STRINGSTRING
phoQ phoQ rcsB rcsB rcsC rcsC lsrK lsrK lsrB lsrB tctE tctE tctD tctD plu3220 plu3220 plu3236 plu3236 plu3252 plu3252 plu3311 plu3311 plu3313 plu3313 prpR prpR plu3720 plu3720 plu3798 plu3798 phoR phoR phoB phoB arcB arcB plu4441 plu4441 fecR fecR cpxA cpxA cpxR cpxR plu4562 plu4562 plu4521 plu4521 plu0102 plu0102 plu0103 plu0103 ompR ompR envZ envZ glnG glnG glnL glnL plu0305 plu0305 arcA arcA rcsF rcsF plu0740 plu0740 uhpB uhpB uhpA uhpA barA barA plu1070 plu1070 luxS luxS plu1269 plu1269 kdpE kdpE kdpD kdpD cheA cheA cheW cheW cheD cheD plu1854 plu1854 cheB cheB cheY cheY plu2003 plu2003 plu2004 plu2004 plu2005 plu2005 plu2006 plu2006 plu2007 plu2007 plu2008 plu2008 plu2009 plu2009 plu2010 plu2010 plu2011 plu2011 plu2012 plu2012 plu2013 plu2013 plu2015 plu2015 uvrY uvrY plu2041 plu2041 bvgS bvgS bvgR bvgR plu2475 plu2475 hnr hnr plu2532 plu2532 plu2535 plu2535 pspF pspF narP narP baeS baeS baeR baeR phoP phoP rcsD rcsD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
phoQTwo-component sensor kinase PhoQ. (487 aa)
rcsBCapsular synthesis regulator component B; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. (217 aa)
rcsCSensor protein (capsular synthesis regulator component C); Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (938 aa)
lsrKAutoinducer-2 kinase; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. (530 aa)
lsrBABC transporter Binding Protein (BP) LsrB; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity). (339 aa)
tctETwo-component sensor kinase. (473 aa)
tctDTwo-component response regulator. (225 aa)
plu3220HTH luxR-type domain-containing protein; Unnamed protein product; Similar to probable transcription regulator, LuxR family. (228 aa)
plu3236Unnamed protein product; Similar to unknown protein. (538 aa)
plu3252Unnamed protein product; Similar to unknown protein. (536 aa)
plu3311Unnamed protein product; Highly similar to putative 2-component transcriptional regulator YfhA of Escherichia coli. (445 aa)
plu3313Unnamed protein product; Highly similar to putative sensor-like histidine kinase (two-component sensor protein kinase) YfhK of Escherichia coli. (498 aa)
prpRPropionate catabolism operon regulatory protein. (555 aa)
plu3720HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator LuxR family. (226 aa)
plu3798Sigma-54 factor interaction domain-containing protein; Unnamed protein product; Similar to the central region of response regulator of AtoC, ornithine/arginine decarboxylase inhibitor (ornithine decarboxylase antizyme). (134 aa)
phoRPhosphate regulon sensor protein. (446 aa)
phoBPhosphate regulon transcriptional regulatory protein. (229 aa)
arcBAerobic respiration control sensor protein. (781 aa)
plu4441OmpR/PhoB-type domain-containing protein; Unnamed protein product; Some similarities with putative transcription regulator and with unknown protein of Photorhabdus. (123 aa)
fecRProtein fecR. (321 aa)
cpxATwo-component sensor kinase. (456 aa)
cpxRTwo-component response regulator. (231 aa)
plu4562HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcription regulator. (238 aa)
plu4521Unnamed protein product; Highly similar to unknown protein YehT of Escherichia coli. (240 aa)
plu0102Unnamed protein product; Similar to two-component sensor kinase. (454 aa)
plu0103Unnamed protein product; Similar to two-component response regulator. (208 aa)
ompRTwo-component response regulator. (239 aa)
envZOsmolarity sensor protein. (443 aa)
glnGNitrogen regulation protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (490 aa)
glnLNitrogen regulation protein. (349 aa)
plu0305GAPES3 domain-containing protein; Unnamed protein product; Similar to putative membrane protein YhjK of Escherichia coli. (237 aa)
arcATwo-component system, OmpR family, aerobic respiration control protein ArcA; Negative response regulator of genes in aerobic pathways, (sensors, ArcB and CpxA) (dye resistance protein). (238 aa)
rcsFExopolysaccharide synthesis regulatory protein RcsF; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. (132 aa)
plu0740Unnamed protein product; Some similarities with probable transmembrane sensor. (337 aa)
uhpBTwo-component sensor histidine kinase UhpB, phosphorylates UhpA. (514 aa)
uhpATwo-component response regulator. Hexose phosphate transport system regulatory protein UhpA. (210 aa)
barASensor protein BarA. (775 aa)
plu1070Unnamed protein product; Similar to unknown protein. (178 aa)
luxSAutoinducer-2 (AI-2) production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa)
plu1269Polyphenol oxidase; Unnamed protein product; Highly similar to unknown protein YfiH of Escherichia coli; Belongs to the multicopper oxidase YfiH/RL5 family. (243 aa)
kdpETranscriptional regulatory protein of kdp operon. (230 aa)
kdpDSensor protein (histidine kinase). (897 aa)
cheAChemotaxis protein cheA. (683 aa)
cheWPurine binding chemotaxis protein. (165 aa)
cheDMethyl-accepting chemotaxis protein I (MCP-I) (Serine chemoreceptor protein). (564 aa)
plu1854Unnamed protein product; Similar to methyl-accepting chemotaxis protein I (MCP-I) (Serine chemoreceptor protein). (544 aa)
cheBProtein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (350 aa)
cheYChemotaxis protein CheY. (129 aa)
plu2003HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LuxR family. (226 aa)
plu2004HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LuxR family. (226 aa)
plu2005HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LuxR family. (226 aa)
plu2006HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LuxR family. (226 aa)
plu2007HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LuxR family. (226 aa)
plu2008HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LuxR family. (226 aa)
plu2009HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LuxR family. (227 aa)
plu2010HTH luxR-type domain-containing protein; Unnamed protein product; Similar to transcriptional regulator, LuxR family. (226 aa)
plu2011HTH luxR-type domain-containing protein; Unnamed protein product; Weakly similar to transcriptional regulator, LuxR family. (226 aa)
plu2012HTH luxR-type domain-containing protein; Unnamed protein product; Weakly similar to transcriptional regulator, LuxR family. (226 aa)
plu2013HTH luxR-type domain-containing protein; Truncated gene. Some similarities with probable transcriptional regulator, LuxR family protein of Photorhabdus. (226 aa)
plu2015HTH luxR-type domain-containing protein; Unnamed protein product; Weakly similar to transcriptional regulator, LuxR family. (225 aa)
uvrYTranscription regulator. (221 aa)
plu2041Histidine kinase domain-containing protein; Unnamed protein product; Similar to nitrate/nitrite sensor protein NarX. (410 aa)
bvgSVirulence sensor protein BvgS precursor. (1203 aa)
bvgRTwo-component response regulator BvgR protein. (208 aa)
plu2475Unnamed protein product; Similar to N-terminal region of WD-repeat protein, encoded by the toxC gene of Burkholderia glumae, involved in toxoflavin biosynthesis. (561 aa)
hnrHnr protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. (341 aa)
plu2532OmpR/PhoB-type domain-containing protein; Unnamed protein product; Similar to unknown protein of Photorhabdus and some similarities with unknown protein. (197 aa)
plu2535OmpR/PhoB-type domain-containing protein; Unnamed protein product; Highly similar to unknown protein of Photorhabdus and some similarities with unknown protein. (197 aa)
pspFPsp operon transcriptional activator PspF. (340 aa)
narPNitrate/nitrite response regulator protein NarP. (211 aa)
baeSTwo-component sensor kinase. (462 aa)
baeRTwo-component response regulator. (234 aa)
phoPTwo-component response regulator PhoP. (222 aa)
rcsDPhosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (896 aa)
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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