:JC4881; polyvinyl-alcohol dehydrogenase (acceptor) (EC; E=0.017 gb:AAB89850.1; (AE001008) conserved hypothetical protein; E=0.076 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=4e-06 PFAM: PF01011; PQQ enzyme repeat; E=0.1 PF00993; Class II histocompatibility ant; E=0.47 PF01011; PQQ enzyme repeat; E=0.00012. (537 aa)
RB7012Conserved hypothetical protein; PMID: 10731132 best DB hits: BLAST: gb:AAF54635.1; (AE003691) CG5270 gene product [Drosophila; E=0.17 PFAM: PF02058; Guanylin precursor; E=0.1. (389 aa)
RB6486PMID: 9371463 best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=3e-13 pir:C75264; probable serinethreonine protein kinase - Deinococcus; E=1e-08 swissprot:P42111; YXAL_BACSU HYPOTHETICAL 38.5 KDA PROTEIN IN; E=5e-07 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=3e-14 DR2518_2; COG1520 Uncharacterized proteins of WD40-like repeat; E=5e-09 BS_yxaL; COG1520 Uncharacterized proteins of WD40-like repeat family; E=4e-08 PFAM: PF01011; PQQ enzyme repeat; E=0.0066. (455 aa)
RB6400Hypothetical protein-transmembrane prediction; Best DB hits: PFAM: PF00397; WW domain; E=0.54. (425 aa)
RB638Similar to serine/threonine protein kinase; PMID: 8063104 best DB hits: BLAST: swissprot:P54741; AFSK_STRCO SERINETHREONINE PROTEIN KINASE AFSK; E=0.077 embl:CAB88430.1; (AL353815) serinethreonine protein kinase; E=0.077 pir:A82284; conserved hypothetical protein VC0762 [imported] -; E=0.32 PFAM: PF01011; PQQ enzyme repeat; E=0.39. (436 aa)
RB6207Conserved hypothetical protein; PMID: 9389475 best DB hits: BLAST: gb:AAB89850.1; (AE001008) conserved hypothetical protein; E=2e-05 swissprot:P54741; AFSK_STRCO SERINETHREONINE PROTEIN KINASE AFSK; E=0.064 embl:CAB88430.1; (AL353815) serinethreonine protein kinase; E=0.064 COG: AF1399; COG1520 Uncharacterized proteins of WD40-like repeat family; E=2e-06 PFAM: PF01011; PQQ enzyme repeat; E=0.47 PF02316; Mu DNA-binding domain; E=0.84. (436 aa)
RB5557Similar to dehydrogenase; PMID: 2549854 best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=0.002 pir:T29127; hypothetical protein SC1F2.18 - Streptomyces coelicolor; E=0.015 gb:AAG57622.1; AE005480_9 (AE005480) putative dehydrogenase; E=0.63 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=2e-04 PFAM: PF01011; PQQ enzyme repeat; E=0.49. (414 aa)
RB5429Conserved hypothetical protein; PMID: 10360571 best DB hits: BLAST: pir:D72313; hypothetical protein TM0945 - Thermotoga maritima; E=2e-46 pir:D82689; conserved hypothetical protein XF1384 [imported] -; E=4e-22 gb:AAF04097.1; AF188291_3 (AF188291) PqaA [Salmonella typhi]; E=2e-17. (460 aa)
RB5380PMID: 8063104 best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=9e-06 swissprot:P54741; AFSK_STRCO SERINETHREONINE PROTEIN KINASE AFSK; E=0.007 swissprot:P54742; AFSK_STRGR SERINETHREONINE PROTEIN KINASE AFSK; E=0.007 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=8e-07 PFAM: PF01011; PQQ enzyme repeat; E=0.0098. (473 aa)
RB5272Conserved hypothetical protein; PMID: 9389475 best DB hits: BLAST: gb:AAB89850.1; (AE001008) conserved hypothetical protein; E=0.006 gb:AAG09249.1; AF176640_2 (AF176640) alcohol dehydrogenase; E=0.20 gb:AAD56237.2; AF184915_1 (AF184915) methanol dehydrogenase large; E=0.22 COG: AF1399; COG1520 Uncharacterized proteins of WD40-like repeat family; E=5e-04 PFAM: PF01011; PQQ enzyme repeat; E=0.022. (457 aa)
RB4931Hypothetical protein-transmembrane region and signal peptide prediction; PMID: 12093901. (217 aa)
RB4667Conserved hypothetical protein; Best DB hits: BLAST: gb:AAB89850.1; (AE001008) conserved hypothetical protein; E=0.24. (451 aa)
RB4593Hypothetical protein-transmembrane regio and signal peptide prediction. (404 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (337 aa)
RB3003PMID: 9371463 best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=0.005 gb:AAG31643.1; AF309488_1 (AF309488) methanol dehydrogenase large; E=0.009 pir:F72237; conserved hypothetical protein - Thermotoga maritima; E=0.29 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=5e-04 PFAM: PF01011; PQQ enzyme repeat; E=0.00081. (507 aa)
RB2960Hypothetical protein-transmembrane prediction; PMID: 9389475 best DB hits: PFAM: PF01011; PQQ enzyme repeat; E=0.12. (489 aa)
RB2837Hypothetical protein-putative transmembrane protein; Best DB hits: PFAM: PF01011; PQQ enzyme repeat; E=0.14. (614 aa)
lolDLipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (229 aa)
RB1451Similar to serine/threonine protein kinase related protein; PMID: 9371463 PMID: 11677609 best DB hits: BLAST: gb:AAG31169.1; (AF314961) unknown [Salmonella typhimurium]; E=0.043 gb:AAB89850.1; (AE001008) conserved hypothetical protein; E=0.049 pir:A82284; conserved hypothetical protein VC0762 [imported] -; E=0.13 COG: AF1399; COG1520 Uncharacterized proteins of WD40-like repeat family; E=0.005 PFAM: PF01011; PQQ enzyme repeat; E=5.4e-05. (464 aa)
yfgLConserved hypothetical protein; Best DB hits: BLAST: swissprot:P77774; YFGL_ECOLI HYPOTHETICAL 41.9 KD PROTEIN IN; E=0.006 gb:AAG57622.1; AE005480_9 (AE005480) putative dehydrogenase; E=0.007 gb:AAG31169.1; (AF314961) unknown [Salmonella typhimurium]; E=0.056 COG: yfgL; COG1520 Uncharacterized proteins of WD40-like repeat family; E=6e-04. (449 aa)
RB12942Hypothetical protein-transmembrane prediction. (500 aa)
ffhSignal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. (491 aa)
adhProbable alcohol dehydrogenase [acceptor]; PMID: 2001402 best DB hits: BLAST: swissprot:P28036; DHET_ACEPO ALCOHOL DEHYDROGENASE [ACCEPTOR]; E=0.003 gb:AAB89850.1; (AE001008) conserved hypothetical protein; E=0.003 swissprot:Q44002; DHET_ACEEU ALCOHOL DEHYDROGENASE [ACCEPTOR]; E=0.004 COG: AF1399; COG1520 Uncharacterized proteins of WD40-like repeat family; E=3e-04 PFAM: PF01011; PQQ enzyme repeat; E=5.5e-05. (420 aa)
RB12303Best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=3e-04 gb:AAG20856.1; (AE005154) Vng6189h [Halobacterium sp. NRC-1]; E=0.007 gb:AAF16758.1; AC010155_11 (AC010155) F3M18.23 [Arabidopsis; E=0.014 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=3e-05 PFAM: PF01011; PQQ enzyme repeat; E=0.0074. (625 aa)
RB12068Probable serine/threonine protein kinase afsK; PMID: 8063104 PMID: 8635757 PMID: 12000953 best DB hits: BLAST: gb:AAB89850.1; (AE001008) conserved hypothetical protein; E=2e-06 swissprot:P54741; AFSK_STRCO SERINETHREONINE PROTEIN KINASE AFSK; E=1e-05 embl:CAB88430.1; (AL353815) serinethreonine protein kinase; E=1e-05 COG: AF1399; COG1520 Uncharacterized proteins of WD40-like repeat family; E=1e-07 PFAM: PF01011; PQQ enzyme repeat; E=0.00048. (553 aa)
RB12056Conserved hypothetical protein containing TPR domain; PMID: 10192388 best DB hits: BLAST: pir:T39943; hypothetical protein SPBC23E6.09 - fission yeast; E=2e-04 pir:C72048; tpr repeats-ct683 hypothetical protein - Chlamydophila; E=0.006 swissprot:P42810; YAG7_PSEAE HYPOTHETICAL PROTEIN PA4667 -----; E=0.24 COG: CPn0693; COG0457 TPR-repeat-containing proteins; E=6e-04 PFAM: PF00515; TPR Domain; E=0.0018 PF00903; Glyoxalase/Bleomycin resistance; E=0.85 PF00515; TPR Domain; E=0.52. (1113 aa)
RB11660PMID: 9371463 best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=0.001 pir:T26310; hypothetical protein W09D6.1 - Caenorhabditis elegans; E=0.64 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=1e-04 PFAM: PF01011; PQQ enzyme repeat; E=0.047. (748 aa)
RB11463Hypothetical protein; Best DB hits: PFAM: PF01011; PQQ enzyme repeat; E=0.39. (503 aa)
RB11142Hypothetical protein-signal peptide prediction; Best DB hits: PFAM: PF01011; PQQ enzyme repeat; E=0.34. (481 aa)
RB10916Outer membrane protein homolog; PMID: 9403685 best DB hits: BLAST: pir:B70199; outer membrane protein homolog - Lyme disease spirochete; E=6e-17 pir:C70412; outer membrane protein - Aquifex aeolicus -----gb:; E=3e-16 gb:AAA96788.1; (U51683) OMP1 precursor [Brucella abortus]; E=2e-15 COG: BB0795; COG0729 Predicted outer membrane protein; E=6e-18 PFAM: PF01103; Bacterial surface antigen; E=1.3e-16. (503 aa)
RB10911Probable outer membrane protein; Best DB hits: BLAST: gb:AAA96788.1; (U51683) OMP1 precursor [Brucella abortus]; E=1e-14 pir:C70412; outer membrane protein - Aquifex aeolicus ----- gb:; E=5e-12 pir:H83190; probable outer membrane protein PA3648 [imported] -; E=1e-10 COG: aq_1300; COG0729 Predicted outer membrane protein; E=5e-13 PFAM: PF01103; Bacterial surface antigen; E=0.00093. (557 aa)
RB10839Best DB hits: BLAST: pir:T36293; probable serinethreonine protein kinase - Streptomyces; E=0.15 gb:AAG20933.1; (AE005160) Vng6297c [Halobacterium sp. NRC-1]; E=0.24 pir:C82804; conserved hypothetical protein XF0464 [imported] -; E=0.56 PFAM: PF01011; PQQ enzyme repeat; E=0.045. (515 aa)
RB10716Conserved hypothetical protein-putative PQQ-dependent dehydrogenase; PMID: 11932238 best DB hits: BLAST: pir:C82804; conserved hypothetical protein XF0464 [imported] -; E=0.10 swissprot:Q9Z4J7; EXAA_PSEAE QUINOPROTEIN ETHANOL DEHYDROGENASE; E=0.29 pdb:1FLG; A Chain A, Crystal Structure Of The Quinoprotein Ethanol; E=0.29 COG: XF0464; COG1520 Uncharacterized proteins of WD40-like repeat family; E=0.009 PFAM: PF01011; PQQ enzyme repeat; E=0.0088. (456 aa)
RB10706Similar to serine/threonine protein kinase related protein-putative PQQ-dependent oxidoreductase; Best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=0.045 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=0.004 PFAM: PF01011; PQQ enzyme repeat; E=0.009. (1129 aa)
RB107Conserved hypothetical protein; PMID: 8921874 best DB hits: BLAST: pir:A58519; hypothetical 345 protein - Streptomyces coelicolor; E=0.14 pir:H69064; serinethreonine protein kinase related protein -; E=0.20 gb:AAG31169.1; (AF314961) unknown [Salmonella typhimurium]; E=0.64 PFAM: PF01011; PQQ enzyme repeat; E=0.2. (459 aa)
RB10124Best DB hits: BLAST: pir:A82580; polyvinylalcohol dehydrogenase XF2259 [imported] -; E=0.003 pir:H69064; serinethreonine protein kinase related protein -; E=0.013 pir:C83171; conserved hypothetical protein PA3800 [imported] -; E=0.14 COG: XF2259; COG1520 Uncharacterized proteins of WD40-like repeat family; E=3e-04 PFAM: PF01011; PQQ enzyme repeat; E=0.0033. (482 aa)
RB10035Conserved hypothetical protein-putative membrane bound PQQ-employing oxidoreductase; Best DB hits: BLAST: gb:AAG31169.1; (AF314961) unknown [Salmonella typhimurium]; E=0.23 pir:C82804; conserved hypothetical protein XF0464 [imported] -; E=0.79 PFAM: PF01011; PQQ enzyme repeat; E=0.016. (584 aa)
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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