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RB6403 RB6403 RB641 RB641 RB7410 RB7410 RB7461 RB7461 rpfC rpfC RB9879 RB9879 RB13181 RB13181 RB13175 RB13175 RB12326 RB12326 RB11986 RB11986 RB11091 RB11091 RB10924 RB10924 RB10488 RB10488 RB10322 RB10322 RB1656 RB1656 araC-2 araC-2 RB2872 RB2872 RB5275 RB5275 RB5964 RB5964
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RB6403Probable response regulator; PMID: 10910347 best DB hits: BLAST: pir:T34675; probable response regulator - Streptomyces coelicolor; E=1e-05 pir:A82535; transcription regulator LuxRUhpA family XF2608; E=4e-05 pir:T35105; probable two-component regulator - Streptomyces; E=7e-05 COG: XF2608; COG2197 Response regulators consisting of a CheY-like; E=4e-06 PA3420; COG2909 ATP-dependent transcriptional regulator; E=4e-04 PA3714; COG2197 Response regulators consisting of a CheY-like; E=4e-04 PFAM: PF00989; PAS domain; E=4.2e-06 PF00196; Bacterial regulatory proteins, luxR; E=3.1e-14. (304 aa)
RB641Sensory histidine protein kinase; Best DB hits: BLAST: pir:G82753; two-component system, sensor protein XF0853 [imported] -; E=2e-41 gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=8e-39 pir:A82300; sensory box sensor histidine kinaseresponse regulator; E=4e-34 COG: XF0853; COG0642 Sensory transduction histidine kinases; E=2e-42 sll0779_1; COG2202 PAS/PAC domain; E=1e-23 VCA0736_1; COG0642 Sensory transduction histidine kinases; E=1e-23 PFAM: PF00785; PAC motif; E=8.5e-08 PF00989; PAS domain; E=0.013 PF00785; PAC motif; E=0.1. (1170 aa)
RB7410Putative histidine kinase (PhoR1); Best DB hits: BLAST: embl:CAB37946.1; (AJ133131) putative histidine kinase (PhoR1); E=2e-43 swissprot:P35164; RESE_BACSU SENSOR PROTEIN RESE -----pir:; E=7e-40 embl:CAB64973.1; (AJ012050) VicK protein [Enterococcus faecalis]; E=1e-38 COG: BH4026; COG0642 Sensory transduction histidine kinases; E=2e-39 PFAM: PF00989; PAS domain; E=0.0015 PF00512; His Kinase A (phosphoacceptor) doma; E=9.2e-20 PF02518; Histidine kinase-, DNA gyrase B-, p; E=7.3e-38. (445 aa)
RB7461Probable sensor kinase; Best DB hits: BLAST: gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=2e-07 pir:S42745; nitrogen assimilation regulatory protein ntrC -; E=8e-07 swissprot:P45671; NTRC_AZOBR NITROGEN ASSIMILATION REGULATORY; E=4e-06 COG: VCA0142; COG2204 AAA superfamily ATPases with N-terminal receiver; E=7e-07 BB0570; COG0784 CheY-like receiver domains; E=6e-06 Rv0981; COG0745 Response regulators consisting of a CheY-like; E=9e-06 PFAM: PF01590; GAF domain; E=6.1e-16 PF00072; Response regulator receiver doma; E=7.9e-12. (614 aa)
rpfCBest DB hits: BLAST: pir:S75525; sensory transduction histidine kinase sll1228 -; E=3e-62 pir:S75136; sensory transduction histidine kinase slr2104 -; E=5e-60 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=1e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=9e-60 PFAM: PF00989; PAS domain; E=0.025 PF00785; PAC motif; E=0.012 PF00989; PAS domain; E=7.5e-05. (865 aa)
RB9879Best DB hits: BLAST: pir:C83489; probable transcription regulator PA1261 [imported] -; E=6e-26 pir:H83309; probable transcriptional regulator PA2696 [imported] -; E=8e-14 ddbj:BAB04708.1; (AP001510) transcriptional regulator (AraCXylS; E=1e-11 COG: PA1261; COG2207 AraC-type DNA-binding domain-containing proteins; E=5e-27 PFAM: PF00989; PAS domain; E=0.18 PF00165; Bacterial regulatory helix-turn-heli; E=7.6e-24. (245 aa)
RB13181PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=8e-57 pir:E82198; sensor histidine kinaseresponse regulator VC1445; E=4e-49 embl:CAA37397.1; (X53315) arcB [Escherichia coli]; E=3e-48 COG: sll1353_2; COG0642 Sensory transduction histidine kinases; E=7e-43 PFAM: PF00785; PAC motif; E=0.1 PF00989; PAS domain; E=8.8e-05 PF00785; PAC motif; E=9.8e-08. (953 aa)
RB13175PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-67 pir:S75142; sensory transduction histidine kinase slr1759 -; E=2e-55 embl:CAA65047.1; (X95731) putative sensor kinase [Synechocystis; E=3e-55 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-50 PFAM: PF00989; PAS domain; E=0.011 PF00785; PAC motif; E=0.075 PF00989; PAS domain; E=0.46. (1122 aa)
RB12326Sensory histidine protein kinase; PMID: 11406410 best DB hits: BLAST: gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=2e-45 pir:F83153; probable two-component sensor PA3946 [imported] -; E=3e-36 pir:E83265; probable two-component sensor PA3044 [imported] -; E=2e-35 COG: PA3044; COG0642 Sensory transduction histidine kinases; E=2e-36 PFAM: PF01590; GAF domain; E=3.2e-20 PF00989; PAS domain; E=1.2e-07 PF00512; His Kinase A (phosphoacceptor) d; E=4.8e-16. (718 aa)
RB11986Histidine protein kinase homolog GacS; PMID: 10762268 best DB hits: BLAST: gb:AAF04854.1; AF197912_1 (AF197912) histidine protein kinase; E=3e-57 pir:E83212; probable sensorresponse regulator hybrid PA3462; E=4e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=8e-51 COG: PA3462; COG0642 Sensory transduction histidine kinases; E=3e-57 PFAM: PF00989; PAS domain; E=3.5e-07 PF00512; His Kinase A (phosphoacceptor; E=2.5e-21 PF02518; Histidine kinase-, DNA gyrase; E=6.8e-39. (1182 aa)
RB11091Probable two-component sensor; PMID: 9045826 PMID: 10564511 best DB hits: BLAST: pir:F83324; probable two-component sensor PA2571 [imported] -; E=5e-36 pir:D82244; sensory box sensor histidine kinase VC1084 [imported] -; E=1e-35 pir:C82425; sensor histide kinase VCA0719 [imported] - Vibrio; E=2e-34 COG: PA2571; COG0642 Sensory transduction histidine kinases; E=5e-37 PFAM: PF00989; PAS domain; E=1.1e-06 PF00512; His Kinase A (phosphoacceptor) doma; E=0.001 PF02518; Histidine kinase-, DNA gyrase B-, p; E=2.9e-30. (769 aa)
RB10924Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (1739 aa)
RB10488PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42. (871 aa)
RB10322Two-component sensor histidine kinase; PMID: 10086841 PMID: 10086842 PMID: 10192928 best DB hits: BLAST: ddbj:BAB05639.1; (AP001513) two-component sensor histidine kinase; E=5e-22 swissprot:Q06067; ATOS_ECOLI SENSOR PROTEIN ATOS ----- pir:; E=1e-21 pir:S70528; sensor protein pilS - Myxococcus xanthus -----gb:; E=2e-21 COG: BH1920; COG0642 Sensory transduction histidine kinases; E=5e-23 PFAM: PF00785; PAC motif; E=0.099 PF00512; His Kinase A (phosphoacceptor) doma; E=7.9e-10 PF02518; Histidine kinase-, DNA gyrase B-, p; E=1.1e-33. (459 aa)
RB1656Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:C83287; hypothetical protein PA2870 [imported] - Pseudomonas; E=4e-29 pir:H70302; conserved hypothetical protein aq_035 - Aquifex aeolicus; E=1e-26 pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=9e-24 COG: PA2870; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=4e-30 TM1594; COG2199 Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); E=1e-22 PA0290_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=1e-22 PFAM: PF00989; PAS domain; E=2.5e-05 PF00990; GGDEF domain; E=5. [...] (875 aa)
araC-2Probable transcription regulator; PMID: 3902795 best DB hits: BLAST: pir:C83489; probable transcription regulator PA1261 [imported] -; E=2e-26 pir:D69749; transcription regulator AraCXylS family homolog ybfI -; E=2e-11 pir:F82380; transcription regulator AraCXylS family VCA1074; E=4e-11 COG: PA1261; COG2207 AraC-type DNA-binding domain-containing proteins; E=2e-27 BS_adaA; COG2169 Adenosine deaminase; E=3e-10 BH3842_2; COG2207 AraC-type DNA-binding domain-containing proteins; E=6e-10 PFAM: PF00165; Bacterial regulatory helix-turn-heli; E=5.4e-23. (254 aa)
RB2872Signal-transducing histidine kinase; PMID: 9278513 best DB hits: BLAST: gb:AAB89763.1; (AE001000) signal-transducing histidine kinase; E=3e-31 swissprot:Q9LCC2; PHYA_ANASP CYANOBACTERIAL PHYTOCHROME A -----; E=3e-28 swissprot:Q55168; PHY1_SYNY3 PHYTOCHROME-LIKE PROTEIN CPH1; E=1e-26 COG: slr0473_3; COG0642 Sensory transduction histidine kinases; E=1e-27 PFAM: PF00785; PAC motif; E=9.9e-06 PF00989; PAS domain; E=1.1e-07 PF00785; PAC motif; E=0.058. (659 aa)
RB5275Probable transcription regulator; PMID: 8451183 best DB hits: BLAST: pir:C83489; probable transcription regulator PA1261 [imported] -; E=1e-39 gb:AAF43900.1; (U20115) adpA-like protein [Mycobacterium; E=2e-10 pir:T43707; hypothetical protein [imported] - Streptomyces; E=2e-09 COG: PA1261; COG2207 AraC-type DNA-binding domain-containing proteins; E=1e-40 PFAM: PF00165; Bacterial regulatory helix-turn-heli; E=2.7e-22. (273 aa)
RB5964Probable response regulatory protein; Best DB hits: BLAST: pir:H70302; conserved hypothetical protein aq_035 - Aquifex aeolicus; E=1e-28 pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=3e-26 pir:E72220; conserved hypothetical protein - Thermotoga maritima; E=1e-24 COG: aq_035_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=1e-29 TM1699_2; COG2206 HD-GYP domain; E=1e-24 aq_563_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=2e-24 PFAM: PF01966; HD domain; E=6.6e-08 PF00989; PAS domain; E=0.032 PF00990; GGDEF domain; E=3.6e-53. (824 aa)
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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