STRINGSTRING
gidB gidB fmt fmt argF argF GSU0227 GSU0227 GSU0291 GSU0291 cheR64H cheR64H hypF hypF gcvT gcvT GSU0434 GSU0434 rsmE rsmE prmA prmA GSU0476 GSU0476 trmB trmB GSU0544 GSU0544 GSU0549 GSU0549 purH purH GSU0628 GSU0628 GSU0630 GSU0630 GSU0632 GSU0632 GSU0637 GSU0637 trmD trmD GSU0647 GSU0647 rsmI rsmI GSU0679 GSU0679 GSU0690 GSU0690 ubiE ubiE GSU0900 GSU0900 GSU1047 GSU1047 rlmN rlmN cheR34H cheR34H ogt ogt trmL trmL GSU1214 GSU1214 GSU1244 GSU1244 pyrB pyrB GSU1327 GSU1327 GSU1369 GSU1369 GSU1375 GSU1375 accA accA GSU1420 GSU1420 GSU1440 GSU1440 GSU1452 GSU1452 rlmB rlmB trmJ trmJ GSU1513 GSU1513 pcm pcm glyA glyA panB panB GSU1748 GSU1748 purN purN rsmA rsmA GSU1926 GSU1926 pilD pilD GSU2107 GSU2107 cheR40H cheR40H GSU2318 GSU2318 GSU2329 GSU2329 accD accD GSU2387 GSU2387 GSU2411 GSU2411 GSU2441 GSU2441 GSU2476 GSU2476 GSU2510 GSU2510 trmFO trmFO GSU2626 GSU2626 bioC bioC GSU2749 GSU2749 GSU2792 GSU2792 metH metH metF-2 metF-2 cbiF cbiF cbiL cbiL cbiET cbiET cbiD cbiD GSU3018 GSU3018 rsmH rsmH rlmL rlmL hemK hemK GSU3105 GSU3105 thyX thyX GSU3545 GSU3545 GSU3144 GSU3144 cheR44H cheR44H rlmH rlmH cysG cysG hemD hemD GSU3320 GSU3320 rsmB rsmB GSU3442 GSU3442
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gidB16S rRNA (7-methyl-G527)-methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (217 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (317 aa)
argFOrnithine carbamyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (303 aa)
GSU0227DNA methyltransferase, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (305 aa)
GSU0291CheR-related putative SAM-binding domain protein. (352 aa)
cheR64HProtein glutamate methyltransferase CheR associated with MCPs of classes 40H and 40+24H; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (277 aa)
hypFHydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (763 aa)
gcvTGlycine cleavage system T protein. (362 aa)
GSU0434Thiamin biosynthesis protein ThiI-related adenine nucleotide alpha hydrolase superfamily protein. (334 aa)
rsmE16S rRNA (3-methyl-U1498)-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (260 aa)
prmARibosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (299 aa)
GSU0476Protein of unknown function DUF185. (386 aa)
trmBtRNA (N7-methyl-G46)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (209 aa)
GSU0544SAM-dependent methyltransferase, putative. (209 aa)
GSU0549SAM-dependent methyltransferase, putative. (226 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase. (521 aa)
GSU0628SAM-dependent methyltransferase, putative. (281 aa)
GSU0630SAM-dependent methyltransferase, type 11. (240 aa)
GSU0632SAM-dependent methyltransferase. (267 aa)
GSU0637SAM-dependent methyltransferase. (258 aa)
trmDtRNA (N1-methyl-G37)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (245 aa)
GSU0647Protein of unknown function DUF2168. (194 aa)
rsmI16S rRNA (2'-O-methyl-C1402)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (286 aa)
GSU0679SAM-dependent methyltransferase. (196 aa)
GSU0690rRNA methyltransferase, putative. (189 aa)
ubiEMenaquinone biosynthesis methyltransferase, putative; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (256 aa)
GSU0900SAM-dependent methyltransferase. (313 aa)
GSU1047SAM-dependent methyltransferase, putative. (360 aa)
rlmN23S rRNA (2-methyl-A2503)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (360 aa)
cheR34HProtein glutamate methyltransferase CheR associated with MCPs of class 34H; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (287 aa)
ogtMethylated DNA--protein cysteine S-methyltransferase. (182 aa)
trmLSpoU-class rRNA methyltransferase CspR; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (164 aa)
GSU1214Helix-turn-helix SAM-dependent methyltransferase. (333 aa)
GSU1244DNA methyltransferase, putative. (187 aa)
pyrBAspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (311 aa)
GSU1327Homocysteine S-methyltransferase domain protein. (318 aa)
GSU1369Endonuclease DUF559, putative. (122 aa)
GSU1375Hypothetical protein. (224 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
GSU1420rRNA methyltransferase, YqxC-related, putative. (263 aa)
GSU1440Hypothetical protein. (325 aa)
GSU1452RNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (495 aa)
rlmB23S rRNA (2'-O-methyl-G2251)-methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (245 aa)
trmJtRNA (2'O-methyl-C32/U32)-methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (255 aa)
GSU1513SAM-dependent methyltransferase, type 11. (308 aa)
pcmProtein L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (216 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (267 aa)
GSU1748RNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (438 aa)
purNPhosphoribosylglycinamide formyltransferase, folate-dependent; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (206 aa)
rsmA16S rRNA (6-N',N'-dimethyl-A1518,A1519)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (276 aa)
GSU1926Hypothetical protein. (197 aa)
pilDType IV prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (259 aa)
GSU2107Hypothetical protein. (1270 aa)
cheR40HProtein glutamate methyltransferase CheR associated with MCPs of class 40H; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (289 aa)
GSU2318Cyclopropane-fatty-acyl-phospholipid synthase, putative. (359 aa)
GSU2329Cyclopropane-fatty-acyl-phospholipid synthase. (421 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (280 aa)
GSU2387Corrinoid-binding domain protein. (226 aa)
GSU2411SAM-binding protein of unknown function UPF0066. (172 aa)
GSU2441SAM-dependent methyltransferase. (248 aa)
GSU2476TPR domain protein. (566 aa)
GSU2510SAM-dependent methyltransferase. (308 aa)
trmFOtRNA (5-methyl-U54)-methylenetransferase/reductase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (434 aa)
GSU2626SAM-dependent methyltransferase, PUA domain-containing. (396 aa)
bioCmalonyl-CoA O-methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (267 aa)
GSU2749NOL1/NOP2/Sun (tRNA and rRNA cytosine-C5-methyltransferase) family protein. (319 aa)
GSU2792SAM-dependent methyltransferase, putative. (250 aa)
metH5-methyltetrahydrofolate--homocysteine S-methyltransferase, cobalamin-dependent. (804 aa)
metF-25-methyltetrahydrofolate--homocysteine S-methyltransferase and 5,10-methylenetetrahydrofolate reductase. (605 aa)
cbiFCobalt-precorrin-4 C11-methyltransferase. (264 aa)
cbiLCobalt-sirohydrochlorin C20-methyltransferase; Belongs to the precorrin methyltransferase family. (236 aa)
cbiETcobalt-precorrin-6B C5,C15-methyltransferase and C12-decarboxylase. (405 aa)
cbiDcobalt-precorrin-5B C1-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (362 aa)
GSU3018SAM-dependent methyltransferase. (252 aa)
rsmH16S rRNA (N4-methyl-C1402)-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa)
rlmL23S rRNA (2-N-methyl-G2445)-methyltransferase, putative; Belongs to the methyltransferase superfamily. (391 aa)
hemKPeptide chain release factor methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (284 aa)
GSU3105Protein of unknown function DUF1385. (317 aa)
thyXThymidylate synthase, FAD-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (232 aa)
GSU3545Hypothetical protein. (234 aa)
GSU3144SAM-dependent methyltransferase, putative. (402 aa)
cheR44HProtein glutamate methyltransferase CheR associated with MCPs of class 44H. (307 aa)
rlmH23S rRNA (3-N-methyl-pseudoU1915)-methyltransferase, putative; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (153 aa)
cysGPrecorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative. (224 aa)
hemDUroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase. (515 aa)
GSU3320SAM-dependent methyltransferase, putative. (198 aa)
rsmB16S rRNA (5-methyl-C967)-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (448 aa)
GSU3442Protein of unknown function DUF488. (114 aa)
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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