STRINGSTRING
RB3686 RB3686 gcd gcd fdh fdh yjgB yjgB RB11975 RB11975 RB11985 RB11985 yhdH yhdH fdh-2 fdh-2 RB3488 RB3488 yjjN yjjN RB4399 RB4399 RB5320 RB5320 adh-2 adh-2 adh-3 adh-3 RB6500 RB6500 RB9584 RB9584
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RB3686Putative zinc-binding oxidoreductase; PMID: 8843436 best DB hits: BLAST: embl:CAC14345.1; (AL445945) putative zinc-binding oxidoreductase; E=2e-32 pir:C70418; probable alcohol dehydrogenase (EC 1.1.1.-) - Aquifex; E=4e-28 embl:CAB70647.1; (AL137242) putative zinc-binding oxidoreductase; E=2e-27 COG: aq_1362; COG0604 NADPH:quinone reductase and related Zn-dependent; E=3e-29 PFAM: PF00696; Amino acid kinase family; E=0.7 PF00107; Zinc-binding dehydrogenases; E=2.2e-72. (327 aa)
gcdGlucose dehydrogenase Gcd; PMID: 8436115 PMID: 2803257 best DB hits: BLAST: gb:AAG18991.1; (AE004999) glucose dehydrogenase; Gcd; E=2e-27 pir:T44937; glucose 1-dehydrogenase (EC 1.1.1.47) [imported] -; E=1e-25 pir:S29788; glucose 1-dehydrogenase (EC 1.1.1.47) - Thermoplasma; E=3e-13 COG: VNG0446G; COG1063 Threonine dehydrogenase and related Zn-dependent; E=2e-28 YDL168w; COG1062 Zn-dependent alcohol dehydrogenases, class III; E=0.003 XF1727; COG1063 Threonine dehydrogenase and related Zn-dependent; E=0.005 PFAM: PF00107; Zinc-binding dehydrogenases; E=3.1e-22. (371 aa)
fdhGlutathione-dependent formaldehyde dehydrogenase; PMID: 7926692 best DB hits: BLAST: swissprot:P47734; FADH_METMR GLUTATHIONE-DEPENDENT FORMALDEHYDE; E=1e-160 pir:A75593; alcohol dehydrogenase, zinc-containing - Deinococcus; E=1e-113 pir:B83373; probable alcohol dehydrogenase (Zn-dependent) PA2188; E=7e-84 COG: DRA0005; COG1063 Threonine dehydrogenase and related Zn-dependent; E=1e-114 sll0990; COG1062 Zn-dependent alcohol dehydrogenases, class III; E=7e-20 PFAM: PF00107; Zinc-binding dehydrogenases; E=3e-74. (389 aa)
yjgBHypothetical zinc-type alcohol dehydrogenase-like protein yjgB; PMID: 87304248 PMID: 92277668 best DB hits: BLAST: pir:S76928; probable aryl alcohol dehydrogenase (EC 1.1.1.-) -; E=1e-94 pir:S56495; probable aryl alcohol dehydrogenase (EC 1.1.1.-) yjgB -; E=6e-71 swissprot:P27250; YJGB_ECOLI HYPOTHETICAL ZINC-TYPE ALCOHOL; E=6e-71 COG: slr1192; COG1064 Zn-dependent alcohol dehydrogenases; E=9e-96 PFAM: PF00899; ThiF family; E=0.48 PF02826; D-isomer specific 2-hydroxyacid; E=0.48 PF00107; Zinc-binding dehydrogenases; E=5.9e-85. (336 aa)
RB11975Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...] (2471 aa)
RB11985Quinone oxidoreductase; PMID: 11058132 PMID: 7602590 PMID: 1420281 best DB hits: BLAST: ddbj:BAB04654.1; (AP001510) quinone oxidoreductase [Bacillus; E=2e-43 embl:CAB65629.1; (AL136149) putative oxidoreductase; E=1e-31 swissprot:P11415; QOR_CAVPO QUINONE OXIDOREDUCTASE (NADPH:QUINONE; E=3e-31 COG: BH0935; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-44 PA5427; COG1064 Zn-dependent alcohol dehydrogenases; E=6e-15 BH0738; COG0604 NADPH:quinone reductase and related Zn-dependent; E=5e-14 PFAM: PF00106; short chain dehydrogenase; E=0.46 PF00107; Zinc-binding dehydrogenase [...] (335 aa)
yhdHPutative zinc-binding alcohol dehydrogenase; Best DB hits: BLAST: swissprot:P26646; YHDH_ECOLI PROTEIN YHDH ----- pir: JS0688; E=4e-86 gb:AAG58380.1; AE005553_2 (AE005553) putative dehydrogenase; E=5e-86 pir:D82374; zinc-binding alcohol dehydrogenase VC0026 [imported] -; E=1e-76 COG: yhdH; COG0604 NADPH:quinone reductase and related Zn-dependent; E=4e-87 BH0538; COG1064 Zn-dependent alcohol dehydrogenases; E=0.001 PA0863; COG0604 NADPH:quinone reductase and related Zn-dependent; E=0.003 PFAM: PF00107; Zinc-binding dehydrogenases; E=2.3e-38. (326 aa)
fdh-2PMID: 8169197 best DB hits: BLAST: pir:F70090; probable formaldehyde dehydrogenase (EC 1.2.1.46) yycR -; E=1e-151 swissprot:P46154; FADH_PSEPU GLUTATHIONE-INDEPENDENT FORMALDEHYDE; E=1e-140 pir:E82969; glutathione-independent formaldehyde dehydrogenase; E=1e-138 COG: BS_yycR; COG1063 Threonine dehydrogenase and related Zn-dependent; E=1e-152 PFAM: PF01262; Alanine dehydrogenase/pyridine nucl; E=0.17 PF00107; Zinc-binding dehydrogenases; E=3.1e-48. (402 aa)
RB3488Sorbitol dehydrogenase; PMID: 1460002 PMID: 9384377 best DB hits: BLAST: swissprot:Q06004; DHSO_BACSU SORBITOL DEHYDROGENASE (L-IDITOL; E=1e-32 pir:G72376; alcohol dehydrogenase, zinc-containing - Thermotoga; E=2e-27 pir:H71110; probable dehydrogenase - Pyrococcus horikoshii -----; E=9e-25 COG: BS_gutB; COG1063 Threonine dehydrogenase and related Zn-dependent; E=1e-33 PFAM: PF00107; Zinc-binding dehydrogenases; E=2.2e-50. (414 aa)
yjjNZinc-type alcohol dehydrogenase; PMID: 3622514 PMID: 1593644 best DB hits: BLAST: swissprot:P39400; YJJN_ECOLI HYPOTHETICAL ZINC-TYPE ALCOHOL; E=1e-51 gb:AAG59541.1; AE005667_5 (AE005667) putative oxidoreductase; E=9e-51 pir:F69852; L-iditol 2-dehydrogenase (EC 1.1.1.14) homolog yjmD -; E=1e-38 COG: yjjN; COG1063 Threonine dehydrogenase and related Zn-dependent; E=1e-52 PFAM: PF01494; FAD binding domain; E=0.28 PF00070; Pyridine nucleotide-disulphide; E=0.0008 PF00107; Zinc-binding dehydrogenases; E=1.3e-68. (342 aa)
RB4399Quinone oxidoreductase; PMID: 7602590 best DB hits: BLAST: embl:CAB59716.1; (AL132707) putative zinc-binding oxidoreductase; E=3e-31 pir:T10203; hypothetical protein F25G13.100 - Arabidopsis thaliana; E=2e-28 embl:CAC14345.1; (AL445945) putative zinc-binding oxidoreductase; E=1e-26 COG: VC0552; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-26 PFAM: PF00107; Zinc-binding dehydrogenases; E=5.2e-48. (328 aa)
RB5320Probable zinc-type alcohol dehydrogenase; PMID: 3622514 best DB hits: BLAST: ddbj:BAA75341.1; (AB011837) sorbitol dehydrogenase [Bacillus; E=8e-44 swissprot:P77539; YDJL_ECOLI HYPOTHETICAL ZINC-TYPE ALCOHOL; E=7e-35 gb:AAG56765.1; AE005400_10 (AE005400) putative oxidoreductase; E=9e-35 COG: BH0189; COG1063 Threonine dehydrogenase and related Zn-dependent; E=7e-45 PFAM: PF00107; Zinc-binding dehydrogenases; E=6.5e-60. (396 aa)
adh-2PMID: 4578954 best DB hits: BLAST: pir:G72376; alcohol dehydrogenase, zinc-containing - Thermotoga; E=7e-23 gb:AAF17283.1; (AF204805) NosE [Nostoc sp. GSV224]; E=9e-19 ddbj:BAB10455.1; (AB005234) alcohol dehydrogenase-like protein; E=1e-18 COG: TM0436; COG1063 Threonine dehydrogenase and related Zn-dependent; E=7e-24 NMB0546; COG1064 Zn-dependent alcohol dehydrogenases; E=3e-15 PA2188; COG1063 Threonine dehydrogenase and related Zn-dependent; E=3e-15 PFAM: PF00899; ThiF family; E=0.34 PF02032; Phytoene dehydrogenase related; E=0.1 PF01494; FAD binding domain; E=0.0065. (386 aa)
adh-3Probable alcohol dehydrogenase (Zn-dependent); PMID: 3622514 best DB hits: BLAST: prf:2104227E; 2,3-butanediol dehydrogenase [Pseudomonas putida]; E=3e-40 pir:C83128; 2,3-butanediol dehydrogenase PA4153 [imported] -; E=4e-40 ddbj:BAB03906.1; (AP001507) sorbitol dehydrogenase [Bacillus; E=1e-38 COG: PA4153; COG1063 Threonine dehydrogenase and related Zn-dependent; E=4e-41 Rv3086; COG1062 Zn-dependent alcohol dehydrogenases, class III; E=7e-26 PFAM: PF00107; Zinc-binding dehydrogenases; E=4.4e-92. (346 aa)
RB6500Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...] (3665 aa)
RB9584Ripening-induced protein-putative Zn-containing oxidoreductase; Best DB hits: BLAST: embl:CAA04767.1; (AJ001445) ripening-induced protein [Fragaria; E=6e-31 pir:T10824; auxin-induced protein (clone MII-3) - mung bean -----; E=3e-29 swissprot:Q9ZUC1; QORL_ARATH QUINONE OXIDOREDUCTASE-LIKE PROTEIN; E=9e-27 COG: PA1137; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-24 PA5427; COG1064 Zn-dependent alcohol dehydrogenases; E=4e-10 VNG1821G; COG0604 NADPH:quinone reductase and related Zn-dependent; E=5e-10 PFAM: PF00107; Zinc-binding dehydrogenases; E=2.8e-68. (328 aa)
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.