STRINGSTRING
RB6755 RB6755 RB7276 RB7276 lcfA lcfA RB9261 RB9261 ftsA ftsA RB12640 RB12640 RB2103 RB2103 RB386 RB386 RB6500 RB6500 aas aas acs acs
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
RB6755Peptide synthase-putative antibiotic synthesis; PMID: 10910347 best DB hits: BLAST: pir:B82579; peptide synthase XF2276 [imported] - Xylella fastidiosa; E=2e-93 embl:CAC18323.1; (AJ290449) feruloyl-CoA synthetase; E=1e-17 pir:C75364; probable long-chain-fatty-acid--CoA ligase (EC 6.2.1.3); E=3e-15 COG: XF2276; COG1020 Non-ribosomal peptide synthetase modules and related; E=2e-94 DR1692; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=3e-16 VNG1339C; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-15 PFAM: PF00501; AMP-binding enzyme; E=7.3e-05. (583 aa)
RB7276Peptide synthetase; PMID: 20392447 best DB hits: BLAST: embl:CAC01604.1; (AJ269505) peptide synthetase [Anabaena sp. 90]; E=4e-91 embl:CAC11137.1; (AJ250581) NikP1 protein [Streptomyces tendae]; E=9e-91 gb:AAF17281.1; (AF204805) NosD [Nostoc sp. GSV224]; E=4e-89 COG: PA2424_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=9e-85 BS_ppsC_1; COG1020 Non-ribosomal peptide synthetase modules and; E=5e-83 BS_dhbF; COG1020 Non-ribosomal peptide synthetase modules and related; E=2e-81 PFAM: PF00501; AMP-binding enzyme; E=2.2e-131 PF00550; Phosphopantetheine attachment; E=3.1e [...] (916 aa)
lcfAPMID: 8969504 best DB hits: BLAST: pir:E71667; 2-acylglycerophosphoethanolamine acyltransferase (aas); E=6e-18 gb:AAG19674.1; (AE005055) Vng1339c [Halobacterium sp. NRC-1]; E=5e-17 pir:A69831; probable acid--CoA ligase (EC 6.2.1.-) yhfL [similarity]; E=8e-17 COG: RP620_3; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=5e-19 VNG1339C; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=5e-18 BS_yhfL; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-18 PFAM: PF00501; AMP-binding enzyme; E=1.3e-08 PF01781; Ribosomal L38e protein family; E=0.56. (495 aa)
RB9261Conserved hypothetical protein; Best DB hits: BLAST: ddbj:BAA37082.1; (AB022095) ORF2 [Streptomyces griseus]; E=5e-45 embl:CAC04221.1; (AL391515) conserved hypothetical protein; E=9e-35 pir:G69070; coenzyme F390 synthetase I - Methanobacterium; E=0.004 COG: MTH1528; COG1541 Coenzyme F390 synthetase; E=4e-04 PFAM: PF00031; Cystatin domain; E=0.0015. (412 aa)
ftsABest DB hits: BLAST: gb:AAB89578.1; (AE000988) coenzyme F390 synthetase (ftsA-2); E=6e-37 pir:A69082; coenzyme F390 synthetase III - Methanobacterium; E=2e-36 pir:B69115; coenzyme F390 synthetase II - Methanobacterium; E=7e-36 COG: AF1671; COG1541 Coenzyme F390 synthetase; E=6e-38. (483 aa)
RB12640Probable auxin-responsive-like protein; PMID: 11538549 best DB hits: BLAST: gb:AAD32141.1; AF123503_1 (AF123503) Nt-gh3 deduced protein; E=6e-16 pir:T00515; hypothetical protein T20D16.20 - Arabidopsis thaliana; E=1e-15 ddbj:BAA97524.1; (AB026634) auxin-responsive-like protein; E=1e-14. (559 aa)
RB2103Acyl-CoA synthetase; PMID: 9634230 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-101 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=4e-96 gb:AAG02359.1; AF210249_18 (AF210249) peptide synthetase NRPS5-4-3; E=7e-93 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=4e-97 Rv3826; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-82 VNG1339C; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=9e-19 PFAM: PF00501; AMP-binding enzyme; E=1.7e-07 PF00550; Phosphopantetheine attachment sit; [...] (781 aa)
RB386Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...] (1204 aa)
RB6500Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...] (3665 aa)
aasAcyl-[ACP]--phospholipid O-acyltransferase; PMID: 8300626 best DB hits: BLAST: pir:A81368; probable 2-acylglycerophosphoethanolamine acyltransferase; E=2e-89 swissprot:P31119; AAS_ECOLI AAS BIFUNCTIONAL PROTEIN [INCLUDES:; E=5e-59 gb:AAG57948.1; AE005512_7 (AE005512); E=6e-59 COG: Cj0938c_3; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=6e-66 aas_2; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=6e-50 VNG1339C; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=2e-28 PFAM: PF01553; Acyltransferase; E=7.6e-22 PF00501; AMP-binding enzyme; E=2.4e-07. (766 aa)
acsAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (671 aa)
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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