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| fba | Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (288 aa) | ||||
| upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (206 aa) | ||||
| tdk | Thymidine kinase; Identified by similarity to SP:Q03221; match to protein family HMM PF00265. (213 aa) | ||||
| ptsH | Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. (88 aa) | ||||
| deoD | Purine nucleoside phosphorylase; Identified by similarity to SP:P09743; match to protein family HMM PF01048; match to protein family HMM TIGR00107; Belongs to the PNP/UDP phosphorylase family. (238 aa) | ||||
| deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (223 aa) | ||||
| pdp | Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. (421 aa) | ||||
| cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (130 aa) | ||||
| manB | Phosphoglucomutase/phosphomannomutase, putative; Identified by similarity to EGAD:56902; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; Belongs to the phosphohexose mutase family. (550 aa) | ||||
| prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (332 aa) | ||||
| fruA | PTS system, fructose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. (680 aa) | ||||
| fruK | 1-phosphofructokinase, putative; Identified by similarity to GB:AAF08321.1; match to protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. (303 aa) | ||||
| tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (648 aa) | ||||
| ptsG | PTS system, glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. (908 aa) | ||||
| pgi | Glucose-6-phosphate isomerase; MG111 has 1 transmembrane region; identified by similarity to SP:P81181; match to protein family HMM PF00342. (433 aa) | ||||
| rpe | Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family. (209 aa) | ||||
| pfk | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (323 aa) | ||||
| lplA | Lipoyltransferase/lipoate-protein ligase, putative; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes; Belongs to the LplA family. (336 aa) | ||||
| lpdA | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (457 aa) | ||||
| pdhC | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (384 aa) | ||||
| pdhB | Pyruvate dehydrogenase component E1, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (326 aa) | ||||
| pdhA | Pyruvate dehydrogenase component E1, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (358 aa) | ||||
| nox | NADH oxidase; Catalyzes the four-electron reduction of molecular oxygen to water; Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family. (478 aa) | ||||
| pta | Phosphate acetyltransferase; Identified by similarity to SP:P39646; match to protein family HMM PF01515; match to protein family HMM TIGR00651. (320 aa) | ||||
| pgk | Phosphoglycerate kinase; Identified by similarity to SP:P36204; match to protein family HMM PF00162. (411 aa) | ||||
| gap | Glyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. (337 aa) | ||||
| ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (393 aa) | ||||
| udk | Uridine kinase; Identified by similarity to EGAD:57059; match to protein family HMM PF00485; match to protein family HMM TIGR00235. (213 aa) | ||||
| rpiB | Ribose 5-phosphate isomerase B; Catalyzes the interconversion of ribulose-5-P and ribose-5-P. Belongs to the LacAB/RpiB family. (152 aa) | ||||
| eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (458 aa) | ||||
| ptsI | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (572 aa) | ||||
| gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (507 aa) | ||||
| tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (244 aa) | ||||
| ldh | L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (312 aa) | ||||