Conserved hypothetical protein; Similar to GB:L42023 SP:P45106 PID:1007078 PID:1221325 PID:1205444 percent identity: 24.82; identified by sequence similarity; putative; Belongs to the methyltransferase superfamily.

Protoporphyrinogen oxidase (hemK); Putative protein methyltransferase using S-adenosyl-L- methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity); Belongs to the eukaryotic/archaeal PrmC-related family.

Conserved hypothetical protein; Similar to GB:L42023 SP:P45106 PID:1007078 PID:1221325 PID:1205444 percent identity: 24.82; identified by sequence similarity; putative; Belongs to the methyltransferase superfamily.

Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

Conserved hypothetical protein; Similar to GB:L42023 SP:P45106 PID:1007078 PID:1221325 PID:1205444 percent identity: 24.82; identified by sequence similarity; putative; Belongs to the methyltransferase superfamily.

Dimethyladenosine transferase (ksgA); Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.

Unspecified methyltransferase; Similar to PIR:S21265 percent identity: 25.50; identified by sequence similarity; putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.

Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

Unspecified methyltransferase; Similar to PIR:S21265 percent identity: 25.50; identified by sequence similarity; putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.

Dimethyladenosine transferase (ksgA); Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.

Modification methylase, type II R/M system; Similar to SP:P50192 percent identity: 35.29; identified by sequence similarity; putative.

Modification methylase, type II R/M system; Similar to SP:P05302 percent identity: 40.20; identified by sequence similarity; putative.

Conserved hypothetical protein; Radical SAM methyltransferase that is responsible for the C(5)-methylation of 'Arg-274' of the methyl-coenzyme M reductase (MCR) subunit alpha McrA. This post-translational methylation, despite being not essential in vivo, plays a role for the stability and structural integrity of MCR.

N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit H (mtrH); Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.

Conserved hypothetical protein; Probable methyltransferase that uses S-adenosylmethionine as the methyl donor. Binds neither NAD nor NADP in vitro.

Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

Conserved hypothetical protein; Probable methyltransferase that uses S-adenosylmethionine as the methyl donor. Binds neither NAD nor NADP in vitro.

Cell division protein FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

Conserved hypothetical protein; Probable methyltransferase that uses S-adenosylmethionine as the methyl donor. Binds neither NAD nor NADP in vitro.

Proliferating-cell nucleolar antigen, FMU/NOL1/NOP2 family; Catalyzes AdoMet-dependent formation of m5C in tRNA. Cytidine residue at either position 40 or position 48 is likely to be methylated; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

Conserved hypothetical protein; Probable methyltransferase that uses S-adenosylmethionine as the methyl donor. Binds neither NAD nor NADP in vitro.

Conserved hypothetical protein; Specifically methylates the N1 position of guanosine-37 in various tRNAs.

Protoporphyrinogen oxidase (hemK); Putative protein methyltransferase using S-adenosyl-L- methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity); Belongs to the eukaryotic/archaeal PrmC-related family.

Conserved hypothetical protein; Similar to GB:L42023 SP:P45106 PID:1007078 PID:1221325 PID:1205444 percent identity: 24.82; identified by sequence similarity; putative; Belongs to the methyltransferase superfamily.

Protoporphyrinogen oxidase (hemK); Putative protein methyltransferase using S-adenosyl-L- methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity); Belongs to the eukaryotic/archaeal PrmC-related family.

5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity).

Protoporphyrinogen oxidase (hemK); Putative protein methyltransferase using S-adenosyl-L- methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity); Belongs to the eukaryotic/archaeal PrmC-related family.

Dimethyladenosine transferase (ksgA); Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.

Protoporphyrinogen oxidase (hemK); Putative protein methyltransferase using S-adenosyl-L- methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity); Belongs to the eukaryotic/archaeal PrmC-related family.

N2,N2-dimethylguanosine tRNA methyltransferase (trm1); Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

Protoporphyrinogen oxidase (hemK); Putative protein methyltransferase using S-adenosyl-L- methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity); Belongs to the eukaryotic/archaeal PrmC-related family.

Conserved hypothetical protein; Catalyzes the formation of 2'O-methylated cytidine (Cm32) at position 32 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

Modification methylase, type II R/M system; Similar to SP:P05302 percent identity: 40.20; identified by sequence similarity; putative.

Modification methylase, type II R/M system; Similar to SP:P50192 percent identity: 35.29; identified by sequence similarity; putative.

Modification methylase, type II R/M system; Similar to SP:P05302 percent identity: 40.20; identified by sequence similarity; putative.

Modification methylase, type II R/M system 2; This methylase recognizes the double-stranded sequence GATC, causes specific methylation on A-2 on both strands, and protects the DNA from cleavage by the MjaIII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family.

Modification methylase, type II R/M system; Similar to SP:P05302 percent identity: 40.20; identified by sequence similarity; putative.

Modification methylase, type II R/M system; This methylase recognizes the double-stranded sequence CCGG, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by the MjaVI endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

Type I restriction-modification enzyme 1, M subunit; Similar to GB:L25415 PID:496158 percent identity: 32.85; identified by sequence similarity; putative.

Modification methylase, type II R/M system; This methylase recognizes the double-stranded sequence GTNNAC, causes specific methylation on ? on both strands, and protects the DNA from cleavage by the MjaIV endonuclease.