STRINGSTRING
leuB leuB leuB-2 leuB-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (375 aa)
leuB-23-isopropylmalate dehydrogenase; PMID: 3110742 best DB hits: BLAST: pir:D75045; 3-isopropylmalate dehydrogenase (leub) PAB2424 -; E=2e-52 swissprot:O66607; LEU3_AQUAE 3-ISOPROPYLMALATE DEHYDROGENASE; E=6e-51 swissprot:Q9WZ26; LEU3_THEMA 3-ISOPROPYLMALATE DEHYDROGENASE; E=2e-49 COG: PAB2424; COG0473 Isocitrate/isopropylmalate dehydrogenase; E=2e-53 PFAM: PF00180; Isocitrate and isopropylmalate dehyd; E=6.3e-108 PF02376; CUT domain; E=0.32. (364 aa)
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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