STRINGSTRING
hyfR hyfR RB12326 RB12326 RB13175 RB13175 RB3373 RB3373 RB8274 RB8274 RB8745 RB8745 RB5734 RB5734 RB7190 RB7190 RB7461 RB7461 RB10473 RB10473 RB10793 RB10793
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hyfRHydrogenase-4 transcriptional activator; Best DB hits: BLAST: swissprot:P71229; HYFR_ECOLI HYDROGENASE-4 TRANSCRIPTIONAL; E=1e-83 pir:B65025; hypothetical protein b2491 - Escherichia coli (strain; E=1e-83 ddbj:BAA16380.1; (D90878) FORMATE HYDROGENLYASE TRANSCRIPTIONAL; E=1e-83 COG: hyfR_2; COG1221 NtrC family transcriptional regulators, ATPase; E=2e-77 hydG; COG2204 AAA superfamily ATPases with N-terminal receiver; E=4e-66 aq_1792_2; COG1221 NtrC family transcriptional regulators, ATPase; E=8e-66 PFAM: PF01590; GAF domain; E=9.9e-11 PF00158; Sigma-54 interaction domain; E=2.1e-138. (547 aa)
RB12326Sensory histidine protein kinase; PMID: 11406410 best DB hits: BLAST: gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=2e-45 pir:F83153; probable two-component sensor PA3946 [imported] -; E=3e-36 pir:E83265; probable two-component sensor PA3044 [imported] -; E=2e-35 COG: PA3044; COG0642 Sensory transduction histidine kinases; E=2e-36 PFAM: PF01590; GAF domain; E=3.2e-20 PF00989; PAS domain; E=1.2e-07 PF00512; His Kinase A (phosphoacceptor) d; E=4.8e-16. (718 aa)
RB13175PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-67 pir:S75142; sensory transduction histidine kinase slr1759 -; E=2e-55 embl:CAA65047.1; (X95731) putative sensor kinase [Synechocystis; E=3e-55 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-50 PFAM: PF00989; PAS domain; E=0.011 PF00785; PAC motif; E=0.075 PF00989; PAS domain; E=0.46. (1122 aa)
RB3373PMID: 9098081 best DB hits: BLAST: pir:T28655; receptor-like histidine kinase BpdS - Rhodococcus sp; E=1e-60 pir:T30898; receptor-like histidine kinase - Rhodococcus erythropolis; E=1e-60 pir:S75136; sensory transduction histidine kinase slr2104 -; E=9e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-41 PFAM: PF00069; Protein kinase domain; E=8.1e-08 PF00515; TPR Domain; E=0.026 PF00512; His Kinase A (phosphoacceptor); E=1.4e-21. (1998 aa)
RB8274Sensor protein atoS; PMID: 8346225 PMID: 9097040 best DB hits: BLAST: swissprot:Q06067; ATOS_ECOLI SENSOR PROTEIN ATOS -----pir:; E=2e-17 gb:AAD47419.1; AF100457_2 (AF100457) histidine kinase [Myxococcus; E=2e-16 ddbj:BAB04255.1; (AP001508) two-component sensor histidine kinase; E=3e-14 COG: atoS_3; COG0642 Sensory transduction histidine kinases; E=2e-18 Rv1827; COG1716 FHA-domain-containing proteins; E=1e-08 PA2882; COG0642 Sensory transduction histidine kinases; E=2e-08 PFAM: PF00498; FHA domain; E=3.2e-19 PF01590; GAF domain; E=4.8e-18 PF00512; His Kinase A (phosphoacceptor) doma; E [...] (623 aa)
RB8745PMID: 2722750 best DB hits: BLAST: swissprot:P12626; ANFA_AZOVI NITROGEN FIXATION PROTEIN ANFA; E=1e-64 pir:A48291; ornithine decarboxylase inhibitor - Escherichia coli; E=7e-61 swissprot:Q06065; ATOC_ECOLI ACETOACETATE METABOLISM REGULATORY; E=7e-61 COG: atoC; COG2204 AAA superfamily ATPases with N-terminal receiver; E=7e-62 ygeV_3; COG1221 NtrC family transcriptional regulators, ATPase; E=3e-61 TP0519; COG2204 AAA superfamily ATPases with N-terminal receiver; E=8e-60 PFAM: PF00498; FHA domain; E=1.4e-16 PF00158; Sigma-54 interaction domain; E=1.6e-129 PF02001; Protein of unknown func [...] (623 aa)
RB5734Conserved hypothetical protein; PMID: 8905231 best DB hits: BLAST: pir:S75932; hypothetical protein - Synechocystis sp. (strain PCC; E=1e-35 pir:B83298; conserved hypothetical protein PA2771 [imported] -; E=7e-07 pir:S76731; hypothetical protein - Synechocystis sp. (strain PCC; E=9e-06 COG: sll0048_1; COG2203 GAF domain; E=2e-27 PFAM: PF01590; GAF domain; E=2.5e-09. (287 aa)
RB7190Conserved hypothetical protein-putative regulatory protein; PMID: 10360571 best DB hits: BLAST: pir:C72374; hypothetical protein TM0467 - Thermotoga maritima; E=3e-16 embl:CAB56681.1; (AL121596) hypothetical protein SCF51A.29c; E=2e-14 embl:CAC01561.1; (AL391039) conserved hypothetical protein; E=4e-14 COG: TM0467; COG2208 Serine phosphatase RsbU, regulator of sigma subunit; E=3e-17 Rv1827; COG1716 FHA-domain-containing proteins; E=1e-09 slr1860_2; COG2208 Serine phosphatase RsbU, regulator of sigma; E=4e-09 PFAM: PF00498; FHA domain; E=1.4e-20 PF01590; GAF domain; E=3.5e-17. (634 aa)
RB7461Probable sensor kinase; Best DB hits: BLAST: gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=2e-07 pir:S42745; nitrogen assimilation regulatory protein ntrC -; E=8e-07 swissprot:P45671; NTRC_AZOBR NITROGEN ASSIMILATION REGULATORY; E=4e-06 COG: VCA0142; COG2204 AAA superfamily ATPases with N-terminal receiver; E=7e-07 BB0570; COG0784 CheY-like receiver domains; E=6e-06 Rv0981; COG0745 Response regulators consisting of a CheY-like; E=9e-06 PFAM: PF01590; GAF domain; E=6.1e-16 PF00072; Response regulator receiver doma; E=7.9e-12. (614 aa)
RB10473Best DB hits: BLAST: pir:D71687; alkaline proteinase secretion protein apre (aprE) RP314; E=0.032 pir:E82263; conserved hypothetical protein VC0913 [imported] -; E=0.053 gb:AAK03081.1; (AE006139) unknown [Pasteurella multocida]; E=0.13 COG: RP314; COG0845 Membrane-fusion protein; E=0.003 PFAM: PF01590; GAF domain; E=0.00029 PF00364; Biotin-requiring enzyme; E=0.0022. (811 aa)
RB10793Best DB hits: BLAST: pir:C83055; probable two-component response regulator PA4726; E=2e-58 gb:AAG59807.1; AF305914_2 (AF305914) HydG [Klebsiella oxytoca]; E=2e-58 pir:T08624; probable NtrC-type response regulator - Eubacterium; E=3e-58 COG: PA4726; COG2204 AAA superfamily ATPases with N-terminal receiver; E=2e-59 PA2359; COG1221 NtrC family transcriptional regulators, ATPase; E=2e-58 VC1926; COG2204 AAA superfamily ATPases with N-terminal receiver; E=2e-57 PFAM: PF01590; GAF domain; E=1.1e-13 PF00158; Sigma-54 interaction domain; E=1e-128. (654 aa)
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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