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frdB frdB frdD frdD plu4258 plu4258 dusA dusA plu4387 plu4387 hemG hemG wecC wecC wblA wblA tyrA tyrA plu1192 plu1192 plu1176 plu1176 hpaB hpaB plu0762 plu0762 pyrD pyrD sdhA sdhA sdhD sdhD sdhC sdhC hemF hemF plu1321 plu1321 luxC luxC hcaB hcaB plu2336 plu2336 fabI fabI plu2965 plu2965 cbiJ cbiJ plu3562 plu3562 plu3917 plu3917 fadH fadH plu4027 plu4027 dusB dusB frdA frdA frdC frdC cysG cysG dapB dapB plu0246 plu0246 hemN hemN dusC dusC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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frdBFumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
frdDFumarate reductase 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (117 aa)
plu4258Unnamed protein product; Similar to 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component HpaB. (481 aa)
dusAtRNA-dihydrouridine(20/20a) synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (345 aa)
plu4387Unnamed protein product; Some similarities with isobutylamine N-hydroxylase and putative oxidoreductase. (348 aa)
hemGProtoporphyrinogen oxidase (PPO). (178 aa)
wecCUDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (UDP-ManNAca dehydrogenase); Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
wblAWblA protein; Similar to putative UDP-glucose/GDP-mannose dehydrogenase. (436 aa)
tyrAT-protein [includes: chorismate mutase (CM); prephenate dehydrogenase (PDH)]. (373 aa)
plu1192Unnamed protein product; Highly similar to putative acyl-CoA dehydrogenase YafH of Escherichia coli. (811 aa)
plu1176Heme chaperone HemW; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (376 aa)
hpaB4-hydroxyphenylacetate 3-monooxygenase, oxygenase component (4-HPA 3-monooxygenase large component) (4-HPA 3-hydroxylase). (520 aa)
plu0762Unnamed protein product; Some similarities with acyl-Coenzyme A dehydrogenase. (359 aa)
pyrDDihydroorotate dehydrogenase (dihydroorotate oxidase) (dhodehase) (dhodase) (dhod); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (336 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
sdhDSuccinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
sdhCSuccinate dehydrogenase cytochrome b-556 subunit. (83 aa)
hemFOxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (302 aa)
plu1321Unnamed protein product; Weakly similar to unknown protein. (254 aa)
luxCFatty acid reductase; LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase. (480 aa)
hcaB2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Converts 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol) into 3-(2,3- dihydroxylphenyl)propanoic acid (DHPP) and 2,3-dihydroxicinnamic acid (DHCI), respectively; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (280 aa)
plu2336Uncharacterized protein; Truncated gene. Similar to C-terminal region of insecticidal toxin complex protein TccB from Photorhabdus luminescens. (587 aa)
fabIEnoyl-[acyl-carrier-protein] reductase [NADH] (NADH-dependent enoyl-ACP reductase). (262 aa)
plu2965Unnamed protein product; Highly similar to the N-terminal region of siroheme synthase activity. (222 aa)
cbiJPrecorrin-6X reductase. (261 aa)
plu3562Unnamed protein product; Similar to dehydrogenase PapC of Streptomyces pristinaespiralis. (295 aa)
plu3917DHO_dh domain-containing protein; Catalyzes the conversion of dihydroorotate to orotate. (289 aa)
fadH2,4-dienoyl-CoA reductase [NADPH] (2,4-dienoyl coenzyme A reductase). (673 aa)
plu4027Unnamed protein product; Similar to 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component HpaB. (519 aa)
dusBtRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (321 aa)
frdAFumarate reductase flavoprotein subunit. (598 aa)
frdCFumarate reductase 15 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (130 aa)
cysGSirohaem synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (470 aa)
dapBDihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa)
plu0246Unnamed protein product; Similar to 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component HpaB. (517 aa)
hemNOxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. (457 aa)
dusCtRNA-dihydrouridine(16) synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. (310 aa)
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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