STRINGSTRING
acnA acnA hemD hemD hisB hisB omcO omcO GSU2899 GSU2899 omcN omcN omcA omcA omcH omcH omcG omcG GSU2724 GSU2724 pheA pheA GSU2493 GSU2493 GSU2445 GSU2445 trpB2 trpB2 trpB1 trpB1 trpA trpA rmlB rmlB can-2 can-2 eno eno fabZ-2 fabZ-2 GSU2186 GSU2186 aroC aroC aroB aroB aroQ aroQ mqnA mqnA ilvD ilvD leuC leuC leuD leuD GSU1841 GSU1841 yjeF yjeF queD queD thrC thrC acnB acnB nth-2 nth-2 GSU1442 GSU1442 GSU1056 GSU1056 GSU1000 GSU1000 mutM mutM fumB fumB GSU0880 GSU0880 GSU0809 GSU0809 GSU0702 GSU0702 gmd gmd fabZ-1 fabZ-1 dapA dapA hemB hemB can-1 can-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acnAAconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (935 aa)
hemDUroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase. (515 aa)
hisBImidazoleglycerol-phosphate dehydratase. (195 aa)
omcOCytochrome c; 27 heme-binding sites. (1046 aa)
GSU2899Lipoprotein cytochrome c; 23 heme-binding sites. (979 aa)
omcNLipoprotein cytochrome c; 34 heme-binding sites. (2803 aa)
omcACytochrome c; 27 heme-binding sites. (1018 aa)
omcHCytochrome c; 24 heme-binding sites. (902 aa)
omcGCytochrome c; 18 heme-binding sites. (710 aa)
GSU2724Cytochrome c; 15 heme-binding sites. (691 aa)
pheAChorismate mutase and prephenate dehydratase. (358 aa)
GSU2493NHL repeat domain protein. (301 aa)
GSU2445Aconitate hydratase, putative. (645 aa)
trpB2Tryptophan synthase, homodimeric beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (451 aa)
trpB1Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (264 aa)
rmlBdTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (358 aa)
can-2Carbonic anhydrase, beta-family, clade B; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (211 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
fabZ-2(3R)-hydroxyacyl-(acyl carrier protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa)
GSU2186Hypothetical protein. (389 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (393 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (362 aa)
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (150 aa)
mqnAFutalosine synthase, putative; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (273 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (553 aa)
leuCIsopropylmalate/citramalate isomerase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (427 aa)
leuDIsopropylmalate/citramalate isomerase, small subunit; Belongs to the LeuD family. (175 aa)
GSU1841Membrane protein, putative. (129 aa)
yjeFATP-binding protein YjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both [...] (519 aa)
queD6-carboxy-5,6,7,8-tetrahydropterin synthase. (122 aa)
thrCThreonine synthase. (461 aa)
acnBAconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (847 aa)
nth-2Endonuclease III-related DNA glycosidase, HhH-GPD superfamily; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (218 aa)
GSU1442Carbonic anhydrase, beta-family, clade C. (233 aa)
GSU1056Protein of unknown function UPF0047. (133 aa)
GSU1000Hypothetical protein. (435 aa)
mutMformamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (271 aa)
fumBFumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (541 aa)
GSU0880Molybdopterin-binding iron-sulfur cluster-binding oxidoreductase MopB-3; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (671 aa)
GSU0809Carbonic anhydrase, beta-family, clade D. (181 aa)
GSU0702Lipoprotein cytochrome c; 35 heme-binding sites. (1916 aa)
gmdGDP-mannose 4,6-dehydratase and GDP-6-deoxy-D-lyxo-4-hexulose reductase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (349 aa)
fabZ-1(3R)-hydroxyacyl-(acyl carrier protein) dehydratase. (129 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa)
hemBPorphobilinogen synthase; Belongs to the ALAD family. (325 aa)
can-1Carbonic anhydrase, beta-family, clade B. (215 aa)
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.