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gcvT gcvT gcvH-1 gcvH-1 gcvP1 gcvP1 gcvP2 gcvP2 fdnG fdnG fdnH fdnH acnA acnA gltA gltA mdh mdh GSU1578 GSU1578 glyA glyA glcD-2 glcD-2 glcF-2 glcF-2 acnB acnB hprA hprA glnA glnA gcvH-2 gcvH-2 GSU2192 GSU2192 GSU2445 GSU2445 lpdA-1 lpdA-1 lpdA-2 lpdA-2 glcD-1 glcD-1 glcF-1 glcF-1 GSU3302 GSU3302 mceE mceE GSU3349 GSU3349
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcvTGlycine cleavage system T protein. (362 aa)
gcvH-1Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (124 aa)
gcvP1Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
gcvP2Glycine cleavage system P protein, subunit 2. (481 aa)
fdnGPeriplasmically oriented, membrane-bound formate dehydrogenase, major subunit, selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1010 aa)
fdnHPeriplasmically oriented, membrane-bound formate dehydrogenase, iron-sulfur cluster-binding subunit. (277 aa)
acnAAconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (935 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (441 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (317 aa)
GSU1578(R)-methylmalonyl-CoA mutase, adenosylcobamide-binding subunit. (134 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
glcD-2D-lactate/glycolate dehydrogenase, FAD-binding protein, putative. (457 aa)
glcF-2D-lactate/glycolate dehydrogenase, iron-sulfur cluster-binding protein, putative. (416 aa)
acnBAconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (847 aa)
hprAHydroxypyruvate reductase, putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
glnAGlutamine synthetase, type I. (470 aa)
gcvH-2Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (132 aa)
GSU2192HAD superfamily hydrolase. (217 aa)
GSU2445Aconitate hydratase, putative. (645 aa)
lpdA-1Dihydrolipoamide dehydrogenase. (472 aa)
lpdA-2Dihydrolipoamide dehydrogenase. (452 aa)
glcD-1D-lactate/glycolate dehydrogenase, FAD-binding protein, putative. (459 aa)
glcF-1D-lactate/glycolate dehydrogenase, iron-sulfur cluster-binding protein, putative. (421 aa)
GSU3302(R)-methylmalonyl-CoA mutase, isobutyryl-CoA mutase-like catalytic subunit. (552 aa)
mceEmethylmalonyl-CoA epimerase. (134 aa)
GSU3349Cyclase/hydrolase, putative. (227 aa)
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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