node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DET0037 | carA | DET0037 | DET1201 | PyrK family protein. | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | 0.789 |
DET0037 | carB | DET0037 | DET1202 | PyrK family protein. | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to SP:P25994; match to protein family HMM TIGR01369; Belongs to the CarB family. | 0.797 |
DET0037 | pyrB | DET0037 | DET1199 | PyrK family protein. | Aspartate carbamoyltransferase; Identified by similarity to SP:P74163; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.790 |
DET0037 | pyrC | DET0037 | DET1200 | PyrK family protein. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.764 |
DET0037 | pyrD | DET0037 | DET1372 | PyrK family protein. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.979 |
DET0037 | pyrE | DET0037 | DET1193 | PyrK family protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.795 |
DET0037 | pyrF | DET0037 | DET0013 | PyrK family protein. | Orotidine 5'-phosphate decarboxylase; Identified by similarity to SP:Q9P9M3; match to protein family HMM TIGR02127; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.782 |
DET0819 | pyrE | DET0819 | DET1193 | Thymidylate synthase, putative; Identified by similarity to SP:P80305. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.403 |
DET0819 | thyX | DET0819 | DET1489 | Thymidylate synthase, putative; Identified by similarity to SP:P80305. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.922 |
DET0819 | tmk | DET0819 | DET0778 | Thymidylate synthase, putative; Identified by similarity to SP:P80305. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.941 |
carA | DET0037 | DET1201 | DET0037 | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | PyrK family protein. | 0.789 |
carA | carB | DET1201 | DET1202 | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to SP:P25994; match to protein family HMM TIGR01369; Belongs to the CarB family. | 0.999 |
carA | pyrB | DET1201 | DET1199 | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | Aspartate carbamoyltransferase; Identified by similarity to SP:P74163; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | DET1201 | DET1200 | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
carA | pyrD | DET1201 | DET1372 | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.965 |
carA | pyrE | DET1201 | DET1193 | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.962 |
carA | pyrF | DET1201 | DET0013 | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Identified by similarity to SP:Q9P9M3; match to protein family HMM TIGR02127; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.962 |
carA | pyrK | DET1201 | DET1203 | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | Dihydroorotate dehydrogenase, electron transfer subunit; Identified by similarity to SP:P25983. | 0.929 |
carB | DET0037 | DET1202 | DET0037 | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to SP:P25994; match to protein family HMM TIGR01369; Belongs to the CarB family. | PyrK family protein. | 0.797 |
carB | carA | DET1202 | DET1201 | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to SP:P25994; match to protein family HMM TIGR01369; Belongs to the CarB family. | Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P00907; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | 0.999 |